Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Timothy McKinsey

Concepts (682)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Histone Deacetylases
74
2024
212
13.440
Why?
Histone Deacetylase Inhibitors
33
2023
209
6.890
Why?
Cardiomegaly
35
2025
172
6.210
Why?
Myocardium
38
2025
978
5.310
Why?
Myocytes, Cardiac
37
2025
499
5.160
Why?
Heart Failure
32
2025
2135
4.940
Why?
Fibroblasts
26
2024
948
3.240
Why?
Fibrosis
20
2024
520
3.070
Why?
Heart
18
2022
637
2.990
Why?
Ventricular Remodeling
14
2025
255
2.940
Why?
Transcription Factors
33
2024
1647
2.610
Why?
Protein Kinase C
18
2015
260
2.530
Why?
Nuclear Proteins
10
2024
659
2.100
Why?
Myofibrils
8
2023
49
2.020
Why?
Signal Transduction
54
2025
4926
2.000
Why?
Animals
142
2025
35309
1.950
Why?
Epigenesis, Genetic
12
2023
616
1.820
Why?
Adipocytes
5
2025
204
1.820
Why?
Myofibroblasts
5
2023
121
1.790
Why?
Thermogenesis
4
2025
44
1.740
Why?
Hypertrophy, Right Ventricular
4
2021
145
1.710
Why?
Rats
49
2022
5482
1.690
Why?
Chromatin
10
2024
478
1.510
Why?
Extracellular Matrix
6
2023
502
1.500
Why?
Gene Expression Regulation
32
2022
2537
1.450
Why?
Cells, Cultured
36
2024
4077
1.440
Why?
Mice
67
2025
16915
1.400
Why?
Rats, Sprague-Dawley
31
2021
2396
1.350
Why?
Dual-Specificity Phosphatases
3
2021
11
1.300
Why?
Protein Processing, Post-Translational
8
2023
454
1.250
Why?
Hypertension, Pulmonary
11
2021
1894
1.210
Why?
Histones
13
2020
588
1.200
Why?
Azepines
4
2024
88
1.190
Why?
Heart Ventricles
13
2022
781
1.160
Why?
Angiotensin II
5
2021
95
1.120
Why?
Triazoles
4
2024
151
1.110
Why?
Adipose Tissue
4
2025
590
1.100
Why?
Myocardial Reperfusion Injury
2
2024
129
1.050
Why?
Heart-Assist Devices
2
2022
539
0.990
Why?
Gene Expression Regulation, Enzymologic
7
2019
286
0.980
Why?
Cell Cycle Proteins
5
2024
584
0.970
Why?
Phosphorylation
27
2023
1710
0.970
Why?
DNA-Binding Proteins
32
2005
1446
0.950
Why?
Hydroxamic Acids
6
2018
88
0.940
Why?
Lysine
6
2022
286
0.930
Why?
Muscle, Skeletal
12
2023
1613
0.920
Why?
Vascular Remodeling
3
2021
192
0.910
Why?
Acetylation
15
2020
244
0.900
Why?
Humans
103
2025
129266
0.860
Why?
Myocytes, Smooth Muscle
5
2021
259
0.860
Why?
A Kinase Anchor Proteins
1
2024
71
0.840
Why?
Catecholamines
1
2023
96
0.840
Why?
Sarcomeres
3
2022
92
0.830
Why?
Disease Models, Animal
23
2025
4057
0.830
Why?
Histocompatibility Antigens Class II
1
2024
363
0.820
Why?
Heart Diseases
4
2021
350
0.810
Why?
Repressor Proteins
15
2019
406
0.800
Why?
Myocardial Infarction
4
2024
1021
0.800
Why?
Adipose Tissue, Brown
2
2023
51
0.790
Why?
Rejuvenation
1
2022
18
0.790
Why?
Aortic Valve Insufficiency
1
2022
46
0.760
Why?
Cell Proliferation
5
2021
2375
0.750
Why?
Assisted Circulation
1
2021
26
0.740
Why?
Mice, Inbred C57BL
22
2025
5439
0.740
Why?
Macrophages
5
2024
1484
0.730
Why?
Heart Murmurs
1
2021
12
0.720
Why?
MEF2 Transcription Factors
20
2020
60
0.720
Why?
Animals, Newborn
14
2017
834
0.720
Why?
Cell Nucleus
13
2015
586
0.720
Why?
Ventricular Dysfunction, Left
2
2022
385
0.720
Why?
Obesity
4
2025
2879
0.710
Why?
Epigenomics
3
2021
110
0.690
Why?
Arteries
1
2022
265
0.680
Why?
Phosphoric Monoester Hydrolases
1
2020
54
0.680
Why?
Aortic Diseases
1
2021
113
0.680
Why?
Muscle Proteins
6
2025
220
0.670
Why?
Adaptor Proteins, Signal Transducing
2
2017
399
0.660
Why?
Histone Deacetylase 6
6
2022
17
0.660
Why?
Mice, Knockout
12
2024
2871
0.650
Why?
NF-kappa B
11
2024
665
0.650
Why?
Calcium-Calmodulin-Dependent Protein Kinases
12
2006
181
0.630
Why?
NF-E2-Related Factor 2
1
2019
79
0.600
Why?
Calcineurin
12
2008
98
0.600
Why?
Pulmonary Artery
4
2021
1095
0.590
Why?
I-kappa B Proteins
8
2000
79
0.580
Why?
Myogenic Regulatory Factors
18
2009
56
0.580
Why?
T-Lymphocytes
6
2022
1933
0.570
Why?
Drug Discovery
2
2016
131
0.570
Why?
Oxidative Stress
3
2019
1266
0.560
Why?
Immunotherapy
1
2022
592
0.560
Why?
High-Throughput Screening Assays
2
2016
138
0.550
Why?
Models, Biological
15
2022
1722
0.550
Why?
Carrier Proteins
8
2013
742
0.550
Why?
Karyopherins
2
2009
19
0.550
Why?
Intracellular Signaling Peptides and Proteins
4
2019
442
0.540
Why?
Histone Acetyltransferases
3
2014
61
0.530
Why?
Muscle, Smooth, Vascular
5
2021
443
0.530
Why?
Extracellular Signal-Regulated MAP Kinases
2
2017
169
0.530
Why?
Male
53
2025
63512
0.520
Why?
Receptors, Cytoplasmic and Nuclear
4
2009
217
0.510
Why?
Fatty Liver
1
2018
230
0.500
Why?
Protein Binding
13
2019
2120
0.500
Why?
Alkaline Phosphatase
2
2017
146
0.490
Why?
Blood Pressure
6
2022
1736
0.490
Why?
Active Transport, Cell Nucleus
10
2010
113
0.490
Why?
Transforming Growth Factor beta
6
2021
455
0.490
Why?
Enzyme Inhibitors
6
2016
827
0.480
Why?
Transcription, Genetic
17
2014
1416
0.470
Why?
Microtubules
1
2017
263
0.470
Why?
Sumoylation
1
2014
16
0.460
Why?
Carbazoles
1
2015
84
0.460
Why?
Phosphodiesterase 5 Inhibitors
1
2014
37
0.460
Why?
Receptors, Endothelin
1
2014
50
0.460
Why?
SUMO-1 Protein
1
2014
20
0.460
Why?
Cardiotonic Agents
2
2014
126
0.450
Why?
MicroRNAs
4
2021
676
0.440
Why?
Pyrroles
1
2015
202
0.440
Why?
Muscular Atrophy
1
2014
71
0.430
Why?
YY1 Transcription Factor
2
2015
28
0.420
Why?
Phenotype
9
2025
3074
0.410
Why?
Stroke Volume
6
2025
592
0.400
Why?
Calcium
4
2023
1212
0.390
Why?
Myocardial Contraction
5
2023
335
0.390
Why?
Isoenzymes
7
2017
302
0.390
Why?
Enhancer Elements, Genetic
5
2024
176
0.380
Why?
Cardiovascular Agents
3
2025
156
0.380
Why?
Transcriptome
6
2025
874
0.370
Why?
Immunoblotting
5
2014
305
0.370
Why?
Troponin I
2
2023
75
0.360
Why?
Chromatin Assembly and Disassembly
2
2024
100
0.360
Why?
Myosin Heavy Chains
4
2010
170
0.350
Why?
Membrane Glycoproteins
2
2005
476
0.350
Why?
Connectin
2
2022
31
0.340
Why?
Stem Cell Transplantation
2
2021
164
0.340
Why?
Nuclear Localization Signals
1
2010
15
0.340
Why?
Benzamides
3
2019
207
0.330
Why?
RNA Polymerase II
3
2019
317
0.330
Why?
HEK293 Cells
4
2019
696
0.330
Why?
COS Cells
9
2010
186
0.330
Why?
Cell Line
17
2021
2779
0.330
Why?
Induced Pluripotent Stem Cells
3
2021
221
0.320
Why?
RNA-Binding Proteins
3
2021
387
0.310
Why?
Ventricular Function, Left
3
2025
527
0.310
Why?
Membrane Proteins
1
2015
1117
0.310
Why?
Cardiomyopathy, Dilated
4
2025
381
0.310
Why?
Protein Isoforms
4
2013
389
0.300
Why?
Chromatography, High Pressure Liquid
1
2010
580
0.290
Why?
Mitogen-Activated Protein Kinase 3
2
2022
151
0.290
Why?
Aortic Valve
3
2022
347
0.290
Why?
Inflammation Mediators
3
2021
505
0.280
Why?
Diabetes Mellitus, Type 2
1
2022
2439
0.280
Why?
Cardiomyopathies
2
2023
340
0.280
Why?
Amino Acid Sequence
12
2016
2056
0.280
Why?
Protein Kinase Inhibitors
2
2011
890
0.270
Why?
TRPC Cation Channels
1
2006
14
0.260
Why?
Cell Differentiation
8
2021
1887
0.260
Why?
Ankyrins
2
2005
9
0.260
Why?
Female
28
2025
68551
0.250
Why?
Hydrogels
3
2023
629
0.250
Why?
RNA, Messenger
9
2022
2703
0.250
Why?
GATA4 Transcription Factor
4
2020
18
0.250
Why?
Small Molecule Libraries
2
2016
86
0.240
Why?
Stress, Physiological
2
2006
414
0.240
Why?
Acetyltransferases
2
2002
21
0.240
Why?
Aging
2
2015
1774
0.240
Why?
Proteins
4
2021
941
0.240
Why?
Citalopram
1
2025
30
0.240
Why?
Primary Ovarian Insufficiency
1
2025
34
0.230
Why?
Protein Kinases
2
2007
318
0.230
Why?
Acylation
2
2022
28
0.230
Why?
Cortical Bone
2
2021
18
0.230
Why?
Cardiac Output, Low
1
2005
66
0.230
Why?
Calcium Signaling
4
2015
250
0.230
Why?
3T3-L1 Cells
2
2022
34
0.230
Why?
Estrogens
2
2020
346
0.230
Why?
MAP Kinase Signaling System
3
2021
313
0.230
Why?
Gene Expression Regulation, Developmental
4
2021
820
0.220
Why?
Cyclophilins
1
2024
41
0.220
Why?
Cardiomyopathy, Hypertrophic
2
2021
132
0.220
Why?
Sequence Analysis, RNA
3
2021
428
0.220
Why?
Uncoupling Protein 1
1
2023
15
0.220
Why?
Hypertension
3
2011
1242
0.220
Why?
Transforming Growth Factor beta1
2
2022
157
0.220
Why?
Mice, Transgenic
12
2023
2117
0.220
Why?
Adaptation, Physiological
4
2017
513
0.220
Why?
Autophagy
2
2017
266
0.210
Why?
Calcinosis
2
2017
231
0.210
Why?
Transcriptional Activation
7
2013
367
0.210
Why?
Hypoxia
5
2013
1084
0.210
Why?
Diet, High-Fat
3
2022
239
0.210
Why?
Reverse Transcriptase Polymerase Chain Reaction
5
2013
947
0.210
Why?
Genetic Therapy
1
2005
288
0.200
Why?
Arrhythmias, Cardiac
2
2017
317
0.200
Why?
Cell Communication
1
2024
300
0.200
Why?
Valproic Acid
2
2013
47
0.200
Why?
Acute Kidney Injury
2
2022
790
0.200
Why?
Inflammation
4
2017
2737
0.200
Why?
Endocardium
1
2022
33
0.200
Why?
Enzyme Activation
6
2022
812
0.200
Why?
Metalloproteases
1
2022
44
0.200
Why?
Molecular Sequence Data
13
2011
2835
0.200
Why?
Menopause
1
2025
297
0.190
Why?
NFATC Transcription Factors
6
2006
84
0.190
Why?
Cell Physiological Phenomena
1
2002
17
0.190
Why?
Macrophage Activation
2
2021
189
0.190
Why?
Cellular Senescence
1
2023
181
0.190
Why?
Matrix Metalloproteinases, Secreted
1
2021
12
0.190
Why?
Hemodynamics
2
2018
1090
0.190
Why?
Muscular Dystrophy, Duchenne
1
2023
89
0.190
Why?
Long Term Adverse Effects
1
2021
12
0.190
Why?
ADAMTS4 Protein
1
2021
16
0.190
Why?
Immunohistochemistry
4
2021
1691
0.190
Why?
Receptor, Platelet-Derived Growth Factor alpha
1
2022
45
0.190
Why?
Tyrosine 3-Monooxygenase
2
2001
71
0.190
Why?
Thiazepines
1
2021
6
0.190
Why?
Polymerase Chain Reaction
3
2013
1036
0.190
Why?
Proteomics
3
2025
1054
0.180
Why?
Homeodomain Proteins
2
2024
495
0.180
Why?
Saccharomyces cerevisiae Proteins
2
2002
383
0.180
Why?
Paracrine Communication
1
2021
61
0.180
Why?
Structure-Activity Relationship
6
2011
548
0.180
Why?
Ryanodine Receptor Calcium Release Channel
1
2021
71
0.180
Why?
Heart Rate
1
2025
802
0.180
Why?
Adenylate Kinase
3
2013
26
0.180
Why?
Proteome
1
2025
438
0.170
Why?
Naphthyridines
2
2010
16
0.170
Why?
Vasoconstrictor Agents
1
2021
127
0.170
Why?
Serine
5
2006
138
0.170
Why?
Drug Evaluation, Preclinical
2
2011
171
0.170
Why?
Exosomes
1
2021
96
0.170
Why?
Leptin
1
2022
219
0.170
Why?
RNA Interference
2
2013
450
0.170
Why?
Microscopy, Fluorescence
3
2009
398
0.170
Why?
Jumonji Domain-Containing Histone Demethylases
1
2020
60
0.170
Why?
Histone Deacetylase 2
3
2013
10
0.170
Why?
Machine Learning
1
2025
442
0.170
Why?
Catalytic Domain
3
2015
218
0.160
Why?
Aminopyridines
2
2010
97
0.160
Why?
Immunoglobulins
1
2000
160
0.160
Why?
Succinic Acid
1
2019
38
0.160
Why?
Protein Transport
3
2009
428
0.160
Why?
Diastole
1
2020
148
0.160
Why?
Histone Deacetylase 1
2
2017
24
0.160
Why?
Serum
1
2019
58
0.160
Why?
Reperfusion Injury
1
2022
272
0.160
Why?
Ventricular Function
1
2019
61
0.160
Why?
Oxadiazoles
1
2019
33
0.160
Why?
Biomimetics
1
2019
42
0.160
Why?
Energy Metabolism
3
2022
873
0.160
Why?
Phosphodiesterase 3 Inhibitors
1
2019
14
0.160
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
1
2021
274
0.160
Why?
Cardio-Renal Syndrome
1
2019
12
0.160
Why?
Pyrimidines
2
2013
459
0.150
Why?
Heart Failure, Diastolic
1
2019
21
0.150
Why?
Receptor Cross-Talk
1
2018
21
0.150
Why?
Wound Healing
1
2021
306
0.150
Why?
Cardiovascular Diseases
4
2025
2003
0.150
Why?
Cell Culture Techniques
1
2021
336
0.150
Why?
Histone Code
1
2018
31
0.150
Why?
Mitochondria, Heart
1
2019
94
0.150
Why?
Biopsy
1
2022
1092
0.150
Why?
3' Untranslated Regions
2
2016
137
0.150
Why?
Adipose Tissue, White
1
2018
37
0.150
Why?
p38 Mitogen-Activated Protein Kinases
1
2019
275
0.150
Why?
Middle Aged
11
2025
31090
0.150
Why?
Cell Adhesion Molecules
1
2019
173
0.150
Why?
Metal Nanoparticles
1
2019
81
0.150
Why?
Gold
1
2019
118
0.150
Why?
Myocardial Ischemia
1
2019
258
0.150
Why?
RNA, Small Interfering
3
2011
591
0.150
Why?
Case-Control Studies
3
2021
3377
0.140
Why?
Tumor Necrosis Factor-alpha
3
2017
1202
0.140
Why?
Amides
2
2009
91
0.140
Why?
Synovial Membrane
2
2016
90
0.140
Why?
Mitogen-Activated Protein Kinase 14
1
2017
6
0.140
Why?
Transcatheter Aortic Valve Replacement
1
2019
121
0.140
Why?
Protein Domains
1
2019
253
0.140
Why?
14-3-3 Proteins
3
2010
17
0.140
Why?
Adenoviridae
2
2011
192
0.140
Why?
Feedback, Physiological
1
2017
76
0.140
Why?
Metabolic Syndrome
1
2021
339
0.140
Why?
Mitochondrial Proteins
1
2019
248
0.140
Why?
Myosins
1
2018
133
0.140
Why?
NAV1.5 Voltage-Gated Sodium Channel
1
2017
12
0.140
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2
4
2008
185
0.140
Why?
Calcineurin Inhibitors
3
2004
68
0.140
Why?
JNK Mitogen-Activated Protein Kinases
1
2017
161
0.140
Why?
Human T-lymphotropic virus 1
2
1996
28
0.140
Why?
Down-Regulation
2
2016
636
0.140
Why?
Stem Cells
1
2021
574
0.140
Why?
Lymphocyte Activation
2
2000
1109
0.130
Why?
Gap Junctions
1
2017
61
0.130
Why?
Kidney
2
2022
1385
0.130
Why?
Tissue Scaffolds
1
2019
201
0.130
Why?
Tubulin
2
2015
137
0.130
Why?
Arthritis, Rheumatoid
2
2016
1097
0.130
Why?
Tryptophan Hydroxylase
1
2016
53
0.130
Why?
CapZ Actin Capping Protein
1
2016
2
0.130
Why?
Gene Knockdown Techniques
1
2017
316
0.130
Why?
Synoviocytes
1
2016
11
0.130
Why?
Gene Products, tat
1
1996
21
0.130
Why?
Transcription Elongation, Genetic
1
2016
22
0.130
Why?
Transcription Initiation Site
1
2016
43
0.130
Why?
Cell Movement
4
2015
944
0.130
Why?
Reactive Oxygen Species
1
2019
596
0.130
Why?
Pyridines
2
2012
478
0.130
Why?
RNA, Long Noncoding
1
2018
179
0.130
Why?
Serum Response Factor
1
2016
31
0.130
Why?
Molecular Imaging
1
2016
55
0.130
Why?
Binding Sites
6
2008
1250
0.120
Why?
Cellular Reprogramming Techniques
1
2015
11
0.120
Why?
Ischemia
1
2019
406
0.120
Why?
Reproducibility of Results
3
2019
3080
0.120
Why?
Hypertrophy
3
2023
121
0.120
Why?
Positron-Emission Tomography
1
2017
286
0.120
Why?
Cell Cycle
2
2019
589
0.120
Why?
MyoD Protein
4
2002
32
0.120
Why?
Osteogenesis
1
2017
172
0.120
Why?
Interleukins
1
2017
241
0.120
Why?
Tissue Engineering
1
2019
388
0.120
Why?
Ventricular Function, Right
1
2017
276
0.120
Why?
rho-Associated Kinases
1
2015
87
0.120
Why?
Chagas Cardiomyopathy
1
2015
22
0.120
Why?
Cellular Reprogramming
1
2015
95
0.120
Why?
PTEN Phosphohydrolase
1
2016
161
0.120
Why?
Promoter Regions, Genetic
5
2016
1204
0.110
Why?
Transcription Factor CHOP
1
2014
30
0.110
Why?
Biocatalysis
1
2014
68
0.110
Why?
Endopeptidases
1
2014
86
0.110
Why?
Positive Transcriptional Elongation Factor B
1
2014
29
0.110
Why?
Aortic Valve Stenosis
1
2017
218
0.110
Why?
Superoxide Dismutase
1
2016
342
0.110
Why?
Systole
1
2014
191
0.110
Why?
Transfection
8
2015
915
0.110
Why?
Physical Exertion
1
2014
205
0.110
Why?
Estrogen Receptor beta
1
2013
38
0.110
Why?
Gonadotropin-Releasing Hormone
1
2015
204
0.110
Why?
Interleukin-1beta
3
2024
372
0.100
Why?
Phosphoproteins
3
2001
332
0.100
Why?
Proto-Oncogene Proteins c-akt
1
2015
431
0.100
Why?
Mitogen-Activated Protein Kinase 1
1
2013
184
0.100
Why?
Protein Biosynthesis
1
2014
405
0.100
Why?
Recombinant Proteins
7
2017
1304
0.100
Why?
Membrane Transport Proteins
1
2013
149
0.100
Why?
Endothelin-1
2
2011
179
0.100
Why?
Endoplasmic Reticulum
1
2014
261
0.090
Why?
Retroviridae Proteins, Oncogenic
3
1997
10
0.090
Why?
Tumor Suppressor Proteins
1
2014
314
0.090
Why?
Vascular Diseases
1
2014
240
0.090
Why?
Adrenergic beta-1 Receptor Agonists
1
2011
5
0.090
Why?
Azoles
1
2011
4
0.090
Why?
Indoles
1
2014
384
0.090
Why?
Receptors, Adrenergic, alpha-1
1
2011
43
0.090
Why?
Cell Size
2
2016
87
0.090
Why?
Cats
2
2022
207
0.090
Why?
2,2'-Dipyridyl
1
2010
6
0.090
Why?
Dose-Response Relationship, Drug
3
2022
2011
0.090
Why?
Rats, Inbred Dahl
3
2020
8
0.090
Why?
Kinetics
4
2006
1644
0.090
Why?
Single-Cell Analysis
2
2024
275
0.090
Why?
Norepinephrine
1
2011
210
0.090
Why?
Cyclic AMP-Dependent Protein Kinases
1
2011
132
0.080
Why?
Heart Defects, Congenital
1
2017
757
0.080
Why?
Estradiol
1
2013
494
0.080
Why?
Saccharomyces cerevisiae
3
2005
530
0.080
Why?
Consensus Sequence
1
2010
73
0.080
Why?
Electrophoresis, Polyacrylamide Gel
1
2010
327
0.080
Why?
Insulin Resistance
1
2018
1165
0.080
Why?
Molecular Structure
2
2011
481
0.080
Why?
Flow Cytometry
1
2013
1155
0.080
Why?
Atrial Natriuretic Factor
3
2004
56
0.080
Why?
Regional Blood Flow
1
2012
463
0.080
Why?
Mutation
6
2014
3710
0.080
Why?
Models, Animal
1
2011
376
0.080
Why?
Immunoprecipitation
1
2009
157
0.080
Why?
Aged
5
2025
22032
0.080
Why?
Protein Interaction Mapping
1
2010
108
0.080
Why?
Embryo, Mammalian
3
2020
224
0.080
Why?
Cytokines
2
2014
2013
0.080
Why?
Cell Survival
3
2015
1075
0.080
Why?
Cattle
4
2013
977
0.080
Why?
Precipitin Tests
3
2004
97
0.080
Why?
Phenylephrine
2
2021
75
0.080
Why?
NF-KappaB Inhibitor alpha
5
2000
53
0.080
Why?
Immunologic Factors
1
2011
230
0.080
Why?
Aniline Compounds
1
2009
97
0.080
Why?
Muscle Fibers, Skeletal
2
2020
187
0.070
Why?
Adult
8
2019
35495
0.070
Why?
Drug Design
1
2009
156
0.070
Why?
Renal Insufficiency, Chronic
1
2014
566
0.070
Why?
Organ Culture Techniques
2
2019
153
0.070
Why?
Cyclosporine
2
1999
263
0.070
Why?
Piperazines
1
2010
341
0.070
Why?
Swine
2
2021
760
0.070
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2007
28
0.070
Why?
Proto-Oncogene Proteins
3
1996
635
0.070
Why?
Muscle Fatigue
1
2008
99
0.070
Why?
Substrate Specificity
2
2006
368
0.070
Why?
Diet
1
2014
1212
0.070
Why?
Aged, 80 and over
1
2018
7055
0.070
Why?
Neovascularization, Physiologic
1
2008
175
0.070
Why?
Rats, Inbred WF
1
2006
8
0.070
Why?
Cocaine-Related Disorders
1
2007
108
0.070
Why?
Thiadiazoles
1
2006
24
0.060
Why?
Rats, Inbred SHR
1
2006
44
0.060
Why?
Cell Transformation, Neoplastic
2
2000
327
0.060
Why?
Neurons
1
2015
1494
0.060
Why?
Apoptosis
4
2021
2499
0.060
Why?
Biological Transport
2
2013
404
0.060
Why?
Drug Delivery Systems
1
2009
333
0.060
Why?
Inositol 1,4,5-Trisphosphate
1
2006
31
0.060
Why?
Anilides
1
2006
72
0.060
Why?
Transcription Factor RelA
2
2024
83
0.060
Why?
Kidney Diseases
1
2010
382
0.060
Why?
Nuclear Envelope
1
2006
28
0.060
Why?
Adenosine Diphosphate
1
2006
80
0.060
Why?
Models, Genetic
3
2004
593
0.060
Why?
Gene Deletion
3
2017
380
0.060
Why?
Protein Structure, Tertiary
2
2008
841
0.060
Why?
Pneumonia
1
2011
616
0.060
Why?
Base Sequence
6
2006
2146
0.060
Why?
Vinyl Compounds
1
2025
6
0.060
Why?
Cyclohexenes
1
2025
7
0.060
Why?
Models, Anatomic
1
2006
89
0.060
Why?
Receptors, Cell Surface
1
2007
380
0.060
Why?
Vascular Endothelial Growth Factor A
1
2008
530
0.060
Why?
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
1
2025
33
0.060
Why?
CX3C Chemokine Receptor 1
1
2024
19
0.060
Why?
Fluoresceins
1
2004
47
0.060
Why?
Research Design
2
2022
1043
0.060
Why?
Adhesins, Bacterial
1
2004
40
0.060
Why?
Potassium Channels
1
2025
149
0.060
Why?
Chromatin Immunoprecipitation
2
2015
132
0.060
Why?
Administration, Oral
3
2011
785
0.050
Why?
Metabolomics
2
2019
652
0.050
Why?
Time Factors
1
2014
6543
0.050
Why?
Adenosine Triphosphate
1
2006
478
0.050
Why?
Real-Time Polymerase Chain Reaction
2
2015
328
0.050
Why?
Green Fluorescent Proteins
1
2004
385
0.050
Why?
NG-Nitroarginine Methyl Ester
1
2023
48
0.050
Why?
Jurkat Cells
2
2000
134
0.050
Why?
Fluorescent Dyes
1
2004
312
0.050
Why?
Methylation
2
2019
230
0.050
Why?
Tyrosine
1
2023
223
0.050
Why?
Cell Division
2
2002
796
0.050
Why?
Action Potentials
2
2017
485
0.050
Why?
Adrenergic beta-Antagonists
1
2025
321
0.050
Why?
Carbamates
1
2023
46
0.050
Why?
Sex Factors
2
2022
1965
0.050
Why?
Protein-Arginine N-Methyltransferases
1
2002
28
0.050
Why?
Protein-Tyrosine Kinases
2
2023
432
0.050
Why?
Sex Characteristics
2
2019
736
0.050
Why?
Enzyme-Linked Immunosorbent Assay
1
2004
833
0.050
Why?
Massachusetts
1
2022
159
0.050
Why?
Mice, Obese
1
2022
59
0.050
Why?
Nuclear Receptor Coactivator 2
1
2001
2
0.050
Why?
Gene Expression
4
2016
1466
0.050
Why?
RNA, Small Nucleolar
1
2021
8
0.050
Why?
Chromosomal Proteins, Non-Histone
1
2002
116
0.050
Why?
Nuclear Receptor Co-Repressor 2
1
2001
15
0.050
Why?
Rats, Transgenic
1
2021
18
0.050
Why?
Rats, Inbred BN
1
2021
59
0.050
Why?
p300-CBP Transcription Factors
1
2001
20
0.050
Why?
Swine, Miniature
1
2021
81
0.050
Why?
Embryonic and Fetal Development
1
2001
95
0.050
Why?
Sequence Deletion
1
2001
179
0.040
Why?
Muscle Development
1
2001
103
0.040
Why?
American Heart Association
1
2022
296
0.040
Why?
Blotting, Western
2
2015
1204
0.040
Why?
Cytoplasm
3
2015
265
0.040
Why?
Culture Media
1
2021
160
0.040
Why?
DNA Primers
3
1996
510
0.040
Why?
B-Lymphocytes
1
2006
815
0.040
Why?
Peptides
1
2006
923
0.040
Why?
Receptors, Antigen, T-Cell
1
2004
704
0.040
Why?
Double-Blind Method
1
2025
1875
0.040
Why?
Muscle Cells
2
2010
42
0.040
Why?
Cell Death
1
2002
354
0.040
Why?
Mutagenesis
1
2000
181
0.040
Why?
Genes, ras
1
2000
96
0.040
Why?
Genetic Engineering
1
2000
86
0.040
Why?
Lung
3
2020
3927
0.040
Why?
Serotonin
2
2016
318
0.040
Why?
Stress, Psychological
1
2007
1066
0.040
Why?
Cyclic Nucleotide Phosphodiesterases, Type 3
1
2019
10
0.040
Why?
Pregnancy
2
2022
6390
0.040
Why?
Pharmacogenomic Testing
1
2019
61
0.040
Why?
Coculture Techniques
1
2019
223
0.040
Why?
Sequence Homology, Amino Acid
3
2008
372
0.040
Why?
Hypertrophy, Left Ventricular
1
1999
126
0.040
Why?
RNA
1
2004
880
0.040
Why?
Cyclic AMP
1
2019
237
0.040
Why?
Glomerular Filtration Rate
1
2022
711
0.040
Why?
Antibodies, Monoclonal
1
2004
1367
0.040
Why?
Fatty Acids
1
2021
427
0.040
Why?
Antigens, CD
1
2000
489
0.040
Why?
Congresses as Topic
1
2019
216
0.040
Why?
Body Weight
1
2022
939
0.030
Why?
Materials Testing
1
2019
343
0.030
Why?
Fluorine Radioisotopes
1
2017
11
0.030
Why?
Autoradiography
1
2017
73
0.030
Why?
Papio
1
2017
91
0.030
Why?
Tissue Donors
1
2019
391
0.030
Why?
Bone Morphogenetic Protein 2
1
2017
63
0.030
Why?
Enzyme Repression
1
2016
6
0.030
Why?
Antihypertensive Agents
2
2010
485
0.030
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 4
3
2000
7
0.030
Why?
Protein Kinase C-epsilon
1
2016
26
0.030
Why?
Radiopharmaceuticals
1
2017
168
0.030
Why?
STAT1 Transcription Factor
1
2016
70
0.030
Why?
Cysteine Endopeptidases
1
1996
68
0.030
Why?
Multienzyme Complexes
1
1996
68
0.030
Why?
Interferon-beta
1
2016
89
0.030
Why?
Recombinant Fusion Proteins
3
2004
648
0.030
Why?
Polymorphism, Genetic
1
2019
639
0.030
Why?
Echocardiography
1
2019
629
0.030
Why?
DNA Methylation
1
2020
610
0.030
Why?
Metabolome
1
2019
338
0.030
Why?
Collagen Type III
1
2015
14
0.030
Why?
Proteasome Endopeptidase Complex
1
1996
148
0.030
Why?
Models, Molecular
2
2010
1487
0.030
Why?
Lymphocytes
1
1997
378
0.030
Why?
Interferon Regulatory Factor-1
1
2014
13
0.030
Why?
Cardiomegaly, Exercise-Induced
1
2014
3
0.030
Why?
Matrix Metalloproteinase 1
1
2014
18
0.030
Why?
Clathrin
1
1995
26
0.030
Why?
Blood Sedimentation
1
2014
34
0.030
Why?
Viral Proteins
1
1997
327
0.030
Why?
Muscle Fibers, Slow-Twitch
2
2008
10
0.030
Why?
Soybean Proteins
1
2014
14
0.030
Why?
T-Box Domain Proteins
1
2015
96
0.030
Why?
Acetyl-CoA Carboxylase
1
2014
33
0.030
Why?
Caseins
1
2014
18
0.030
Why?
Gene Regulatory Networks
1
2017
280
0.030
Why?
Trypanosoma cruzi
1
2015
25
0.030
Why?
Ketocholesterols
1
2014
7
0.030
Why?
alpha-Crystallin B Chain
1
2014
24
0.030
Why?
Cytoskeletal Proteins
1
2015
146
0.030
Why?
Ezetimibe
1
2014
25
0.030
Why?
Microfilament Proteins
1
2015
128
0.030
Why?
Azetidines
1
2014
40
0.030
Why?
Microscopy, Electron
1
2014
426
0.030
Why?
Gene Silencing
1
2015
190
0.030
Why?
Simvastatin
1
2014
60
0.030
Why?
Apolipoproteins E
1
2014
77
0.030
Why?
Primary Cell Culture
1
2014
160
0.030
Why?
Gene Expression Profiling
1
2021
1688
0.030
Why?
Actins
1
2016
411
0.030
Why?
Polypyrimidine Tract-Binding Protein
1
2013
17
0.030
Why?
Isoquinolines
1
2013
41
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
74
0.030
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2015
235
0.030
Why?
Mitochondria
1
2020
877
0.030
Why?
Protein Kinase C-delta
1
2013
44
0.030
Why?
Blood-Retinal Barrier
1
2013
14
0.030
Why?
Calmodulin
2
2006
76
0.030
Why?
Receptor, Notch1
1
2013
61
0.030
Why?
Liver
1
2022
1839
0.030
Why?
Chemokine CCL2
1
2013
118
0.030
Why?
AMP-Activated Protein Kinases
1
2014
191
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2013
117
0.030
Why?
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
1
2013
41
0.030
Why?
Retroviridae
1
1993
99
0.030
Why?
Familial Primary Pulmonary Hypertension
1
2013
199
0.030
Why?
Forkhead Transcription Factors
1
2013
184
0.030
Why?
C-Reactive Protein
1
2014
400
0.020
Why?
Rats, Wistar
1
2013
441
0.020
Why?
Platelet-Derived Growth Factor
1
2012
89
0.020
Why?
Sequence Alignment
2
2004
332
0.020
Why?
Up-Regulation
1
2015
839
0.020
Why?
Mice, Inbred BALB C
1
2015
1247
0.020
Why?
Oncogene Proteins v-rel
3
1997
3
0.020
Why?
Genes, Reporter
2
2004
265
0.020
Why?
Connective Tissue
1
2011
37
0.020
Why?
Proto-Oncogene Proteins c-rel
3
1996
9
0.020
Why?
Chick Embryo
3
1997
130
0.020
Why?
ErbB Receptors
1
1995
605
0.020
Why?
Aorta, Thoracic
2
2007
262
0.020
Why?
Drug Therapy, Combination
1
2014
1040
0.020
Why?
Cell Line, Transformed
2
2002
140
0.020
Why?
Molecular Targeted Therapy
1
2014
390
0.020
Why?
Retina
1
2013
277
0.020
Why?
Nerve Tissue Proteins
1
1995
569
0.020
Why?
DNA, Viral
1
1993
349
0.020
Why?
Inhibitory Concentration 50
1
2011
86
0.020
Why?
Biological Availability
1
2011
147
0.020
Why?
Fluorescent Antibody Technique
1
2011
376
0.020
Why?
Treatment Outcome
1
2025
10202
0.020
Why?
Lipids
1
2014
625
0.020
Why?
Atherosclerosis
1
2014
402
0.020
Why?
Cell Adhesion
1
2011
452
0.020
Why?
MADS Domain Proteins
1
2009
5
0.020
Why?
Neoplasms
1
2004
2449
0.020
Why?
Colorado
1
2019
4406
0.020
Why?
Monocytes
1
2011
551
0.020
Why?
Genetic Predisposition to Disease
1
2017
2276
0.020
Why?
Phospholipase C gamma
1
2008
29
0.020
Why?
Phosphoserine
1
2008
34
0.020
Why?
Protein Structure, Quaternary
1
2008
122
0.020
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2008
84
0.020
Why?
Dopamine Uptake Inhibitors
1
2007
55
0.020
Why?
Brain
1
1999
2669
0.020
Why?
Multiprotein Complexes
1
2008
155
0.020
Why?
Severity of Illness Index
1
2014
2740
0.020
Why?
Nucleus Accumbens
1
2007
126
0.020
Why?
Inositol 1,4,5-Trisphosphate Receptors
1
2006
31
0.020
Why?
Cocaine
1
2007
149
0.020
Why?
Chickens
1
2006
189
0.020
Why?
DNA, Complementary
1
2006
271
0.020
Why?
United States
1
2022
13826
0.020
Why?
Reward
1
2007
240
0.020
Why?
Receptors, Antigen, B-Cell
1
2006
126
0.010
Why?
Nuclear Receptor Subfamily 4, Group A, Member 1
1
2004
12
0.010
Why?
Calcium Channels
1
2006
164
0.010
Why?
DNA
2
2003
1396
0.010
Why?
Receptors, Steroid
1
2004
50
0.010
Why?
Rabbits
1
2006
777
0.010
Why?
Thymus Gland
1
2004
308
0.010
Why?
Infant
1
2017
8975
0.010
Why?
Fluorescent Antibody Technique, Indirect
1
2003
48
0.010
Why?
Tritium
1
2003
75
0.010
Why?
Ventricular Myosins
1
2003
36
0.010
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 1
1
2002
3
0.010
Why?
Phosphotransferases
1
2002
24
0.010
Why?
Leucine
1
2003
108
0.010
Why?
Endothelial Cells
1
2008
746
0.010
Why?
Emotions
1
2007
538
0.010
Why?
Glycogen Synthase Kinases
1
2002
3
0.010
Why?
Methyltransferases
1
2002
70
0.010
Why?
Oligonucleotide Array Sequence Analysis
1
2004
756
0.010
Why?
Glycogen Synthase Kinase 3
1
2002
79
0.010
Why?
Chronic Disease
1
2007
1716
0.010
Why?
Isoproterenol
1
2002
115
0.010
Why?
Chromosome Mapping
1
2002
504
0.010
Why?
Two-Hybrid System Techniques
1
2001
56
0.010
Why?
Histone-Lysine N-Methyltransferase
1
2002
124
0.010
Why?
Thyroid Hormones
1
2000
55
0.010
Why?
Macromolecular Substances
1
2001
216
0.010
Why?
Alcohol Oxidoreductases
1
2001
60
0.010
Why?
Muscle Fibers, Fast-Twitch
1
2000
10
0.010
Why?
Amino Acid Motifs
1
2001
213
0.010
Why?
Luciferases
1
2000
147
0.010
Why?
Young Adult
1
2016
12391
0.010
Why?
Exons
1
2000
341
0.010
Why?
Expressed Sequence Tags
1
1999
41
0.010
Why?
Organ Specificity
1
2000
295
0.010
Why?
Electric Stimulation
1
2000
269
0.010
Why?
Zinc Fingers
1
1999
45
0.010
Why?
Ligation
1
1999
87
0.010
Why?
Aorta, Abdominal
1
1999
43
0.010
Why?
In Situ Hybridization
1
1999
296
0.010
Why?
Testis
1
1999
144
0.010
Why?
Fetus
1
2003
770
0.010
Why?
Tissue Distribution
1
1999
315
0.010
Why?
Adolescent
1
2017
20313
0.010
Why?
Cloning, Molecular
1
1999
525
0.010
Why?
Mice, Nude
1
2000
682
0.010
Why?
Motor Neurons
1
2000
236
0.010
Why?
Inhibitor of Apoptosis Proteins
1
1997
45
0.010
Why?
Child
1
2017
20785
0.010
Why?
Disease Susceptibility
1
1999
333
0.010
Why?
Proto-Oncogenes
1
1996
29
0.010
Why?
Restriction Mapping
1
1996
75
0.010
Why?
Aorta
1
1999
408
0.010
Why?
Oligodeoxyribonucleotides
1
1996
140
0.010
Why?
src Homology Domains
1
1996
37
0.010
Why?
Sequence Analysis, DNA
1
1999
776
0.010
Why?
Gene Products, tax
1
1995
13
0.010
Why?
Intestinal Mucosa
1
2000
589
0.010
Why?
3T3 Cells
1
1995
153
0.010
Why?
Adaptor Proteins, Vesicular Transport
1
1995
43
0.010
Why?
Tumor Cells, Cultured
1
1996
942
0.010
Why?
Mutagenesis, Site-Directed
1
1995
361
0.010
Why?
Databases, Factual
1
1999
1266
0.010
Why?
Transcription Factor RelB
1
1993
4
0.010
Why?
Cell Transformation, Viral
1
1993
27
0.010
Why?
Antibodies
1
1995
398
0.010
Why?
Peptide Fragments
1
1996
692
0.010
Why?
Birds
1
1993
86
0.010
Why?
Spleen
1
1993
506
0.010
Why?
HIV-1
1
1995
836
0.000
Why?
Gene Expression Regulation, Neoplastic
1
1993
1344
0.000
Why?
McKinsey's Networks
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