 Histone Deacetylase 1
"Histone Deacetylase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 2; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7 as core components of histone deacetylase complexes.
| Descriptor ID |
D056284
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| MeSH Number(s) |
D08.811.277.087.520.500.100 D08.811.277.087.520.750.100 D08.811.600.620.100 D08.811.600.795.100
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| Concept/Terms |
Histone Deacetylase 1- Histone Deacetylase 1
- Deacetylase 1, Histone
- HDAC1 Histone Deacetylase
- Deacetylase, HDAC1 Histone
- Histone Deacetylase, HDAC1
- RPD3L1 Histone Deacetylase
- Deacetylase, RPD3L1 Histone
- Histone Deacetylase, RPD3L1
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Below are MeSH descriptors whose meaning is more general than "Histone Deacetylase 1".
Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylase 1".
This graph shows the total number of publications written about "Histone Deacetylase 1" by people in this website by year, and whether "Histone Deacetylase 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 2 | 3 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histone Deacetylase 1" by people in Profiles.
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Ebot-Ojong F, Ferraro AR, Yap RE, Kaddar F, Hull-Crew C, Scadden AW, Deaven AM, Klocko AD, Lewis ZA. HISTONE DEACETYLASE-1 is required for epigenome stability in Neurospora crassa. Proc Natl Acad Sci U S A. 2025 Oct 07; 122(40):e2503876122.
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Dunaway LS, Cook AK, Kellum CE, Edell C, Botta D, Molina PA, Sedaka RS, d'Uscio LV, Katusic ZS, Pollock DM, Inscho EW, Pollock JS. Endothelial histone deacetylase 1 activity impairs kidney microvascular NO signaling in rats fed a high-salt diet. Acta Physiol (Oxf). 2024 09; 240(9):e14201.
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Zhang Y, Remillard D, Onubogu U, Karakyriakou B, Asiaban JN, Ramos AR, Bowland K, Bishop TR, Barta PA, Nance S, Durbin AD, Ott CJ, Janiszewska M, Cravatt BF, Erb MA. Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities. Nat Struct Mol Biol. 2023 08; 30(8):1160-1171.
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Diamond JR, Pitts TM, Ungermannova D, Nasveschuk CG, Zhang G, Phillips AJ, Bagby SM, Pafford J, Yacob BW, Newton TP, Tentler JJ, Gittleman B, Hartman SJ, DeMattei JA, Winkler JD, Wendt MK, Schiemann WP, Eckhardt SG, Liu X, Piscopio AD. Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors. Mol Cancer Ther. 2022 03 01; 21(3):397-406.
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Sedaka R, Hyndman KA, Mironova E, Stockand JD, Pollock JS. High salt intake induces collecting duct HDAC1-dependent NO signaling. Am J Physiol Renal Physiol. 2021 03 01; 320(3):F297-F307.
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Hyndman KA, Speed JS, Mendoza LD, Allan JM, Colson J, Sedaka R, Jin C, Jung HJ, El-Dahr S, Pollock DM, Pollock JS. Fluid-electrolyte homeostasis requires histone deacetylase function. JCI Insight. 2020 08 20; 5(16).
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Li Y, Stockton ME, Eisinger BE, Zhao Y, Miller JL, Bhuiyan I, Gao Y, Wu Z, Peng J, Zhao X. Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome. Nat Commun. 2018 06 27; 9(1):2494.
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Tencer AH, Cox KL, Di L, Bridgers JB, Lyu J, Wang X, Sims JK, Weaver TM, Allen HF, Zhang Y, Gatchalian J, Darcy MA, Gibson MD, Ikebe J, Li W, Wade PA, Hayes JJ, Strahl BD, Kono H, Poirier MG, Musselman CA, Kutateladze TG. Covalent Modifications of Histone H3K9 Promote Binding of CHD3. Cell Rep. 2017 Oct 10; 21(2):455-466.
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Zhu Y, Vidaurre OG, Adula KP, Kezunovic N, Wentling M, Huntley GW, Casaccia P. Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation. J Neurosci. 2017 08 02; 37(31):7547-7559.
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Cadoni E, Marongiu F, Fanti M, Serra M, Laconi E. Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. Oncotarget. 2017 May 30; 8(22):36020-36032.
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