 Nuclear Receptor Coactivator 2
"Nuclear Receptor Coactivator 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that partners with ligand bound GLUCOCORTICOID RECEPTORS and ESTROGEN RECEPTORS to stimulate GENETIC TRANSCRIPTION. It plays an important role in FERTILITY as well as in METABOLISM of LIPIDS.
| Descriptor ID |
D051958
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| MeSH Number(s) |
D12.644.360.024.314.200 D12.776.157.057.080.200 D12.776.476.024.394.200 D12.776.660.675.200 D12.776.930.617.200
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| Concept/Terms |
Nuclear Receptor Coactivator 2- Nuclear Receptor Coactivator 2
- Steroid Receptor Coactivator SRC2
- Transcription Intermediary Factor 2
- Steroid Receptor Coactivator-2
- Steroid Receptor Coactivator 2
- Glucocorticoid Receptor-Interacting Protein 1
- Glucocorticoid Receptor Interacting Protein 1
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivator 2".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivator 2".
This graph shows the total number of publications written about "Nuclear Receptor Coactivator 2" by people in this website by year, and whether "Nuclear Receptor Coactivator 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivator 2" by people in Profiles.
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Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O'Malley BW, Lydon JP. Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics Reproduction. 2018 10 16; 156(5):387-395.
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Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BW. Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134.
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Camden AJ, Szwarc MM, Chadchan SB, DeMayo FJ, O'Malley BW, Lydon JP, Kommagani R. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
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Zhang X, Peng D, Xi Y, Yuan C, Sagum CA, Klein BJ, Tanaka K, Wen H, Kutateladze TG, Li W, Bedford MT, Shi X. G9a-mediated methylation of ERa links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression. Nat Commun. 2016 Mar 10; 7:10810.
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Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664.
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Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod. 2014 Apr; 90(4):75.
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Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900.
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