 DNA Methylation
"DNA Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
| Descriptor ID |
D019175
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| MeSH Number(s) |
G02.111.035.538.161 G02.111.218 G03.059.538.161 G05.206
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| Concept/Terms |
DNA Methylation- DNA Methylation
- DNA Methylations
- Methylation, DNA
- Methylations, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Methylation".
Below are MeSH descriptors whose meaning is more specific than "DNA Methylation".
This graph shows the total number of publications written about "DNA Methylation" by people in this website by year, and whether "DNA Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 2 | 3 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 1 | 4 | | 2004 | 1 | 0 | 1 | | 2005 | 2 | 1 | 3 | | 2006 | 2 | 3 | 5 | | 2007 | 1 | 3 | 4 | | 2008 | 5 | 8 | 13 | | 2009 | 2 | 7 | 9 | | 2010 | 4 | 6 | 10 | | 2011 | 5 | 9 | 14 | | 2012 | 8 | 7 | 15 | | 2013 | 10 | 4 | 14 | | 2014 | 4 | 11 | 15 | | 2015 | 18 | 9 | 27 | | 2016 | 10 | 13 | 23 | | 2017 | 15 | 13 | 28 | | 2018 | 12 | 9 | 21 | | 2019 | 14 | 11 | 25 | | 2020 | 15 | 12 | 27 | | 2021 | 11 | 15 | 26 | | 2022 | 4 | 17 | 21 | | 2023 | 11 | 8 | 19 | | 2024 | 23 | 7 | 30 | | 2025 | 11 | 5 | 16 |
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Below are the most recent publications written about "DNA Methylation" by people in Profiles.
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Vanderlinden LA, Wong E, Johnson RK, Carry P, Dong F, Kechris K, Rewers M, Norris JM. DNA Methylation Smoking Scores and Risk of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2025 Sep 01; 48(9):1628-1636.
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Hren A, Alexander WG, Abraham JP, Tumen-Velasquez MP, Melesse Vergara M, Guss AM, Pfleger BF, Fox JM, Eckert CA. Improving the Transformation Efficiency of Synechococcus sp. PCC 7002 via Methylome-Guided Premethylation of DNA. ACS Synth Biol. 2025 Aug 15; 14(8):3258-3264.
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Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole SA, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J. DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. Circulation. 2025 Aug 19; 152(7):436-449.
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Nidadavolu LS, Sosnowski DW, Sivakumar N, Merino Gomez A, Wu Y, Laskow T, Bopp T, Milcik N, Le A, Zhang C, Khare P, Zammit A, Grodstein F, Walston JD, Bennett DA, Mathias RA, Phillip JM, Maher BS, Oh ES, Abadir PM. Cardiovascular-Derived Circulating Cell-Free DNA Fragments Are Associated With Frailty and Increased Cardiovascular Events in Older Adults. J Gerontol A Biol Sci Med Sci. 2025 Jun 10; 80(7).
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Goyne C, Fair AE, Yilmaz D, Race J, Schuette A, Caillier SJ, Aaen GS, Abrams AW, Benson LA, Casper TC, Chitnis T, Gorman MP, Lotze TE, Krupp LB, Mar SS, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner TL, Tillema JM, Waldman AT, Wheeler YS, Barcellos LF, Waubant E, Graves JS. Epigenetic Aging in Pediatric-Onset Multiple Sclerosis. Neurology. 2025 Jun 24; 104(12):e213673.
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Kirmani S, Huan T, Van Amburg JC, Joehanes R, Uddin MM, Nguyen NQH, Yu B, Brody JA, Fornage M, Bressler J, Sotoodehnia N, Ong DA, Puddu F, Floyd JS, Ballantyne CM, Psaty BM, Raffield LM, Natarajan P, Conneely KN, Weinstock JS, Carson AP, Lange LA, Ferrier K, Heard-Costa NL, Murabito J, Bick AG, Levy D. Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Lundin JI, Peters U, Hu Y, Ammous F, Benjamin EJ, Bis JC, Brody JA, Cushman M, Fuller H, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lappalainen T, Levy D, Liu C, Liu Y, Loos RJF, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Ye T, Zhao W, Raffield LM, Kooperberg C. Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease. Atherosclerosis. 2025 Aug; 407:120219.
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Guerin LN, Scott TJ, Yap JA, Johansson A, Puddu F, Charlesworth T, Yang Y, Simmons AJ, Lau KS, Ihrie RA, Hodges E. Temporally discordant chromatin accessibility and DNA demethylation define short- and long-term enhancer regulation during cell fate specification. Cell Rep. 2025 May 27; 44(5):115680.
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Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Egan G, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs. Nature. 2025 Jun; 642(8067):421-430.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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