 Interleukin-1beta
"Interleukin-1beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.
| Descriptor ID |
D053583
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| MeSH Number(s) |
D12.644.276.374.465.010.600 D12.644.276.374.500.400.600 D12.776.467.374.465.010.600 D12.776.467.374.500.400.600 D23.529.374.465.131.600 D23.529.374.500.400.600
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| Concept/Terms |
Interleukin-1beta- Interleukin-1beta
- Interleukin 1beta
- IL-1 beta
- Interleukin-1 beta
- Interleukin 1 beta
- Catabolin
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1beta".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1beta".
This graph shows the total number of publications written about "Interleukin-1beta" by people in this website by year, and whether "Interleukin-1beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 2 | 4 | | 2007 | 10 | 3 | 13 | | 2008 | 5 | 5 | 10 | | 2009 | 11 | 6 | 17 | | 2010 | 8 | 6 | 14 | | 2011 | 9 | 16 | 25 | | 2012 | 9 | 8 | 17 | | 2013 | 10 | 11 | 21 | | 2014 | 9 | 12 | 21 | | 2015 | 2 | 10 | 12 | | 2016 | 0 | 10 | 10 | | 2017 | 2 | 10 | 12 | | 2018 | 4 | 12 | 16 | | 2019 | 2 | 9 | 11 | | 2020 | 1 | 9 | 10 | | 2021 | 5 | 5 | 10 | | 2023 | 1 | 2 | 3 | | 2024 | 0 | 4 | 4 | | 2025 | 1 | 5 | 6 | | 2026 | 0 | 3 | 3 |
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Below are the most recent publications written about "Interleukin-1beta" by people in Profiles.
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Zlotnick HM, Goddard DN, Calo CJ, Dhand AP, Davidson MD, Solsona-Pujol A, Makhoul JT, Weppner HK, Wong M, Scanzello CR, Hind LE, Burdick JA. Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model. Proc Natl Acad Sci U S A. 2026 May 19; 123(20):e2524677123.
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Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026 May; 653(8116):1184-1195.
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Hossen F, Kouwaki T, Fujiwara Y, Tsutsuki H, Zhang T, Guo C, Rahman A, Komohara Y, Oshiumi H, Sawa T. Therapeutic Efficacy of the Supersulfide Donor NAC-S2 in Influenza Virus Pneumonia via Suppression of Excessive Inflammatory Responses. Microbiol Immunol. 2026 Mar; 70(3):148-159.
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Necker-Brown A, Mostafa MM, Georgescu A, Thorne AJ, Chandramohan P, Kooi C, Kalyanaraman K, Gao A, Bansal A, Sasse SK, Gerber AN, Leigh R, Newton R. Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-?B. PLoS One. 2025; 20(12):e0329244.
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Frank MG, Levy ES, Bonnici GN, Maier SF, Baratta MV. Active coping mitigates the effects of stress on glucocorticoid levels in the prefrontal cortex. Brain Behav Immun. 2025 Nov; 130:106096.
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Thorne AJ, Gao A, Necker-Brown A, Bansal A, Kalyanaraman K, Chandramohan P, Sasse SK, Gerber AN, Mostafa MM, Newton R. Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid. Mol Pharmacol. 2025 Oct; 107(10):100073.
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Bauernfried S, Komar T, Sterle K, Tanzer MC, Horswill AR, Mann M, Hornung V. Inflammasome-independent IL-1ß activation via staphopain A protease of Staphylococcus aureus. J Biol Chem. 2025 10; 301(10):110574.
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Lippincott MJ, Tomkinson J, Bunten D, Mohammadi M, Kastl J, Knop J, Schwandner R, Huang J, Ongo G, Robichaud N, Dagher M, Mansilla-Soto A, Saravia-Estrada C, Tsuboi M, Basualto-Alarcón C, Way GP. A morphology and secretome map of pyroptosis. Mol Biol Cell. 2025 Jun 01; 36(6):ar63.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fernández-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 04; 640(8058):524-533.
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Amrute JM, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, Bredemeyer A, Jung IH, Kadyrov FF, Heo GS, Venkatesan R, Shi SY, Parvathaneni A, Koenig AL, Kuppe C, Baker C, Luehmann H, Jones C, Kopecky B, Zeng X, Bleckwehl T, Ma P, Lee P, Terada Y, Fu A, Furtado M, Kreisel D, Kovacs A, Stitziel NO, Jackson S, Li CM, Liu Y, Rosenthal NA, Kramann R, Ason B, Lavine KJ. Targeting immune-fibroblast cell communication in heart failure. Nature. 2024 11; 635(8038):423-433.
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