 Cyclic AMP
"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
| Descriptor ID |
D000242
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| MeSH Number(s) |
D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
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| Concept/Terms |
Cyclic AMP- Cyclic AMP
- AMP, Cyclic
- Adenosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Adenosine
- Adenosine Cyclic Monophosphate
- Cyclic Monophosphate, Adenosine
- Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3,5 Monophosphate
- Adenosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3',5' Monophosphate
- Cyclic 3',5'-Monophosphate, Adenosine
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Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".
This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 9 | 10 | | 1996 | 6 | 8 | 14 | | 1997 | 5 | 5 | 10 | | 1998 | 2 | 4 | 6 | | 1999 | 3 | 6 | 9 | | 2000 | 5 | 2 | 7 | | 2001 | 2 | 2 | 4 | | 2002 | 2 | 4 | 6 | | 2003 | 2 | 3 | 5 | | 2004 | 3 | 9 | 12 | | 2005 | 2 | 3 | 5 | | 2006 | 4 | 4 | 8 | | 2007 | 1 | 6 | 7 | | 2008 | 1 | 5 | 6 | | 2009 | 1 | 1 | 2 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 5 | 6 | | 2012 | 2 | 5 | 7 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 3 | 4 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 2 | 4 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 2 | 1 | 3 | | 2024 | 1 | 1 | 2 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cyclic AMP" by people in Profiles.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fern?ndez-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 Apr; 640(8058):524-533.
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Nick HJ, Christeson SE, Bratcher PE. VX-770, Cact-A1, and Increased Intracellular cAMP Have Distinct Acute Impacts upon CFTR Activity. Int J Mol Sci. 2025 Jan 08; 26(2).
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Yadav RS, Kushawaha B, Dhariya R, Swain DK, Yadav B, Anand M, Kumari P, Rai PK, Singh D, Yadav S, Garg SK. Lead and calcium crosstalk tempted acrosome damage and hyperpolarization of spermatozoa: signaling and ultra-structural evidences. Biol Res. 2024 Jul 05; 57(1):44.
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Peters CH, Singh RK, Langley AA, Nichols WG, Ferris HR, Jeffrey DA, Proenza C, Bankston JR. LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction. Elife. 2024 Apr 23; 12.
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Keller DM, Perez IG. Dual regulation of miR-375 and CREM genes in pancreatic beta cells. Islets. 2022 12 31; 14(1):139-148.
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Piguel NH, Yoon S, Gao R, Horan KE, Garza JC, Petryshen TL, Smith KR, Penzes P. Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3ß and cyclic AMP signaling pathways. Neuropsychopharmacology. 2023 06; 48(7):1000-1010.
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Mecca AA, Caprara GA, Peng AW. cAMP and voltage modulate rat auditory mechanotransduction by decreasing the stiffness of gating springs. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2107567119.
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Moghbeli K, Valenzi E, Naramore R, Sembrat JC, Chen K, Rojas MM, Wenzel SE, Lafyatis R, Modena B, Weathington NM. ?-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome. Am J Physiol Lung Cell Mol Physiol. 2021 11 01; 321(5):L837-L843.
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Yang B, Gelfanov VM, Perez-Tilve D, DuBois B, Rohlfs R, Levy J, Douros JD, Finan B, Mayer JP, DiMarchi RD. Optimization of Truncated Glucagon Peptides to Achieve Selective, High Potency, Full Antagonists. J Med Chem. 2021 04 22; 64(8):4697-4708.
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Peters CH, Myers ME, Juchno J, Haimbaugh C, Bichraoui H, Du Y, Bankston JR, Walker LA, Proenza C. Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):18079-18090.
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