 Small Molecule Libraries
"Small Molecule Libraries" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large collections of small molecules (molecular weight about 600 or less), of similar or diverse nature which are used for high-throughput screening analysis of the gene function, protein interaction, cellular processing, biochemical pathways, or other chemical interactions.
| Descriptor ID |
D054852
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| MeSH Number(s) |
D27.720.470.765
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| Concept/Terms |
Small Molecule Libraries- Small Molecule Libraries
- Libraries, Small Molecule
- Molecule Libraries, Small
- Molecular Libraries, Small
- Libraries, Small Molecular
- Small Molecular Libraries
- Chemical Libraries
- Libraries, Chemical
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Below are MeSH descriptors whose meaning is more general than "Small Molecule Libraries".
Below are MeSH descriptors whose meaning is more specific than "Small Molecule Libraries".
This graph shows the total number of publications written about "Small Molecule Libraries" by people in this website by year, and whether "Small Molecule Libraries" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 2 | 3 | | 2012 | 2 | 3 | 5 | | 2013 | 2 | 2 | 4 | | 2014 | 0 | 3 | 3 | | 2015 | 1 | 3 | 4 | | 2016 | 2 | 5 | 7 | | 2017 | 5 | 1 | 6 | | 2018 | 3 | 1 | 4 | | 2019 | 6 | 1 | 7 | | 2020 | 2 | 5 | 7 | | 2021 | 6 | 0 | 6 |
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Below are the most recent publications written about "Small Molecule Libraries" by people in Profiles.
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Ma XR, Xu L, Xu S, Klein BJ, Wang H, Das S, Li K, Yang KS, Sohail S, Chapman A, Kutateladze TG, Shi X, Liu WR, Wen H. Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain. J Med Chem. 2021 08 12; 64(15):10997-11013.
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Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease. Biochem J. 2021 07 16; 478(13):2465-2479.
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Canal B, McClure AW, Curran JF, Wu M, Ulferts R, Weissmann F, Zeng J, Bertolin AP, Milligan JC, Basu S, Drury LS, Deegan TD, Fujisawa R, Roberts EL, Basier C, Labib K, Beale R, Howell M, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. Biochem J. 2021 07 16; 478(13):2445-2464.
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Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. Biochem J. 2021 07 16; 478(13):2481-2497.
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Singh RK, Kumar S, Tomar MS, Verma PK, Kumar A, Kumar S, Kumar N, Singh JP, Acharya A. Putative role of natural products as Protein Kinase C modulator in different disease conditions. Daru. 2021 Dec; 29(2):397-414.
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Patel SB, Nemkov T, Stefanoni D, Benavides GA, Bassal MA, Crown BL, Matkins VR, Camacho V, Kuznetsova V, Hoang AT, Tenen DE, Wolock SL, Park J, Ying L, Yue Z, Chen JY, Yang H, Tenen DG, Ferrell PB, Lu R, Darley-Usmar V, D'Alessandro A, Bhatia R, Welner RS. Metabolic alterations mediated by STAT3 promotes drug persistence in CML. Leukemia. 2021 12; 35(12):3371-3382.
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Mainland JD, Barlow LA, Munger SD, Millar SE, Vergara MN, Jiang P, Schwob JE, Goldstein BJ, Boye SE, Martens JR, Leopold DA, Bartoshuk LM, Doty RL, Hummel T, Pinto JM, Trimmer C, Kelly C, Pribitkin EA, Reed DR. Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities. Chem Senses. 2020 10 09; 45(7):493-502.
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Zaugg J, Huang X, Ziegler F, Rubin M, Graff J, M?ller J, Moser-H?ssig R, Powell T, Gertsch J, Altmann KH, Albrecht C. Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport. J Cell Mol Med. 2020 11; 24(21):12681-12693.
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Zivanovic S, Colizzi F, Moreno D, Hospital A, Soliva R, Orozco M. Exploring the Conformational Landscape of Bioactive Small Molecules. J Chem Theory Comput. 2020 Oct 13; 16(10):6575-6585.
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Braselmann E, Rathbun C, Richards EM, Palmer AE. Illuminating RNA Biology: Tools for Imaging RNA in Live Mammalian Cells. Cell Chem Biol. 2020 08 20; 27(8):891-903.
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