Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Descriptor ID |
D016207
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MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 9 | 6 | 15 | 1995 | 7 | 6 | 13 | 1996 | 6 | 11 | 17 | 1997 | 6 | 10 | 16 | 1998 | 13 | 11 | 24 | 1999 | 11 | 12 | 23 | 2000 | 10 | 11 | 21 | 2001 | 6 | 11 | 17 | 2002 | 15 | 9 | 24 | 2003 | 15 | 20 | 35 | 2004 | 16 | 30 | 46 | 2005 | 26 | 30 | 56 | 2006 | 16 | 37 | 53 | 2007 | 17 | 34 | 51 | 2008 | 25 | 40 | 65 | 2009 | 24 | 38 | 62 | 2010 | 21 | 34 | 55 | 2011 | 13 | 41 | 54 | 2012 | 15 | 39 | 54 | 2013 | 12 | 37 | 49 | 2014 | 9 | 51 | 60 | 2015 | 17 | 27 | 44 | 2016 | 19 | 35 | 54 | 2017 | 17 | 43 | 60 | 2018 | 20 | 51 | 71 | 2019 | 13 | 39 | 52 | 2020 | 12 | 25 | 37 | 2021 | 20 | 36 | 56 | 2022 | 3 | 29 | 32 | 2023 | 3 | 35 | 38 | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death. Mol Cancer Res. 2024 Feb 01; 22(2):209-220.
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Haystead T, Lee E, Cho K, Gullickson G, Hughes P, Krafsur G, Freeze R, Scarneo S. Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein. Sci Rep. 2023 12 18; 13(1):22873.
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Okurut S, Boulware DR, Okafor E, Rhein J, Kajumbula H, Bagaya BS, Bwanga F, Olobo JO, Manabe YC, Meya DB, Janoff EN. Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis. Front Immunol. 2023; 14:1275443.
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Roy RM, Allawzi A, Burns N, Sul C, Rubio V, Graham J, Stenmark K, Nozik ES, Tuder RM, Vohwinkel CU. Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury. FASEB J. 2023 12; 37(12):e23316.
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Scott TE, Lewis CV, Zhu M, Wang C, Samuel CS, Drummond GR, Kemp-Harper BK. IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages. Sci Rep. 2023 11 10; 13(1):19589.
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Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF, Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. 2023 Nov; 623(7987):616-624.
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Jeyabal P, Bhagat A, Wang F, Roth M, Livingston JA, Gilchrist SC, Banchs J, Hildebrandt MAT, Chandra J, Deswal A, Koutroumpakis E, Wang J, Daw NC, Honey TA, Kleinerman ES. Circulating microRNAs and Cytokines as Prognostic Biomarkers for Doxorubicin-Induced Cardiac Injury and for Evaluating the Effectiveness of an Exercise Intervention. Clin Cancer Res. 2023 11 01; 29(21):4430-4440.
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Westrich JA, McNulty EE, Carpenter M, Burton M, Reed K, Nalls A, Sandoval A, Mayo C, Mathiason CK. Monitoring longitudinal immunological responses to bluetongue virus 17 in experimentally infected sheep. Virus Res. 2023 12; 338:199246.
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Gao J, Li Y, Guan X, Mohammed Z, Gomez G, Hui Y, Zhao D, Oskeritzian CA, Huang H. IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells. BMC Genomics. 2023 Oct 06; 24(1):592.
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Cantoni E, Merelli I, Stefanoni D, Tomelleri A, Campochiaro C, Giordano V, Panigada M, Baldissera EM, Merlo Pich L, Natoli V, Ziogas A, Dom?nguez-Andr?s J, De Luca G, Mazza D, Zambrano S, Gnani D, Ferrarini M, Ferrero E, Agresti A, Vergani B, Leone BE, Cenci S, Ravelli A, Matucci-Cerinic M, D'Alessandro A, Joosten LAB, Dagna L, Netea MG, Molteni R, Cavalli G. Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production. Rheumatology (Oxford). 2023 10 03; 62(10):3469-3479.
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