 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 7 | 6 | 13 | | 1996 | 6 | 12 | 18 | | 1997 | 8 | 10 | 18 | | 1998 | 14 | 10 | 24 | | 1999 | 9 | 11 | 20 | | 2000 | 9 | 12 | 21 | | 2001 | 8 | 13 | 21 | | 2002 | 15 | 18 | 33 | | 2003 | 15 | 19 | 34 | | 2004 | 15 | 32 | 47 | | 2005 | 24 | 30 | 54 | | 2006 | 17 | 35 | 52 | | 2007 | 15 | 29 | 44 | | 2008 | 24 | 40 | 64 | | 2009 | 24 | 42 | 66 | | 2010 | 19 | 33 | 52 | | 2011 | 15 | 44 | 59 | | 2012 | 15 | 40 | 55 | | 2013 | 14 | 39 | 53 | | 2014 | 13 | 52 | 65 | | 2015 | 21 | 34 | 55 | | 2016 | 18 | 33 | 51 | | 2017 | 19 | 47 | 66 | | 2018 | 22 | 56 | 78 | | 2019 | 16 | 46 | 62 | | 2020 | 17 | 38 | 55 | | 2021 | 22 | 42 | 64 | | 2022 | 4 | 41 | 45 | | 2023 | 6 | 45 | 51 | | 2024 | 7 | 25 | 32 | | 2025 | 8 | 21 | 29 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Yaeger MJ, Ngatikaura T, Zecchino N, Lovins HB, Schott E, Cochran SJ, Hutton G, Ray JL, Saunders B, Leuenberger LA, Kilburg-Basnyat B, Virk R, Van Duinen R, Mo X, Armstrong M, McFadden MI, Fenton JI, Reisdorph N, Forero A, Ballinger MN, Tighe RM, Shaikh SR, Gowdy KM. Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation. Am J Respir Cell Mol Biol. 2025 Nov; 73(5):741-754.
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Virk R, Behee M, Al-Shaer A, Wagner M, Armstrong M, Reisdorph N, Bathon B, Beatty N, Davis T, Yaeger MJ, Gray RS, Bridges MD, Gowdy KM, Shaikh SR. Genetic deletion of Alx/Fpr2 differentially regulates pulmonary inflammation in the absence and presence of acute lung injury. Immunohorizons. 2025 Sep 17; 9(10).
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Thorne AJ, Gao A, Necker-Brown A, Bansal A, Kalyanaraman K, Chandramohan P, Sasse SK, Gerber AN, Mostafa MM, Newton R. Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid. Mol Pharmacol. 2025 Oct; 107(10):100073.
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Rice MR, Matta B, Wang L, Luo Q, De Guzman J, Srinivasan D, Ludwig KR, Indukuri S, Brune L, Tan SL, Barnes BJ. TLR-induced STK25 activation promotes IRF5-mediated inflammation. Life Sci Alliance. 2025 Sep; 8(9).
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McElwee ER, Hatchell D, Alshareef M, Mallah K, Hall H, Robinson H, Eskandari R, Chang E, Sullivan S, Tomlinson S. Complement Modulation Mitigates Inflammation-Mediated Preterm Birth and Fetal Neural Inflammation. Cells. 2025 Jul 08; 14(14).
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Karafin MS, Grier AL, Fasano RM, Ilich A, Wichlan D, Chang A, James SM, Butler HE, Kolupaev O, Caughey MC, Stephenson DJ, Reisz JA, Key NS, Field JJ, Little JA, Spitalnik SL, D'Alessandro A. Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions. J Clin Invest. 2025 Sep 02; 135(17).
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Verma M, Can UI, Reinhardt RL. ILC2 Diversity, Location, and Function in Pulmonary Disease. Immunol Rev. 2025 Jul; 332(1):e70036.
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Klawitter J, Clauw AD, Seifert JA, Klawitter J, Tompson B, Sempio C, Ingram SL, Christians U, Moreland LW. Endocannabinoid Tone and Oxylipins in Rheumatoid Arthritis and Osteoarthritis-A Novel Target for the Treatment of Pain and Inflammation? Int J Mol Sci. 2025 Jun 14; 26(12).
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Basu A, Pommerolle L, Arif M, Meliton AY, Udofia I, Wu D, Mutlu GM, Gochuico BR, Summer R, Adegunsoye A, Burnham EL, Cinar R. Elevated blood anandamide levels in acute COVID-19 pneumonia with respiratory failure. Am J Med Sci. 2025 Sep; 370(3):271-277.
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Niehaus C, Geanon D, Lietzau A, Jankovic M, Maucourant C, Maasoumy B, Sparrelid E, Wedemeyer H, Kahlhöfer J, Falk CS, Andrade IM, Ponzetta A, Björkström NK, Kraft ARM, Cornberg M, Strunz B. Origin of Hypofunctional CD103+ NK Cells in Cirrhosis-Associated Ascites. Eur J Immunol. 2025 Jun; 55(6):e51311.
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