 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 12 | 18 | | 1997 | 8 | 10 | 18 | | 1998 | 14 | 10 | 24 | | 1999 | 9 | 11 | 20 | | 2000 | 9 | 11 | 20 | | 2001 | 8 | 13 | 21 | | 2002 | 14 | 17 | 31 | | 2003 | 15 | 19 | 34 | | 2004 | 14 | 32 | 46 | | 2005 | 24 | 29 | 53 | | 2006 | 16 | 34 | 50 | | 2007 | 15 | 28 | 43 | | 2008 | 24 | 40 | 64 | | 2009 | 24 | 42 | 66 | | 2010 | 19 | 33 | 52 | | 2011 | 14 | 44 | 58 | | 2012 | 14 | 40 | 54 | | 2013 | 15 | 38 | 53 | | 2014 | 15 | 51 | 66 | | 2015 | 21 | 33 | 54 | | 2016 | 18 | 34 | 52 | | 2017 | 20 | 46 | 66 | | 2018 | 21 | 56 | 77 | | 2019 | 16 | 48 | 64 | | 2020 | 17 | 38 | 55 | | 2021 | 21 | 44 | 65 | | 2022 | 4 | 39 | 43 | | 2023 | 6 | 44 | 50 | | 2024 | 8 | 25 | 33 | | 2025 | 10 | 26 | 36 | | 2026 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Huang C, Babu VS, Bammidi S, Arnold JN, Ebeling M, Widmer G, Strassburger P, Lazendic M, Grüner S, Koester J, Dutta P, Hose S, Singh S, Gautam P, Lad EM, Westenskow PD, Kutsyr O, Csaky KG, Ghosh S, Sripathi SR, Proia AD, Flores-Bellver M, Sinha D, Feenstra D. STING activation induces polarized cytokine secretion of IFN-ß and IL-17A promoting photoreceptor death and choroidal disruption in age-related macular degeneration. Cell Death Dis. 2026 Feb 27; 17(1).
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Sirohi K, Sripada A, Verma M, Varma R, Liu S, Yadav S, Sahu A, Manka L, Guntur VP, Gorska MM, Alam R. CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells. Sci Adv. 2026 Feb 13; 12(7):eadj4926.
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Glaser N, Chaffin Z, Tancredi D, Rewers A, Rewers M, Gilles S, Ander B, Ghetti S. Inflammatory profile associated with hyperglycemia in children with type 1 diabetes. J Diabetes Complications. 2026 Mar; 40(3):109275.
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Necker-Brown A, Mostafa MM, Georgescu A, Thorne AJ, Chandramohan P, Kooi C, Kalyanaraman K, Gao A, Bansal A, Sasse SK, Gerber AN, Leigh R, Newton R. Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-?B. PLoS One. 2025; 20(12):e0329244.
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O'Leary S, Prasai A, Robledo A, Thang C, Wang Y, Deshpande RR, Russell WK, Murton AJ, Wolf SE, El Ayadi A. Altered lipid profiles in the prefrontal cortex are associated with neuroinflammation after severe burn injury. Front Immunol. 2025; 16:1709256.
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Decker Ramirez EB, Schank JR. Sex differences in inflammatory mechanisms related to alcohol use disorder and depression. Brain Behav Immun. 2026 Jan; 131:106172.
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Kaneko S, Mizuta M, Hatano M, Shimbo A, Irabu H, Yatabe R, Akamine K, Sugita Y, Hashimoto K, Yamasaki Y, Nakagishi Y, Mori M, Takagi M, Shimizu M. Distinct cytokine signature in juvenile dermatomyositis: linking myositis-specific antibodies and clinical manifestations. Cytokine. 2026 Jan; 197:157070.
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Jenkins BJ, Jenkins YR, Ponce-Garcia FM, Moscrop C, Perry IA, Hitchings MD, Uribe AH, Bernuzzi F, Eastham S, Cronin JG, Berisha A, Howell A, Davies J, Blagih J, Williams M, Marsden M, Veale DJ, Davies LC, Niphakis M, Finlay DK, Sinclair LV, Cravatt BF, Hogan AE, Nathan JA, Humphreys IR, Fearon U, Sumpton D, Vande Voorde J, Vale GDD, McDonald JG, Jones GW, Pearson JA, Vincent EE, Jones N. Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function. Nat Commun. 2025 Nov 03; 16(1):9484.
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Yaeger MJ, Ngatikaura T, Zecchino N, Lovins HB, Schott E, Cochran SJ, Hutton G, Ray JL, Saunders B, Leuenberger LA, Kilburg-Basnyat B, Virk R, Van Duinen R, Mo X, Armstrong M, McFadden MI, Fenton JI, Reisdorph N, Forero A, Ballinger MN, Tighe RM, Shaikh SR, Gowdy KM. Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation. Am J Respir Cell Mol Biol. 2025 Nov; 73(5):741-754.
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Saunders EF, Schultz KR, Lowe I, Anderson AL, Bikkumalla VS, Soto D, Tran NY, Baumel-Alterzon S, Knight JD, Shearn CT. Rapid protein carbonylation and decreased insulin secretion induced by inflammatory oxidative stress compounds. Free Radic Biol Med. 2026 Jan; 242:320-332.
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