 Gene Silencing
"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
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| MeSH Number(s) |
G05.308.203.374
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| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
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Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 1 | 5 | 6 | | 2006 | 2 | 7 | 9 | | 2007 | 2 | 5 | 7 | | 2008 | 1 | 7 | 8 | | 2009 | 2 | 3 | 5 | | 2010 | 2 | 2 | 4 | | 2011 | 4 | 9 | 13 | | 2012 | 1 | 4 | 5 | | 2013 | 6 | 3 | 9 | | 2014 | 2 | 3 | 5 | | 2015 | 1 | 8 | 9 | | 2016 | 3 | 10 | 13 | | 2017 | 2 | 5 | 7 | | 2018 | 1 | 5 | 6 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 5 | 6 | | 2021 | 0 | 3 | 3 | | 2022 | 1 | 1 | 2 | | 2023 | 0 | 2 | 2 | | 2025 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Gaurav N, O'Hara R, Hyder U, Qin W, Her C, Romero H, Kumar A, Marcaida MJ, Singh RK, Hovius R, Selvam K, Liu J, Martire S, Yao Y, Challa A, Dal Peraro M, Fierz B, Kono H, Cardoso MC, Debelouchina GT, Leonhardt H, D'Orso I, Banaszynski LA, Kutateladze TG. The HP1 box of KAP1 organizes HP1a for silencing of endogenous retroviral elements in embryonic stem cells. Nat Commun. 2025 May 31; 16(1):5066.
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Pratap A, Monge KM, Qualman AC, Kovacs EJ, Idrovo JP. Burn-induced mitochondrial dysfunction in hepatocytes: The role of methylation-controlled J protein silencing. J Trauma Acute Care Surg. 2025 Feb 01; 98(2):204-211.
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Rosas R, Aguilar RR, Arslanovic N, Seck A, Smith DJ, Tyler JK, Churchill MEA. A novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function. Elife. 2023 07 11; 12.
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Tatavosian R, Donovan MG, Galbraith MD, Duc HN, Szwarc MM, Joshi MU, Frieman A, Bilousova G, Cao Y, Smith KP, Song K, Rachubinski AL, Andrysik Z, Espinosa JM. Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation. Cell Death Differ. 2023 04; 30(4):952-965.
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Cialek CA, Galindo G, Morisaki T, Zhao N, Montgomery TA, Stasevich TJ. Imaging translational control by Argonaute with single-molecule resolution in live cells. Nat Commun. 2022 06 10; 13(1):3345.
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Kraft K, Yost KE, Murphy SE, Magg A, Long Y, Corces MR, Granja JM, Wittler L, Mundlos S, Cech TR, Boettiger AN, Chang HY. Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation. Proc Natl Acad Sci U S A. 2022 05 31; 119(22):e2201883119.
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Shoda T, Wen T, Caldwell JM, Ben-Baruch Morgenstern N, Osswald GA, Rochman M, Mack LE, Felton JM, Abonia JP, Arva NC, Atkins D, Bonis PA, Capocelli KE, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Putnam PE, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022 02; 162(2):439-453.
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Nandi P, Jang CE, Biggar K, Halari CD, Jansson T, Gupta MB. Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells. Biomolecules. 2021 09 18; 11(9).
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Wright CJ, McKenna S, De Dios R, Boehmer BH, Nguyen L, Ghosh S, Sandoval J, Rozance PJ. Lower threshold to NF?B activity sensitizes murine ?-cells to streptozotocin. J Endocrinol. 2021 05 06; 249(3):163-175.
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Wu SK, Roberts JT, Balas MM, Johnson AM. RNA matchmaking in chromatin regulation. Biochem Soc Trans. 2020 12 18; 48(6):2467-2481.
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