 Cell Differentiation
"Cell Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
| Descriptor ID |
D002454
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| MeSH Number(s) |
G04.152
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| Concept/Terms |
Cell Differentiation- Cell Differentiation
- Differentiation, Cell
- Cell Differentiations
- Differentiations, Cell
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Below are MeSH descriptors whose meaning is more general than "Cell Differentiation".
Below are MeSH descriptors whose meaning is more specific than "Cell Differentiation".
This graph shows the total number of publications written about "Cell Differentiation" by people in this website by year, and whether "Cell Differentiation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 16 | 16 | | 1997 | 0 | 19 | 19 | | 1998 | 1 | 24 | 25 | | 1999 | 1 | 16 | 17 | | 2000 | 3 | 20 | 23 | | 2001 | 4 | 28 | 32 | | 2002 | 8 | 39 | 47 | | 2003 | 5 | 29 | 34 | | 2004 | 15 | 37 | 52 | | 2005 | 9 | 37 | 46 | | 2006 | 14 | 30 | 44 | | 2007 | 24 | 34 | 58 | | 2008 | 16 | 37 | 53 | | 2009 | 16 | 43 | 59 | | 2010 | 20 | 44 | 64 | | 2011 | 15 | 38 | 53 | | 2012 | 21 | 45 | 66 | | 2013 | 21 | 45 | 66 | | 2014 | 32 | 43 | 75 | | 2015 | 30 | 48 | 78 | | 2016 | 22 | 28 | 50 | | 2017 | 16 | 37 | 53 | | 2018 | 19 | 56 | 75 | | 2019 | 17 | 37 | 54 | | 2020 | 15 | 52 | 67 | | 2021 | 12 | 51 | 63 | | 2022 | 3 | 30 | 33 | | 2023 | 1 | 37 | 38 | | 2024 | 9 | 23 | 32 | | 2025 | 9 | 27 | 36 | | 2026 | 4 | 18 | 22 |
To return to the timeline, click here.
Below are the most recent publications written about "Cell Differentiation" by people in Profiles.
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Ghebrechristos YE, Evensen NA, Cathelin RS, Lee S, Clark F, Saiz N, Clarke S, Witkowski MT, Lin Z, Narang S, Zhou H, Raetz E, Teachey DT, Lionnet T, Tsirigos A, Carroll WL, Aifantis I. 3D Chromosome Remodeling in B-cell Development and Acute Lymphoblastic Leukemia. Blood Cancer Discov. 2026 Jul 01; 7(4):586-605.
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Balolia A, Arena KA, Shahood A, Russom H, Tran LN, Winkler CC, O'Rourke R, Vue TY, Sagerström CG, Appel BH, Franco SJ. Ascl1 promotes OPC specification across species and central nervous system regions and its gliogenic function is regulated by phosphorylation. Dev Biol. 2026 Aug; 536:184-201.
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Krug B, Hu B, Chen H, Negrón-Lomas C, Chen X, El Mouatani A, Gretarsson KH, Ptack A, Deshmukh S, Kabir N, Jawhar W, Andrade AF, Jabbour E, Harutyunyan AS, Wang X, Taylor R, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Yang J, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C. H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs. Nat Genet. 2026 Jun; 58(6):1368-1382.
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Zöller M, Mastalerz M, Dick E, Merl-Pham J, Hennen E, Prakki SRS, Chakraborty A, Nakayama M, Klotz M, Marchi H, LeGleut R, De Sadeleer LJ, Wuyts WA, Vanaudenaerde BM, Jeridi A, Prasse A, Jäger B, Santofimia-Castaño P, Stoleriu MG, Hilgendorff A, Hauck SM, Yildirim AÖ, Schiller H, Staab-Weijnitz CA. Nuclear protein 1 is a cell death regulator in primary human airway epithelial cells and reduced in idiopathic pulmonary fibrosis. Sci Rep. 2026 May 11; 16(1).
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Gracey EG, Kandel SE, Lampe JN. A CYP3A7 metabolically competent human induced pluripotent stem cell-derived hepatocyte-like cell (hHLC3A7) model for drug safety assessment in the newborn. Drug Metab Dispos. 2026 Jun; 54(6):100314.
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Zaganelli S, Meehl JB, Abrisch RG, Voeltz GK. Nuclear envelope budding enables export of large transcripts in muscle cells. Cell. 2026 May 28; 189(11):3398-3412.e13.
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Steffes LC, Chiles KA, Masud SR, Rahman A, Dawson M, Galambos C, Kumar ME, Arora R. Excessive postnatal smooth muscle differentiation in a lung-specific model of TBX4-related pulmonary hypertension. JCI Insight. 2026 Jun 08; 11(11).
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Piarowski CM, Scott JK, Wilson CE, Lara HI, Salcedo E, Han AS, Lam ET, Dempsey PJ, von Moltke J, Barlow LA. Tyrosine kinase inhibitors affect sweet taste and dysregulate fate selection of specific taste bud cell subtypes via KIT inhibition. Development. 2026 Apr 15; 153(8).
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Ornelas A, Countess JA, Kim JY, Cohen RH, Gomez BD, Roer RL, Minhajuddin F, Yenugudhati Vijaya Sai K, Zhou L, Dunn JLM, Chandler C, Reigan P, Cartwright IM, Hall CHT, Bhagavatula G, Onyiah JC, Dowdell AS, Colgan SP. Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa. Proc Natl Acad Sci U S A. 2026 Apr 14; 123(15):e2527863123.
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Jewett CE, Holland AJ, Pearson CG. The DNA damage response pathway is required for multiciliated cell differentiation. Curr Biol. 2026 Apr 20; 36(8):2156-2166.e3.
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