 NF-E2-Related Factor 2
"NF-E2-Related Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.
| Descriptor ID |
D051267
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| MeSH Number(s) |
D12.776.260.108.737 D12.776.930.127.737
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| Concept/Terms |
NF-E2-Related Factor 2- NF-E2-Related Factor 2
- NF E2 Related Factor 2
- Nuclear Factor E2-Related Factor 2
- Nuclear Factor E2 Related Factor 2
- Nfe2l2 Protein
- Nuclear Factor (Erythroid-Derived 2)-Like 2 Protein
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Below are MeSH descriptors whose meaning is more general than "NF-E2-Related Factor 2".
Below are MeSH descriptors whose meaning is more specific than "NF-E2-Related Factor 2".
This graph shows the total number of publications written about "NF-E2-Related Factor 2" by people in this website by year, and whether "NF-E2-Related Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 4 | 0 | 4 | | 2009 | 1 | 2 | 3 | | 2011 | 3 | 1 | 4 | | 2012 | 3 | 0 | 3 | | 2013 | 5 | 1 | 6 | | 2014 | 1 | 3 | 4 | | 2015 | 1 | 1 | 2 | | 2016 | 3 | 0 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 1 | 3 | | 2022 | 2 | 5 | 7 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "NF-E2-Related Factor 2" by people in Profiles.
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Profeta V, McIntyre K, Wells M, Park C, Lynch DR. Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia. Expert Opin Investig Drugs. 2023 Jan; 32(1):5-16.
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Iams WT, Balbach ML, Phillips S, Sacher A, Bestvina C, Velcheti V, Wang X, Marmarelis ME, Sethakorn N, Leal T, Sackstein PE, Kim C, Robinson MA, Mehta K, Hsu R, Nieva J, Patil T, Camidge DR. A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer. Clin Lung Cancer. 2023 05; 24(3):228-234.
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Ide S, Ide K, Abe K, Kobayashi Y, Kitai H, McKey J, Strausser SA, O'Brien LL, Tata A, Tata PR, Souma T. Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair. Cell Rep. 2022 11 08; 41(6):111610.
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Sato Y, Saito S, Nakayama M, Sugita S, Kudo A, Keino H. Genetic Ablation of Nrf2 Exacerbates Neuroinflammation in Ocular Autoimmunity. Int J Mol Sci. 2022 Oct 03; 23(19).
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Musci RV, Andrie KM, Walsh MA, Valenti ZJ, Linden MA, Afzali MF, Bork S, Campbell M, Johnson T, Kail TE, Martinez R, Nguyen T, Sanford J, Wist S, Murrell MD, McCord JM, Hybertson BM, Zhang Q, Javors MA, Santangelo KS, Hamilton KL. Phytochemical compound PB125 attenuates skeletal muscle mitochondrial dysfunction and impaired proteostasis in a model of musculoskeletal decline. J Physiol. 2023 06; 601(11):2189-2216.
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Williams MM, Richer JK. Revealing Molecular Mechanisms Supporting Trophoblast-Mediated Maternal Immune Tolerance. Endocrinology. 2022 08 01; 163(8).
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Keita M, McIntyre K, Rodden LN, Schadt K, Lynch DR. Friedreich ataxia: clinical features and new developments. Neurodegener Dis Manag. 2022 10; 12(5):267-283.
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Ishitsuka Y, Roop DR. Loricrin at the Boundary between Inside and Outside. Biomolecules. 2022 05 06; 12(5).
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Green-Fulgham SM, Harland ME, Ball JB, Li J, Lacagnina MJ, D'Angelo H, Dreher RA, Willcox KF, Lorca SA, Kwilasz AJ, Maier SF, Watkins LR, Grace PM. Preconditioning by voluntary wheel running attenuates later neuropathic pain via nuclear factor E2-related factor 2 antioxidant signaling in rats. Pain. 2022 10 01; 163(10):1939-1951.
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Shiels PG, Painer J, Natterson-Horowitz B, Johnson RJ, Miranda JJ, Stenvinkel P. Manipulating the exposome to enable better ageing. Biochem J. 2021 07 30; 478(14):2889-2898.
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