 Transfection
"Transfection" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
| Descriptor ID |
D014162
|
| MeSH Number(s) |
E05.393.350.810 G05.728.860
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Transfection".
Below are MeSH descriptors whose meaning is more specific than "Transfection".
This graph shows the total number of publications written about "Transfection" by people in this website by year, and whether "Transfection" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 17 | 17 | | 1997 | 1 | 18 | 19 | | 1998 | 2 | 19 | 21 | | 1999 | 1 | 23 | 24 | | 2000 | 0 | 44 | 44 | | 2001 | 3 | 41 | 44 | | 2002 | 1 | 38 | 39 | | 2003 | 6 | 44 | 50 | | 2004 | 3 | 31 | 34 | | 2005 | 1 | 35 | 36 | | 2006 | 0 | 42 | 42 | | 2007 | 0 | 24 | 24 | | 2008 | 4 | 26 | 30 | | 2009 | 2 | 35 | 37 | | 2010 | 1 | 25 | 26 | | 2011 | 2 | 19 | 21 | | 2012 | 1 | 31 | 32 | | 2013 | 4 | 15 | 19 | | 2014 | 4 | 14 | 18 | | 2015 | 3 | 15 | 18 | | 2016 | 1 | 16 | 17 | | 2017 | 1 | 14 | 15 | | 2018 | 2 | 7 | 9 | | 2019 | 0 | 9 | 9 | | 2020 | 0 | 5 | 5 | | 2021 | 0 | 5 | 5 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 1 | 5 | 6 | | 2025 | 0 | 4 | 4 | | 2026 | 1 | 3 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Transfection" by people in Profiles.
-
Akh L, Fajrial AK, Sohn S, Seelbinder B, Xu X, Tan W, Slansky JE, Neu CP, Ding X. Vector-free DNA transfection by nuclear envelope mechanoporation. Lab Chip. 2026 May 05; 26(9):2673-2683.
-
Kim D, Moon SJ, Han EL, Feng E, Murray AM, Wang J, Liu W, Kong G, June CH, Mitchell MJ. HITE: HIV Inspired Lipid Nanoparticle Platform for CAR T Cell Engineering. Nano Lett. 2026 May 06; 26(17):5668-5679.
-
Hamilton AG, Thatte AS, Xu J, Luo Z, Safford HC, Swingle KL, Muscat-Rivera J, Kegel M, Han X, Joseph RA, Murray AM, Geisler HC, Whitaker RC, Xue L, Spektor R, Melamed JR, Weissman D, Mitchell MJ. High-Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering. Adv Mater. 2026 Mar; 38(13):e14370.
-
Han EL, Kim D, Murray AM, Mrksich K, Hamilton AG, Tang S, Yoo S, Zhu AT, Tong ER, Palanki R, Hall ML, Bedingfield SK, Mitchell MJ. High-Throughput In Vivo Screening Identifies Structural Factors Driving mRNA Lipid Nanoparticle Delivery to the Brain. ACS Nano. 2026 Feb 03; 20(4):3807-3820.
-
Yoo S, Han EL, Murray AM, Kim D, Bang EK, Mitchell MJ. High-Throughput Formulation Using Fast mRNA Lipid Nanoparticle Assembly via Simple Thermomixing (HTF-FLASH). Nano Lett. 2025 10 08; 25(40):14695-14703.
-
Sekar RP, Lawson JL, McGrath C, Wheeler G, Moreau G, Johansen CG, Farnsworth NL, Kumar R. Tuning DLVO Interactions Alters Polymer-Mediated pDNA Delivery in a Cell Type-Dependent Manner. Langmuir. 2025 Jul 15; 41(27):17426-17438.
-
Shin JE, Won EJ, Xu J, Lee JC, Bang JK, Mitchell MJ, Cha-Molstad H. Transition Temperature-Guided Design of Lipid Nanoparticles for Effective mRNA Delivery. ACS Appl Mater Interfaces. 2025 May 14; 17(19):28012-28024.
-
Padilla MS, Mrksich K, Wang Y, Haley RM, Li JJ, Han EL, El-Mayta R, Kim EH, Dias S, Gong N, Teerdhala SV, Han X, Chowdhary V, Xue L, Siddiqui Z, Yamagata HM, Kim D, Yoon IC, Wilson JM, Radhakrishnan R, Mitchell MJ. Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering. Nat Commun. 2025 Jan 24; 16(1):996.
-
Han EL, Tang S, Kim D, Murray AM, Swingle KL, Hamilton AG, Mrksich K, Padilla MS, Palanki R, Li JJ, Mitchell MJ. Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain. Nano Lett. 2025 01 15; 25(2):800-810.
-
Nunes LGA, Rosario FJ, Urschitz J. In vivo placental gene modulation via sonoporation. Placenta. 2025 Jun 13; 166:109-116.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|