 Extracellular Matrix
"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
| Descriptor ID |
D005109
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| MeSH Number(s) |
A11.284.295.310
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| Concept/Terms |
Extracellular Matrix- Extracellular Matrix
- Matrix, Extracellular
- Extracellular Matrices
- Matrices, Extracellular
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Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".
This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1997 | 1 | 1 | 2 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 5 | 8 | | 2004 | 2 | 7 | 9 | | 2005 | 3 | 5 | 8 | | 2006 | 5 | 4 | 9 | | 2007 | 4 | 2 | 6 | | 2008 | 5 | 7 | 12 | | 2009 | 10 | 8 | 18 | | 2010 | 3 | 5 | 8 | | 2011 | 4 | 11 | 15 | | 2012 | 8 | 6 | 14 | | 2013 | 4 | 9 | 13 | | 2014 | 7 | 11 | 18 | | 2015 | 7 | 6 | 13 | | 2016 | 12 | 11 | 23 | | 2017 | 6 | 10 | 16 | | 2018 | 11 | 7 | 18 | | 2019 | 10 | 9 | 19 | | 2020 | 6 | 13 | 19 | | 2021 | 8 | 10 | 18 | | 2022 | 2 | 15 | 17 | | 2023 | 1 | 11 | 12 | | 2024 | 5 | 11 | 16 | | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.
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Lewis CV, Nguyen TN, Porfilio TE, Burciaga SD, Posey JN, Jordan M, Colon Hidalgo D, Stenmark KR, Mickael C, Sul C, Oberley-Deegan RE, Delaney C, Nozik ES. Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia. Am J Physiol Lung Cell Mol Physiol. 2025 Jun 01; 328(6):L885-L900.
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Gorashi RM, Baddour T, Chittle SJ, F?lix V?lez NE, Wenning MA, Anseth KS, Mestroni L, Pe?a B, Guo P, Aguado BA. Y chromosome-linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. Sci Adv. 2025 Mar 14; 11(11):eads5717.
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Di Caprio N, Hughes AJ, Burdick JA. Programmed shape transformations in cell-laden granular composites. Sci Adv. 2025 Jan 17; 11(3):eadq5011.
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Rutt LN, Orlicky DJ, McCullough RL. Investigating the role of Wnt3a and Wnt5a as critical factors of hepatic stellate cell activation in acute toxicant-induced liver injury. Cell Biol Toxicol. 2024 12 21; 41(1):5.
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Bast?as CS, Savard LM, Jacobson KR, Connell KA, Calve S, Ferguson VL, Luetkemeyer CM. Pregnancy and age differentially affect stiffness, injury susceptibility, and composition of murine uterosacral ligaments. J Mech Behav Biomed Mater. 2025 Mar; 163:106874.
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Ohnsorg ML, Hushka EA, Anseth KS. Photoresponsive Chemistries for User-Directed Hydrogel Network Modulation to Investigate Cell-Matrix Interactions. Acc Chem Res. 2025 01 07; 58(1):47-60.
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Williams J, Iheagwam FN, Maroney SP, Schmitt LR, Brown RD, Krafsur GM, Frid MG, McCabe MC, Gandjeva A, Williams KJ, Luyendyk JP, Saviola AJ, Tuder RM, Stenmark K, Hansen KC. A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation. Am J Physiol Cell Physiol. 2024 Dec 01; 327(6):C1666-C1680.
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Bourgeau M, Marshall CB, Schowinsky JT, Lindeque B, Clay MR. Synthetic Electrospun Fiber Matrix May Resemble Fungal Hyphae Over the Course of Tissue Regeneration: A Retrospective Review. Int J Surg Pathol. 2025 Apr; 33(2):389-393.
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Lewis CV, Garcia AM, Burciaga SD, Posey JN, Jordan M, Nguyen TN, Stenmark KR, Mickael C, Sul C, Delaney C, Nozik ES. Redistribution of SOD3 expression due to R213G polymorphism affects pulmonary interstitial macrophage reprogramming in response to hypoxia. Physiol Genomics. 2024 Nov 01; 56(11):776-790.
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O'Connell BC, Hubbard C, Zizlsperger N, Fitzgerald D, Kutok JL, Varner J, Ilaria R, Cobleigh MA, Juric D, Tkaczuk KHR, Elias A, Lee A, Dakhil S, Hamilton E, Soliman H, Peluso S. Eganelisib combined with immune checkpoint inhibitor therapy and chemotherapy in frontline metastatic triple-negative breast cancer triggers macrophage reprogramming, immune activation and extracellular matrix reorganization in the tumor microenvironment. J Immunother Cancer. 2024 Aug 30; 12(8).
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