 Extracellular Matrix
"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
| Descriptor ID |
D005109
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| MeSH Number(s) |
A11.284.295.310
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| Concept/Terms |
Extracellular Matrix- Extracellular Matrix
- Matrix, Extracellular
- Extracellular Matrices
- Matrices, Extracellular
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Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".
This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 3 | 1 | 4 | | 2000 | 1 | 2 | 3 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 5 | 8 | | 2004 | 2 | 7 | 9 | | 2005 | 3 | 6 | 9 | | 2006 | 5 | 5 | 10 | | 2007 | 3 | 2 | 5 | | 2008 | 5 | 7 | 12 | | 2009 | 10 | 8 | 18 | | 2010 | 3 | 5 | 8 | | 2011 | 4 | 11 | 15 | | 2012 | 8 | 6 | 14 | | 2013 | 4 | 9 | 13 | | 2014 | 8 | 11 | 19 | | 2015 | 8 | 6 | 14 | | 2016 | 13 | 11 | 24 | | 2017 | 8 | 11 | 19 | | 2018 | 11 | 10 | 21 | | 2019 | 10 | 9 | 19 | | 2020 | 6 | 16 | 22 | | 2021 | 8 | 9 | 17 | | 2022 | 3 | 15 | 18 | | 2023 | 1 | 10 | 11 | | 2024 | 6 | 13 | 19 | | 2025 | 9 | 13 | 22 | | 2026 | 3 | 2 | 5 |
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Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.
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Keane L, ?kandík M, Posada-Pérez M, Bose R, Desito J, van der Linde E, Engskog-Vlachos P, Ceccatelli S, Green AL, Joseph B. Microglia in diffuse midline glioma contribute to extracellular matrix remodelling and cancer cell invasion. Cell Death Dis. 2026 May 30; 17(1).
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Zlotnick HM, Goddard DN, Calo CJ, Dhand AP, Davidson MD, Solsona-Pujol A, Makhoul JT, Weppner HK, Wong M, Scanzello CR, Hind LE, Burdick JA. Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model. Proc Natl Acad Sci U S A. 2026 May 19; 123(20):e2524677123.
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Beedle AEM, Sharma V, Oliver-De La Cruz J, Jaganathan A, Albajar-Sigalés A, Max Yavitt F, Bera K, Andreu I, Granero-Moya I, Zalvidea D, Kechagia Z, Wiche G, Trepat X, Ivaska J, Anseth KS, Shenoy VB, Roca-Cusachs P. Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton. Nat Mater. 2026 Jul; 25(7):1252-1263.
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Trindade D, Di Caprio N, Maurício AC, Alves N, Moura C, Burdick JA. Bioactive and Injectable Granular Hydrogels Incorporating Decellularized Extracellular Matrix. ACS Biomater Sci Eng. 2026 Mar 09; 12(3):1787-1798.
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Grandke F, Rishik S, Wagner V, Engel A, Ludwig N, Calcuttawala K, Kern F, Keller V, Krawczyk M, Stodieck L, Ferguson V, Roberts A, Meese E, Schaum N, Quake S, Wyss-Coray T, Keller A. MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways. Nat Commun. 2026 Feb 05; 17(1):1387.
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Signoretti C, Fatehi S, Drewes R, Cendali F, Dzieciatkowska M, D'Alessandro A, Bae Y, Gupte SA. Bleomycin-induced lung fibrosis and dysfunction is exacerbated by G6PD deficiency. Am J Physiol Lung Cell Mol Physiol. 2026 02 01; 330(2):L145-L158.
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Reeser RS, VeDepo MC, Hewawasam RS, Waugh KA, Schade KA, Abdel-Hafiz M, Peña B, Mestroni L, Sbaizero O, Espinosa JM, Magin CM, Jacot JG. Aberrant tissue mechanics and mechanotransduction during heart development in down syndrome. J Biomech. 2026 Jan; 195:113103.
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Ginocchio S, McCabe MC, Flockton AR, Gumina DL, Hansen KC, Ji S, Su EJ. Unraveling the Matrix: Proteomic Profiling Reveals Stromal ECM Dysregulation in Severe Early-Onset Fetal Growth Restriction. Int J Mol Sci. 2025 Nov 19; 26(22).
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Schott CA, Redente EF. Pathogenic expansion: fibroblast proliferation fuels fibrosis. J Clin Invest. 2025 11 17; 135(22).
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Calo CJ, Radke M, Patil T, Hind LE. Regulation of neutrophil function by the extracellular matrix. Biochem Soc Trans. 2025 10 29; 53(5):1325-1336.
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