 Mitogen-Activated Protein Kinase 14
"Mitogen-Activated Protein Kinase 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
| Descriptor ID |
D048308
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.843.937 D12.644.360.450.835.800 D12.776.476.450.835.937
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| Concept/Terms |
Mitogen-Activated Protein Kinase 14- Mitogen-Activated Protein Kinase 14
- Mitogen Activated Protein Kinase 14
- CSAID-Binding Protein
- CSAID Binding Protein
- Kinase CSBP
- CSBP, Kinase
- p38alpha MAP Kinase
- MAP Kinase, p38alpha
- p38alphaMAPK
- Cytokine Suppressive Anti-inflammatory Drug Binding Protein
- Cytokine Suppressive Anti inflammatory Drug Binding Protein
- Mxi2 Protein
- MAX-Interacting Protein 2
- MAX Interacting Protein 2
- p38alpha Mitogen-Activated Protein Kinase
- p38alpha Mitogen Activated Protein Kinase
- MAPK14
- Stress-activated protein kinase 2a
- Stress activated protein kinase 2a
- SAPK2a
- MAPK14 Mitogen-Activated Protein Kinase
- MAPK14 Mitogen Activated Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 14".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 14".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 14" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 14" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 14" by people in Profiles.
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Judge DP, Lakdawala NK, Taylor MRG, Mestroni L, Li H, Oliver C, Angeli FS, Lee PA, MacRae CA. Long-Term Efficacy and Safety of ARRY-371797 (PF-07265803) in Patients With Lamin A/C-Related Dilated Cardiomyopathy. Am J Cardiol. 2022 11 15; 183:93-98.
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Patel NR, Cunoosamy DM, Fager?s M, Taib Z, Asimus S, Hegelund-Myrb?ck T, Lundin S, Pardali K, Kurian N, Ersdal E, Kristensson C, Korsback K, Palm?r R, Brown MN, Greenaway S, Siew L, Clarke GW, Rennard SI, Make BJ, Wise RA, Jansson P. The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial. Int J Chron Obstruct Pulmon Dis. 2018; 13:1009-1019.
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Stratton MS, Koch KA, McKinsey TA. p38a: A Profibrotic Signaling Nexus. Circulation. 2017 08 08; 136(6):562-565.
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Slattery ML, Lundgreen A, John EM, Torres-Mejia G, Hines L, Giuliano AR, Baumgartner KB, Stern MC, Wolff RK. MAPK genes interact with diet and lifestyle factors to alter risk of breast cancer: the Breast Cancer Health Disparities Study. Nutr Cancer. 2015; 67(2):292-304.
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Bernet JD, Doles JD, Hall JK, Kelly Tanaka K, Carter TA, Olwin BB. p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat Med. 2014 Mar; 20(3):265-71.
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McNamee EN, Collins CB, Lebsack MD, Rivera-Nieves J. Cell-specific inhibition of p38alpha as a therapeutic strategy for inflammatory bowel disease. Gastroenterology. 2010 Apr; 138(4):1237-9.
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Sours KM, Kwok SC, Rachidi T, Lee T, Ring A, Hoofnagle AN, Resing KA, Ahn NG. Hydrogen-exchange mass spectrometry reveals activation-induced changes in the conformational mobility of p38alpha MAP kinase. J Mol Biol. 2008 Jun 20; 379(5):1075-93.
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Jones NC, Tyner KJ, Nibarger L, Stanley HM, Cornelison DD, Fedorov YV, Olwin BB. The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell. J Cell Biol. 2005 Apr 11; 169(1):105-16.
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