 Molecular Targeted Therapy
"Molecular Targeted Therapy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.
| Descriptor ID |
D058990
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| MeSH Number(s) |
E02.319.574
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| Concept/Terms |
Molecular Targeted Therapy- Molecular Targeted Therapy
- Molecular Targeted Therapies
- Targeted Therapies, Molecular
- Targeted Therapy, Molecular
- Therapies, Molecular Targeted
- Therapy, Molecular Targeted
- Targeted Molecular Therapy
- Molecular Therapies, Targeted
- Molecular Therapy, Targeted
- Targeted Molecular Therapies
- Therapies, Targeted Molecular
- Therapy, Targeted Molecular
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Below are MeSH descriptors whose meaning is more general than "Molecular Targeted Therapy".
Below are MeSH descriptors whose meaning is more specific than "Molecular Targeted Therapy".
This graph shows the total number of publications written about "Molecular Targeted Therapy" by people in this website by year, and whether "Molecular Targeted Therapy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 3 | 2 | 5 | | 2011 | 5 | 10 | 15 | | 2012 | 6 | 6 | 12 | | 2013 | 15 | 8 | 23 | | 2014 | 15 | 14 | 29 | | 2015 | 9 | 22 | 31 | | 2016 | 10 | 20 | 30 | | 2017 | 6 | 28 | 34 | | 2018 | 10 | 20 | 30 | | 2019 | 5 | 23 | 28 | | 2020 | 2 | 13 | 15 | | 2021 | 5 | 7 | 12 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 2 | 2 | | 2024 | 1 | 14 | 15 | | 2025 | 7 | 5 | 12 | | 2026 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Molecular Targeted Therapy" by people in Profiles.
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Shah NJ, Sura S, Shinde R, Dai W, Wentworth C, Conkling P, Bupathi M, Vickery D, Perini R, Motzer RJ. Real-world treatment patterns and clinical outcomes among patients with metastatic renal cell carcinoma post immune-oncology and vascular endothelial growth factor receptor targeted therapies: A multicenter community oncology-based study. Urol Oncol. 2026 Apr; 44(4):110979.
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Davis AE, Rhoads S, Wechsler ME. Emerging biologic targets in type 2 and non-type 2 asthma. Curr Opin Pulm Med. 2026 May 01; 32(3):210-219.
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Agulnik M, Wilky BA, Thorpe SW, Zuckerman LM. Chondrosarcoma: Clinical behavior, molecular mechanisms, and emerging therapeutic strategies. Crit Rev Oncol Hematol. 2026 Feb; 218:105075.
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Schreiber AR, Verduzco-Aguirre HC, Giangiuli S, Aranda-Gutierrez A, Roy S, Soto-Perez-de-Celis E. A review of current and emerging therapies in breast cancer: implications for older adults. Expert Rev Clin Pharmacol. 2025 Oct; 18(10):1-16.
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Mukherjee N, Sheetz J, Shellman YG. Targeting the BCL2 Family: Advances and Challenges in BH3 Mimetic-Based Therapies. Int J Mol Sci. 2025 Oct 10; 26(20).
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Zhou X, Moreira S, Restelli C, Wang H, Jahangiri S, Aryal S, Tsao E, Zhang P, Niu M, Kumar H, Balde Z, Vujovic A, Liu L, Wong N, Arruda A, Minden MD, Zhou Y, Ravi B, Qi J, Li C, Hope KJ, Lu R. Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models. Sci Transl Med. 2025 Aug 06; 17(810):eadn5400.
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Menchaca AD, Srivatsa S, Kieran K, Fialkowski E, Soto A, Tracy ET, Romao RL, Kotagal M, Malek MM, Murphy AJ, Glick RD, Armstrong A, Cost NG, Aldrink JH. What Every Pediatric Surgeon Should Know About Common Systemic Therapies for the Treatment of Renal Tumors in Children and Adolescents. J Pediatr Surg. 2025 Sep; 60(9):162425.
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Soragni A, Knudsen ES, O'Connor TN, Tognon CE, Tyner JW, Gini B, Kim D, Bivona TG, Zang X, Witkiewicz AK, Goodrich DW, Jiang D, Gammon ST, Willey CD, Boutros PC, Sandulache VC, Osman AA, Myers JN, Mehla K, Singh PK, Chan KS, Gao H, Marathe H. Acquired resistance in cancer: towards targeted therapeutic strategies. Nat Rev Cancer. 2025 Aug; 25(8):613-633.
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Secord AA, Bae-Jump V, Backes F, Thaker P, Gehrig PA, Previs RA, Borden L, Thomas SM, Jackson A, Konecny GE, Duska LR, Arend R, Wright J, Corr B, Maxwell GL, Cosgrove CM, Mullen MM, Washington C, Herzog TJ, Cohen J, Hou J, Gaillard S, Fader AN, Berchuck A, Pothuri B. Genomic alterations, molecularly targeted therapy, and survival: a real-world Endometrial Cancer Molecularly Targeted Therapy Consortium cohort study. Int J Gynecol Cancer. 2025 May; 35(5):101758.
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Glushko T, Costello J, Chima R, McGettigan M, Kim R, Jeong D, Qayyum A. Molecular signatures of intrahepatic cholangiocarcinoma: role in targeted therapy selection. Eur J Radiol. 2025 Jun; 187:112056.
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