 Macrophages
"Macrophages" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
| Descriptor ID |
D008264
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| MeSH Number(s) |
A11.329.372 A11.627.482 A11.733.397 A15.382.680.397 A15.382.812.522
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| Concept/Terms |
Macrophages- Macrophages
- Bone Marrow-Derived Macrophages
- Bone Marrow Derived Macrophages
- Bone Marrow-Derived Macrophage
- Macrophage, Bone Marrow-Derived
- Macrophages, Bone Marrow-Derived
- Monocyte-Derived Macrophages
- Monocyte Derived Macrophages
- Macrophage
- Macrophages, Monocyte-Derived
- Macrophage, Monocyte-Derived
- Macrophages, Monocyte Derived
- Monocyte-Derived Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophages".
Below are MeSH descriptors whose meaning is more specific than "Macrophages".
This graph shows the total number of publications written about "Macrophages" by people in this website by year, and whether "Macrophages" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 2 | 4 | 6 | | 1997 | 6 | 1 | 7 | | 1998 | 10 | 6 | 16 | | 1999 | 4 | 7 | 11 | | 2000 | 6 | 6 | 12 | | 2001 | 12 | 3 | 15 | | 2002 | 6 | 12 | 18 | | 2003 | 7 | 9 | 16 | | 2004 | 4 | 15 | 19 | | 2005 | 7 | 12 | 19 | | 2006 | 13 | 13 | 26 | | 2007 | 16 | 18 | 34 | | 2008 | 17 | 21 | 38 | | 2009 | 9 | 19 | 28 | | 2010 | 15 | 18 | 33 | | 2011 | 19 | 21 | 40 | | 2012 | 24 | 10 | 34 | | 2013 | 16 | 20 | 36 | | 2014 | 17 | 19 | 36 | | 2015 | 22 | 17 | 39 | | 2016 | 24 | 23 | 47 | | 2017 | 23 | 17 | 40 | | 2018 | 22 | 14 | 36 | | 2019 | 26 | 16 | 42 | | 2020 | 21 | 27 | 48 | | 2021 | 20 | 15 | 35 | | 2022 | 3 | 16 | 19 | | 2023 | 6 | 32 | 38 | | 2024 | 18 | 29 | 47 | | 2025 | 23 | 14 | 37 |
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Below are the most recent publications written about "Macrophages" by people in Profiles.
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Gonçalves SM, Leite L, de Vasconcelos P, Pereira I, Dewi IMW, Mercier T, Aerts R, Ligeiro D, Mendes F, Freitas F, Condeço J, Vieira J, Espada E, Lagrou K, Maertens JA, Gresnigt MS, Dinarello CA, Lacerda JF, Pinho Vaz C, Cunha C, Carvalho A, van de Veerdonk FL. A Functional Polymorphism in IL-36ß Modulates Macrophage Antifungal Effector Functions and Increases Susceptibility to Invasive Pulmonary Aspergillosis. J Infect Dis. 2025 Nov 14; 232(5):1208-1219.
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VanderVeen BN, Cardaci TD, Unger CA, NeSmith MM, Freeman JC, Bastian AV, Roark K, Upadhyay M, Levy AG, Bullard BM, McDonald SJ, Velázquez KT, Enos RT, Kubinak JL, Hofseth LJ, Hebert JR, Fan D, Murphy EA. Cannabis improves metabolic dysfunction and macrophage signatures in obese mice. Am J Physiol Cell Physiol. 2025 Oct 01; 329(4):C1316-C1331.
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Cardaci TD, Bastian AV, Roark K, Bullard BM, NeSmith MM, Unger CA, Price RL, Kubinak JL, Murphy EA, VanderVeen BN. Profibrotic immune cells and fibro-adipogenic progenitors contribute to skeletal muscle extracellular matrix remodeling and fibrosis in cancer cachexia. Am J Physiol Cell Physiol. 2025 Oct 01; 329(4):C1283-C1299.
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Raj RR, Day NB, Loomis NE, Cutting E, Gupta A, Wyatt Shields C. Transport of Adoptive Cell Transfers With Magnetic Helical Microrobots. Small. 2025 Oct; 21(42):e05946.
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Lakshmanachetty S, Riemondy K, Sanford B, Donson A, Chen V, Balakrishnan I, Prince EW, Hankinson T, Dahl N, Vibhakar R, Foreman N, Venkatraman S, Mitra SS. Differential phagocytosis induces diverse macrophage activation states in malignant gliomas. J Immunother Cancer. 2025 Sep 05; 13(9).
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Bersie SM, McCubbrey AL. Heterogeneity of Lung Phagocytes and Clearance of Apoptotic Cells in Lung Injury and Repair. Semin Respir Crit Care Med. 2025 Aug; 46(4):311-321.
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Lu SL, Chen S, Noda K, Li Y, Tsai CY, Omori H, Kato Y, Zhang Z, Chen B, Tokuda K, Zheng T, Wakita M, Hara E, Fukuda M, Wada Y, Morita E, Uzawa N, Murakami S, Noda T. Evidence that mitochondria in macrophages are destroyed by microautophagy. Nat Commun. 2025 Aug 30; 16(1):8123.
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Karl R, Ashraf APK, Viola MF, Hopp K, Mass E, Wachten D. Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. J Cell Sci. 2025 Oct 15; 138(20).
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Guo Z, Ataran A, Ma P, Yu W, Hajirezaei H, Valenzuela Ripoll C, Pedersen LN, Rashidi O, Chan MM, Shen M, Kelley S, Sargazi A, Ozcan M, Lotfinaghsh A, Cho Y, Diab A, Grogan F, Klaas A, Pompian A, Imam A, Lodhi R, Zelleke AB, Kovacs A, Margulies KB, Szymanski J, Sardiello M, Razani B, Asnani A, Kopecky BJ, Signore PE, Yi BA, Basson CT, Ravichandran KS, Prabhu SD, Bergom C, Schilling JD, Lavine KJ, Javaheri A. Human Single-Nucleus RNA Sequencing Identifies CD47 as a Therapeutic Target for Doxorubicin-Induced Cardiomyopathy. Circulation. 2025 Sep 09; 152(10):661-681.
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Kwan MMC, Day NB, Konigsberg IR, Thoresen E, Harrell AG, Busch CE, Davidson EJ, Yang IV, Shields CW. Particle Shape Modulates the Function of Adoptive Macrophage Transfers. Adv Healthc Mater. 2025 Dec; 14(31):e01348.
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