 Macrophages
"Macrophages" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
| Descriptor ID |
D008264
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| MeSH Number(s) |
A11.329.372 A11.627.482 A11.733.397 A15.382.680.397 A15.382.812.522
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| Concept/Terms |
Macrophages- Macrophages
- Bone Marrow-Derived Macrophages
- Bone Marrow Derived Macrophages
- Bone Marrow-Derived Macrophage
- Macrophage, Bone Marrow-Derived
- Macrophages, Bone Marrow-Derived
- Monocyte-Derived Macrophages
- Monocyte Derived Macrophages
- Macrophage
- Macrophages, Monocyte-Derived
- Macrophage, Monocyte-Derived
- Macrophages, Monocyte Derived
- Monocyte-Derived Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophages".
Below are MeSH descriptors whose meaning is more specific than "Macrophages".
This graph shows the total number of publications written about "Macrophages" by people in this website by year, and whether "Macrophages" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 10 | 3 | 13 | | 1996 | 3 | 3 | 6 | | 1997 | 6 | 1 | 7 | | 1998 | 10 | 5 | 15 | | 1999 | 4 | 7 | 11 | | 2000 | 6 | 6 | 12 | | 2001 | 12 | 3 | 15 | | 2002 | 7 | 12 | 19 | | 2003 | 7 | 9 | 16 | | 2004 | 4 | 15 | 19 | | 2005 | 7 | 12 | 19 | | 2006 | 12 | 13 | 25 | | 2007 | 15 | 19 | 34 | | 2008 | 17 | 20 | 37 | | 2009 | 9 | 19 | 28 | | 2010 | 15 | 18 | 33 | | 2011 | 18 | 21 | 39 | | 2012 | 24 | 10 | 34 | | 2013 | 16 | 21 | 37 | | 2014 | 17 | 19 | 36 | | 2015 | 23 | 17 | 40 | | 2016 | 21 | 21 | 42 | | 2017 | 23 | 17 | 40 | | 2018 | 21 | 14 | 35 | | 2019 | 23 | 16 | 39 | | 2020 | 20 | 25 | 45 | | 2021 | 19 | 15 | 34 | | 2022 | 2 | 13 | 15 | | 2023 | 4 | 30 | 34 | | 2024 | 18 | 24 | 42 | | 2025 | 14 | 7 | 21 |
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Below are the most recent publications written about "Macrophages" by people in Profiles.
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Elajaili H, Lyttle BD, Lewis CV, Bardill JR, Dee N, Seal S, Nozik ES, Liechty KW, Zgheib C. Increased ROS and Persistent Pro-Inflammatory Responses in a Diabetic Wound Healing Model (db/db): Implications for Delayed Wound Healing. Int J Mol Sci. 2025 May 20; 26(10).
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Lewis CV, Nguyen TN, Porfilio TE, Burciaga SD, Posey JN, Jordan M, Colon Hidalgo D, Stenmark KR, Mickael C, Sul C, Oberley-Deegan RE, Delaney C, Nozik ES. Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia. Am J Physiol Lung Cell Mol Physiol. 2025 Jun 01; 328(6):L885-L900.
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Maserumule C, Passemar C, Oh OSH, Hegyi K, Brown K, Weimann A, Dinan A, Davila S, Klapholz C, Bryant J, Verma D, Gadwa J, Krishnananthasivam S, Vongtongsalee K, Kendall E, Trelles A, Hibberd ML, Sanz J, Bertol J, V?zquez-Iniesta L, Andi K, Kumar SS, Ordway D, Prados-Rosales R, MacAry PA, Floto RA. Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis. Cell Rep. 2025 May 27; 44(5):115657.
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Fukuda R, Fujiwara Y, Maeda H, Pan C, Minayoshi Y, Yano H, Mizuta Y, Takano M, Yamada R, Saito Y, Hirata K, Imoto S, Yamasaki K, Oniki K, Saruwatari J, Otagiri M, Watanabe H, Komohara Y, Maruyama T. Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages. Mol Cancer. 2025 May 03; 24(1):132.
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Gong J, Chan KS, Rajesh A, Droho S, Lavine JA. Adrb2 Expression in Ocular-Infiltrating Macrophages Is Necessary for Interleukin-6 Expression and Choroidal Neovascularization. Invest Ophthalmol Vis Sci. 2025 May 01; 66(5):43.
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Haggett JG, Dinesh Kumar G, Melville MJ, Johansen CG, Knudson LD, Farnsworth NL, Domaille DW. A Diazaborine Activity-Based Sensing Fluorescent Probe Reports Endogenously Produced Mitochondrial Peroxynitrite in Live Macrophages. Chembiochem. 2025 Apr 01; 26(7):e202400972.
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Bhattacharya M, Scherr TD, Lister J, Kielian T, Horswill AR. Extracellular adherence proteins reduce matrix porosity and enhance Staphylococcus aureus biofilm survival during prosthetic joint infection. Infect Immun. 2025 Apr 08; 93(4):e0008625.
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Fry LG, Washam CL, Roys H, Bowlin AK, Venugopal G, Bird JT, Byrum SD, Weinkopff T. HIF-a signaling regulates the macrophage inflammatory response during Leishmania major infection. Front Immunol. 2025; 16:1487311.
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Hill JH, Bell R, Barrios L, Baird H, Ost K, Greenewood M, Monts JK, Tracy E, Meili CH, Chiaro TR, Weis AM, Guillemin K, Beaudin AE, Murtaugh LC, Stephens WZ, Round JL. Neonatal fungi promote lifelong metabolic health through macrophage-dependent ? cell development. Science. 2025 Mar 07; 387(6738):eadn0953.
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Gross PS, Dur?n-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
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