 Mitochondria
"Mitochondria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D008928
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| MeSH Number(s) |
A11.284.430.214.190.875.564 A11.284.835.626
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| Concept/Terms |
Mitochondrial Contraction- Mitochondrial Contraction
- Contraction, Mitochondrial
- Contractions, Mitochondrial
- Mitochondrial Contractions
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Below are MeSH descriptors whose meaning is more general than "Mitochondria".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria".
This graph shows the total number of publications written about "Mitochondria" by people in this website by year, and whether "Mitochondria" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 1 | 4 | | 1996 | 3 | 2 | 5 | | 1997 | 0 | 1 | 1 | | 1998 | 3 | 0 | 3 | | 1999 | 5 | 1 | 6 | | 2000 | 6 | 4 | 10 | | 2001 | 3 | 3 | 6 | | 2002 | 6 | 6 | 12 | | 2003 | 6 | 3 | 9 | | 2004 | 10 | 7 | 17 | | 2005 | 6 | 9 | 15 | | 2006 | 9 | 4 | 13 | | 2007 | 5 | 11 | 16 | | 2008 | 10 | 15 | 25 | | 2009 | 8 | 7 | 15 | | 2010 | 10 | 4 | 14 | | 2011 | 12 | 3 | 15 | | 2012 | 19 | 8 | 27 | | 2013 | 18 | 10 | 28 | | 2014 | 16 | 12 | 28 | | 2015 | 22 | 11 | 33 | | 2016 | 19 | 11 | 30 | | 2017 | 14 | 17 | 31 | | 2018 | 16 | 22 | 38 | | 2019 | 16 | 9 | 25 | | 2020 | 18 | 16 | 34 | | 2021 | 20 | 20 | 40 | | 2022 | 3 | 16 | 19 | | 2023 | 2 | 14 | 16 | | 2024 | 17 | 7 | 24 | | 2025 | 4 | 8 | 12 |
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Below are the most recent publications written about "Mitochondria" by people in Profiles.
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Sabbah HN, Alder NN, Sparagna GC, Bruce JE, Stauffer BL, Chao LH, Pitceathly RDS, Maack C, Marcinek DJ. Contemporary insights into elamipretide's mitochondrial mechanism of action and therapeutic effects. Biomed Pharmacother. 2025 Jun; 187:118056.
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Willett BAS, Thompson SB, Chen V, Dareshouri A, Jackson CL, Brunetti T, D'Alessandro A, Klarquist J, Nemkov T, Kedl RM. Mitochondrial protein OPA1 is required for the expansion of effector CD8 T cells. Cell Rep. 2025 May 27; 44(5):115610.
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Yegambaram M, Pokharel MD, Sun X, Lu Q, Soto J, Aggarwal S, Maltepe E, Fineman JR, Wang T, Black SM. Restoration of pp60Src Re-Establishes Electron Transport Chain Complex I Activity in Pulmonary Hypertensive Endothelial Cells. Int J Mol Sci. 2025 Apr 17; 26(8).
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Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Egan G, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs. Nature. 2025 Jun; 642(8067):421-430.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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Walker EM, Pearson GL, Lawlor N, Stendahl AM, Lietzke A, Sidarala V, Zhu J, Stromer T, Reck EC, Li J, Levi-D'Ancona E, Pasmooij MB, Hubers DL, Renberg A, Mohamed K, Parekh VS, Zhang IX, Thompson B, Zhang D, Ware SA, Haataja L, Qi N, Parker SCJ, Arvan P, Yin L, Kaufman BA, Satin LS, Sussel L, Stitzel ML, Soleimanpour SA. Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues. Science. 2025 04 11; 388(6743):eadf2034.
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Haggett JG, Dinesh Kumar G, Melville MJ, Johansen CG, Knudson LD, Farnsworth NL, Domaille DW. A Diazaborine Activity-Based Sensing Fluorescent Probe Reports Endogenously Produced Mitochondrial Peroxynitrite in Live Macrophages. Chembiochem. 2025 Apr 01; 26(7):e202400972.
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Turner JA, Katsnelson E, Torres RM. Measuring Mitochondrial Function of Na?ve and Effector CD8 T Cells. J Vis Exp. 2025 Mar 28; (217).
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Lo HG, Goering R, Kocere A, Lo J, Pockalny MC, White LK, Ramirez H, Martinez A, Jacobson S, Spitale RC, Pearson CG, Resendiz MJE, Mosimann C, Taliaferro JM. Quantification of subcellular RNA localization through direct detection of RNA oxidation. Nucleic Acids Res. 2025 Feb 27; 53(5).
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Henckel MM, Chun JH, Knaub LA, Pott GB, James GE, Hunter KS, Shandas R, Walker LA, Reusch JE, Keller AC. Thermoneutral-housed rats demonstrate impaired perivascular adipose tissue and vascular crosstalk. J Hypertens. 2025 May 01; 43(5):752-767.
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