Mitochondria
"Mitochondria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D008928
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| MeSH Number(s) |
A11.284.430.214.190.875.564 A11.284.835.626
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| Concept/Terms |
Mitochondrial Contraction- Mitochondrial Contraction
- Contraction, Mitochondrial
- Contractions, Mitochondrial
- Mitochondrial Contractions
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Below are MeSH descriptors whose meaning is more general than "Mitochondria".
Below are MeSH descriptors whose meaning is more specific than "Mitochondria".
This graph shows the total number of publications written about "Mitochondria" by people in this website by year, and whether "Mitochondria" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 3 | 6 | | 1997 | 1 | 1 | 2 | | 1998 | 3 | 0 | 3 | | 1999 | 5 | 1 | 6 | | 2000 | 5 | 4 | 9 | | 2001 | 3 | 3 | 6 | | 2002 | 6 | 7 | 13 | | 2003 | 6 | 3 | 9 | | 2004 | 10 | 8 | 18 | | 2005 | 7 | 10 | 17 | | 2006 | 9 | 4 | 13 | | 2007 | 6 | 11 | 17 | | 2008 | 12 | 15 | 27 | | 2009 | 9 | 7 | 16 | | 2010 | 10 | 6 | 16 | | 2011 | 15 | 5 | 20 | | 2012 | 21 | 9 | 30 | | 2013 | 19 | 13 | 32 | | 2014 | 17 | 13 | 30 | | 2015 | 25 | 12 | 37 | | 2016 | 21 | 13 | 34 | | 2017 | 15 | 19 | 34 | | 2018 | 18 | 26 | 44 | | 2019 | 18 | 9 | 27 | | 2020 | 18 | 17 | 35 | | 2021 | 21 | 20 | 41 | | 2022 | 3 | 18 | 21 | | 2023 | 3 | 13 | 16 | | 2024 | 18 | 8 | 26 | | 2025 | 19 | 21 | 40 | | 2026 | 1 | 2 | 3 |
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Below are the most recent publications written about "Mitochondria" by people in Profiles.
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Murray KO, Gioscia-Ryan RA, Justice JN, Santos-Parker JR, Bispham NZ, Hutton DA, Darvish S, Miyamoto-Ditmon J, Clayton ZS, Chonchol M, Seals DR, Rossman MJ. Translational studies of chronic supplementation with a mitochondria-targeted antioxidant to improve physical function with ageing. J Physiol. 2026 Apr; 604(7):2898-2922.
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Bertino F, Zanin Venturini DI, Grasso E, Kopecka J, Salio C, Gnutti B, Basnet RM, Bellini S, Mignani L, Zhao B, Kleefeld F, Hentschel A, Magnani F, Fiorito V, Abalai RE, Metani L, Allocco AL, Petrillo S, De Giorgio F, Ammirata G, Salsano E, Pareyson D, di Rocco M, Abicht A, McCourt E, Horvath R, Kölbel H, Larson A, Roos A, Yu TW, Finazzi D, Riganti C, Tolosano E, Chiabrando D. Mitochondrial energetic failure underlies FLVCR1-related sensory neuropathy. Commun Biol. 2026 Feb 14; 9(1).
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Day BJ. Immunometabolism: Is cyanide a missing link between metabolic pathways and immune function? Biochem Pharmacol. 2026 Mar; 245:117694.
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Sessions DT, Boulton DP, Spoelstra NS, Caino MC, Yu M, Goodspeed A, Richer JK. Androgen Receptors Promote Oxidative Phosphorylation and Resistance to Palmitate Lipotoxicity in ER-Mutant Breast Cancer. Endocrinology. 2025 Dec 05; 167(1).
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Shimada H, Sakuragi T, Barentsen K, Erickson K, Urschitz J, Powell TL, Jansson T, Rosario FJ. Placental mitochondrial respiration is inhibited in mice with trophoblast specific AdipoR2 overexpression. Free Radic Biol Med. 2026 Feb 01; 243:276-290.
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Singh AK, D'Alessandro A, Wellendorf AM, Gonzalez-Nieto D, Kofron M, Dzieciatkowska M, Mejia L, Barrio LC, Filippi MD, Cancelas JA. Metabolic adaptation of regenerative hematopoiesis depends on docking-independent mitochondrial connexin 43. Blood. 2025 Nov 06; 146(19):2306-2321.
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Jenkins BJ, Jenkins YR, Ponce-Garcia FM, Moscrop C, Perry IA, Hitchings MD, Uribe AH, Bernuzzi F, Eastham S, Cronin JG, Berisha A, Howell A, Davies J, Blagih J, Williams M, Marsden M, Veale DJ, Davies LC, Niphakis M, Finlay DK, Sinclair LV, Cravatt BF, Hogan AE, Nathan JA, Humphreys IR, Fearon U, Sumpton D, Vande Voorde J, Vale GDD, McDonald JG, Jones GW, Pearson JA, Vincent EE, Jones N. Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function. Nat Commun. 2025 Nov 03; 16(1):9484.
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Liu T, Zhou JH, Gong Y, Zhang Y, Ma Y, Zhang X, Minhajuddin M, Song W, Zhuang Z, Vujovic A, Lu Y, Jia A, Guo R, Ren R, Zhou L, Xiong Y, Huang L, Du X, Zhao TJ, Li P, Jordan CT, Ye H. A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential. Cell Rep. 2025 Nov 25; 44(11):116496.
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Lindsey ARI, Tennessen JM, Gelaw MA, Jones MW, Parish AJ, Newton ILG, Nemkov T, D'Alessandro A, Rai M, Stark N. The intracellular symbiont Wolbachia alters Drosophila development and metabolism to buffer against nutritional stress. PLoS Genet. 2025 Oct; 21(10):e1011905.
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Affandi T, Ohm AM, Speidel JT, Caino MC, Boulton DP, Reyland ME. PKCd Regulates DNA Damage and Cell Death through a SIRT6/Nrf2-dependent Antioxidant Response. Mol Cancer Res. 2025 Sep 04; 23(9):779-791.
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