MicroRNAs
"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Descriptor ID |
D035683
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MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
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Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
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Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 2 | 0 | 2 | 2006 | 0 | 2 | 2 | 2007 | 4 | 0 | 4 | 2008 | 6 | 2 | 8 | 2009 | 7 | 1 | 8 | 2010 | 17 | 5 | 22 | 2011 | 20 | 8 | 28 | 2012 | 25 | 6 | 31 | 2013 | 24 | 7 | 31 | 2014 | 27 | 13 | 40 | 2015 | 24 | 9 | 33 | 2016 | 16 | 8 | 24 | 2017 | 25 | 6 | 31 | 2018 | 24 | 5 | 29 | 2019 | 17 | 7 | 24 | 2020 | 19 | 6 | 25 | 2021 | 15 | 5 | 20 | 2022 | 19 | 1 | 20 | 2023 | 16 | 0 | 16 | 2024 | 13 | 3 | 16 | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Haddad G, Blaine J. miR-204-5p Protects Nephrin from Enzymatic Degradation in Cultured Mouse Podocytes Treated with Nephrotoxic Serum. Cells. 2025 03 01; 14(5).
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Levy MV, Fandl HK, Hijmans JG, Stockelman KA, Ruzzene ST, Reiakvam WR, Goldthwaite ZA, Greiner JJ, DeSouza CA, Garcia VP. Effect of 17?-Estradiol on Endothelial Cell Expression of Inflammation- Related MicroRNA. Microrna. 2025; 14(1):3-8.
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Flynn CL, Markey GE, Neudecker V, Farrelly C, Furuta GT, Eltzschig HK, Masterson JC, McNamee EN. The MicroRNA miR-223 Constrains Colitis-associated Tumorigenesis by Limiting Myeloid Cell Infiltration and Chemokine Expression. J Immunol. 2024 Dec 15; 213(12):1869-1883.
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Holzhausen EA, Patterson WB, Wong BH, Kim S, Kupsco A, Howe CG, Bode L, Goran MI, Alderete TL. Associations between human milk EV-miRNAs and oligosaccharide concentrations in human milk. Front Immunol. 2024; 15:1463463.
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Bardill JR, Karimpour-Fard A, Breckenfelder CC, Sucharov CC, Eason CR, Gallagher LT, Khailova L, Wright CJ, Gien J, Galan HL, Derderian SC. microRNAs in congenital diaphragmatic hernia: insights into prenatal and perinatal biomarkers and altered molecular pathways. Am J Obstet Gynecol MFM. 2024 Dec; 6(12):101535.
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Subramanian C, McNamara K, Croslow SW, Tan Y, Hess D, Kiseljak-Vassiliades K, Wierman ME, Sweedler JV, Cohen MS. Novel repurposing of sulfasalazine for the treatment of adrenocortical carcinomas, probably through the SLC7A11/xCT-hsa-miR-92a-3p-OIP5-AS1 network pathway. Surgery. 2025 01; 177:108832.
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Welle TM, Rajgor D, Kareemo DJ, Garcia JD, Zych SM, Wolfe SE, Gookin SE, Martinez TP, Dell'Acqua ML, Ford CP, Kennedy MJ, Smith KR. miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity. EMBO Rep. 2024 Nov; 25(11):5141-5168.
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Czopik AK, McNamee EN, Vaughn V, Huang X, Bang IH, Clark T, Wang Y, Ruan W, Nguyen T, Masterson JC, Tak E, Frank S, Collins CB, Li H, Rodriguez-Aguayo C, Lopez-Berestein G, Gerich ME, Furuta GT, Yuan X, Sood AK, de Zoeten EF, Eltzschig HK. HIF-2a-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis. Nat Commun. 2024 Sep 14; 15(1):8042.
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Eckhardt CM, Wu H, Jackson G, Sobel MH, Bloomquist T, Divjan A, da Silva H, Best LG, Cole S, Umans J, Zhang Y, de Hoff P, Laurent LC, Perzanowski MS, Cheng K, Baccarelli AA, Sanchez TR. Extracellular Vesicle-Encapsulated microRNAs and Respiratory Health Among American Indian Participants in the Strong Heart Study. Chest. 2025 Jan; 167(1):87-97.
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Konigsberg IR, Lin NW, Liao SY, Liu C, MacPhail K, Mroz MM, Davidson E, Restrepo CI, Sharma S, Li L, Maier LA, Yang IV. Multi-omic signatures of sarcoidosis and progression in bronchoalveolar lavage cells. Respir Res. 2024 Jul 30; 25(1):289.
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