 MicroRNAs
"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
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| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
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| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
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Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 4 | 0 | 4 | | 2008 | 6 | 2 | 8 | | 2009 | 7 | 1 | 8 | | 2010 | 19 | 5 | 24 | | 2011 | 20 | 10 | 30 | | 2012 | 25 | 6 | 31 | | 2013 | 21 | 6 | 27 | | 2014 | 26 | 13 | 39 | | 2015 | 22 | 9 | 31 | | 2016 | 17 | 8 | 25 | | 2017 | 28 | 6 | 34 | | 2018 | 27 | 5 | 32 | | 2019 | 17 | 5 | 22 | | 2020 | 19 | 6 | 25 | | 2021 | 15 | 6 | 21 | | 2022 | 20 | 1 | 21 | | 2023 | 18 | 0 | 18 | | 2024 | 17 | 5 | 22 | | 2025 | 7 | 4 | 11 | | 2026 | 3 | 4 | 7 |
To return to the timeline, click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Jackson G, Islam H, de Souza Teixeira AA, DeSouza C, Li ITS, Little J. Sex differences in circulating platelet-derived CD41+ extracellular vesicles in healthy adults. Physiol Rep. 2026 Jul; 14(13):e70932.
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Xia X, Paul A, Zhang R, Kurlbaum M, Kiseljak-Vassiliades K, Reincke M, Sbiera S, Riester A, Vetrivel S. miR-486-5p and miR-144-3p as candidate regulators of cortisol biosynthesis: functional and transcriptomic evidence in adrenocortical cells. Eur J Endocrinol. 2026 Jul 01; 195(1):152-164.
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Shadid A, Rich HE, Hok KD, Doursout MF, Restrepo MI, Banda NK, Gunamalai L, Shivshankar P. Comprehensive Prediction Analysis of Novel Noncoding Regulatory Variants Identified in the MicroRNA Binding Regions in Complement System Genes. Int J Mol Sci. 2026 Jun 30; 27(13).
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Goel K, Ormesher R, Pratte KA, Wang Y, Nishino K, Hersh CP, Kechris K, Bowler RP, Petrache I. Vascular-related proteomic signatures in COPD with suspected pulmonary hypertension as predictors of FEV1 impairment. Respir Res. 2026 Mar 28; 27(1).
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Chakraborty N, Patel M, Kannan S, Moyler C, Dimitrov G, Gautam A, Newman M, Hendry-Hofer TB, Boyd J, Hammamieh R. Fentanyl-induced cortical and cardiopulmonary damage linked to immune response functions and apoptosis-necrosis networks in a multi-omics mouse model. Front Immunol. 2026; 17:1694651.
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Jackson G, Islam H, de Souza Teixeira AA, Boultbee J, Marcotte-Chénard A, DeSouza C, Li ITS, Little J. Extracellular vesicles in type 2 diabetes exhibit elevated miR-155 cargo and Annexin A1 concentration. Life Sci. 2026 May 01; 392:124297.
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Grandke F, Rishik S, Wagner V, Engel A, Ludwig N, Calcuttawala K, Kern F, Keller V, Krawczyk M, Stodieck L, Ferguson V, Roberts A, Meese E, Schaum N, Quake S, Wyss-Coray T, Keller A. MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways. Nat Commun. 2026 Feb 05; 17(1):1387.
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Panda K, Peng JY, Santiago MJ, Rahman MS, Shaikh SB, Kaur G, Faizan MI, Islam KU, Wang T, Black SM, Evans CM, Rahman I, Chinnapaiyan S, Unwalla HJ. HIV disrupts the lung molecular clock, leading to lung inflammation and features of emphysema. Commun Biol. 2026 Jan 05; 9(1):11.
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Meza Monge K, Najarro KM, McMahan RH, Kovacs EJ, Idrovo JP. Subclinical Hepatic Injury and Dysfunction Following Surgery: Evidence From a Young and Aged Laparotomy Murine Model. FASEB J. 2025 Dec 31; 39(24):e71224.
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Vaughan OR, Goodspeed A, Sucharov CC, Powell TL, Jansson T. Human fetal circulating factors from pregnancies complicated by obesity upregulate genes associated with pathological hypertrophy in neonatal rat cardiomyocytes. Am J Physiol Heart Circ Physiol. 2026 01 01; 330(1):H124-H136.
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