MicroRNAs
"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
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| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
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| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
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Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 4 | 0 | 4 | | 2008 | 6 | 2 | 8 | | 2009 | 7 | 1 | 8 | | 2010 | 19 | 5 | 24 | | 2011 | 19 | 9 | 28 | | 2012 | 25 | 6 | 31 | | 2013 | 21 | 7 | 28 | | 2014 | 26 | 12 | 38 | | 2015 | 21 | 9 | 30 | | 2016 | 15 | 8 | 23 | | 2017 | 28 | 6 | 34 | | 2018 | 27 | 5 | 32 | | 2019 | 17 | 5 | 22 | | 2020 | 20 | 5 | 25 | | 2021 | 15 | 6 | 21 | | 2022 | 21 | 1 | 22 | | 2023 | 17 | 0 | 17 | | 2024 | 17 | 5 | 22 | | 2025 | 6 | 4 | 10 | | 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Grandke F, Rishik S, Wagner V, Engel A, Ludwig N, Calcuttawala K, Kern F, Keller V, Krawczyk M, Stodieck L, Ferguson V, Roberts A, Meese E, Schaum N, Quake S, Wyss-Coray T, Keller A. MiRNAs shape mouse age-independent tissue adaptation to spaceflight via ECM and developmental pathways. Nat Commun. 2026 Feb 05; 17(1):1387.
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Panda K, Peng JY, Santiago MJ, Rahman MS, Shaikh SB, Kaur G, Faizan MI, Islam KU, Wang T, Black SM, Evans CM, Rahman I, Chinnapaiyan S, Unwalla HJ. HIV disrupts the lung molecular clock, leading to lung inflammation and features of emphysema. Commun Biol. 2026 Jan 05; 9(1):11.
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Meza Monge K, Najarro KM, McMahan RH, Kovacs EJ, Idrovo JP. Subclinical Hepatic Injury and Dysfunction Following Surgery: Evidence From a Young and Aged Laparotomy Murine Model. FASEB J. 2025 Dec 31; 39(24):e71224.
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Vaughan OR, Goodspeed A, Sucharov CC, Powell TL, Jansson T. Human fetal circulating factors from pregnancies complicated by obesity upregulate genes associated with pathological hypertrophy in neonatal rat cardiomyocytes. Am J Physiol Heart Circ Physiol. 2026 Jan 01; 330(1):H124-H136.
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Ananthamohan K, Brady TM, Arif M, Daniels SR, Falkner B, Ferguson M, Flynn JT, Hanevold C, Hooper SR, Ingelfinger JR, Lande M, Martin LJ, Meyers KE, Mitsnefes M, Rosner B, Samuels JA, Kuffel G, Zilliox MJ, Chen QM, Becker RC, Urbina EM, Sadayappan S. A Multiomics Approach to Defining Target-Organ Injury in Youths With Primary Hypertension: The SHIP AHOY Cohort. J Am Heart Assoc. 2025 Nov 04; 14(21):e037649.
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Gu W, Langlois AWR, Giratallah H, Claw KG, Prasad B, Thummel KE, Tyndale RF. Extending Investigations of miR-126-5p on the Regulation of CYP2A6, the Major Nicotine-Inactivating Enzyme. Pharmacol Res Perspect. 2025 Aug; 13(4):e70149.
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Eckhardt CM, Li W, Bloomquist TR, Jackson G, Joglekar N, Liu Z, De Hoff P, Vokonas PS, Sparrow D, Laurent LC, Best LG, Cole S, Umans JG, Zhang Y, Domingo-Relloso A, Sanchez TR, Schwartz J, Cheng K, Navas-Acien A, Baccarelli AA, Wu H. Extracellular vesicle-encapsulated microRNA signatures of cigarette smoking and smoking-related harm. Respir Med. 2025 Sep; 246:108226.
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Jeffrey DA, Dockstader K, Revoredo Vicentino A, Slavov DB, Miyamoto SD, Stauffer BL, Sucharov CC. Muscle-specific isoforms of FXR1 are necessary for miR-1-mediated repression of connexin 43 and are downregulated in pediatric dilated cardiomyopathy. Am J Physiol Heart Circ Physiol. 2025 Jun 01; 328(6):H1380-H1390.
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Haddad G, Blaine J. miR-204-5p Protects Nephrin from Enzymatic Degradation in Cultured Mouse Podocytes Treated with Nephrotoxic Serum. Cells. 2025 03 01; 14(5).
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Bayraktar R, Tang Y, Dragomir MP, Ivan C, Peng X, Fabris L, Zhang J, Carugo A, Aneli S, Liu J, Chen MM, Srinivasan S, Sahnoune I, Bayraktar E, Akdemir KC, Chen M, Narayanan P, Huang W, Ott LF, Eterovic AK, Villarreal OE, Mohammad MM, Peoples MD, Walsh DM, Hernandez JA, Morgan MB, Shaw KR, Davis JS, Menter D, Tam CS, Yeh P, Dawson SJ, Rassenti LZ, Kipps TJ, Kunej T, Estrov Z, Joosse SA, Pagani L, Alix-Panabières C, Pantel K, Ferajoli A, Futreal A, Wistuba II, Radovich M, Kopetz S, Keating MJ, Draetta GF, Mattick JS, Liang H, Calin GA. The mutational landscape and functional effects of noncoding ultraconserved elements in human cancers. Sci Adv. 2025 Feb 21; 11(8):eado2830.
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