 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.679 G03.808
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 16 | 16 | | 1997 | 1 | 16 | 17 | | 1998 | 0 | 21 | 21 | | 1999 | 0 | 13 | 13 | | 2000 | 0 | 30 | 30 | | 2001 | 0 | 39 | 39 | | 2002 | 0 | 50 | 50 | | 2003 | 0 | 38 | 38 | | 2004 | 1 | 46 | 47 | | 2005 | 0 | 66 | 66 | | 2006 | 0 | 65 | 65 | | 2007 | 0 | 54 | 54 | | 2008 | 1 | 62 | 63 | | 2009 | 0 | 64 | 64 | | 2010 | 0 | 68 | 68 | | 2011 | 1 | 90 | 91 | | 2012 | 0 | 90 | 90 | | 2013 | 2 | 86 | 88 | | 2014 | 0 | 72 | 72 | | 2015 | 2 | 64 | 66 | | 2016 | 0 | 92 | 92 | | 2017 | 0 | 78 | 78 | | 2018 | 3 | 73 | 76 | | 2019 | 0 | 66 | 66 | | 2020 | 0 | 74 | 74 | | 2021 | 2 | 41 | 43 | | 2022 | 0 | 21 | 21 | | 2023 | 0 | 17 | 17 | | 2024 | 10 | 38 | 48 | | 2025 | 0 | 44 | 44 | | 2026 | 0 | 6 | 6 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Stein CS, Zhang X, Witmer NH, Pennington ER, Hahn S, Straub AC, Shaikh SR, Boudreau RL. Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischaemia-reperfusion injury. Cardiovasc Res. 2026 Mar 26; 122(3):379-396.
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Shao C, Indeglia A, Foster M, Casey K, Leung J, Modarai SR, Leu JI, Duong B, Mes-Masson AM, Sims-Mourtada J, Auslander N, Drapkin R, Bitler BG, Zhang N, Murphy ME. Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer. Genes Dev. 2026 Feb 02; 40(3-4):199-214.
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Zhang J, Bai X, Dai S, Chen Z. Structural study of Nicotiana benthamiana NADPH-dependent thioredoxin reductase C and its molecular mechanism of interaction with 2-Cys peroxiredoxin. Acta Crystallogr D Struct Biol. 2026 Feb 01; 82(Pt 2):126-139.
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Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Wan C, Wu J, Ouyang Y, Puscher H, Tian Y, Li S, Yin Q, Shen J. Regulation of AP1 adaptor assembly by the bi-handed chaperone MEA1. Nat Commun. 2026 01 20; 17(1).
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Talley WRK, Bazan D, Majewski J, Kaltner H, Vander Zanden CM. Structure of Two Tandem-Repeat Galectin Proteins Binding a Model Glycolipid Membrane. J Mol Biol. 2026 Mar 01; 438(5):169638.
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DeGolier KR, Pham-Danis C, Burciaga SD, Walsh ZH, Brzezinski C, Novak AJ, Leach L, Cimons J, Li W, Zhongyu Z, Dimitrov D, Scott-Browne JP, Kohler ME, Fry TJ. Rational redesign of antigen binding domain improves in vivo efficacy of the CD22-CAR. Mol Ther. 2026 Apr 01; 34(4):2175-2188.
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Ho AWS, Fukuzawa T, Koga H, Ohmine K, Kawauchi H, Muraoka M, Ikuta Y, Gupta G, Okuda M, Onami I, Ayabe M, Takeiri A, Konishi H, Sugawara Y, Usami S, Ito E, Shibahara N, Ozeki K, Wada Y, Hirako A, Takahashi N, Sampei Z, Haraya K, Murao N, Fujii T, Torizawa T, Shimada H, Igawa T. Long lasting complement neutralisation by RAY121, an engineered anti-C1s antibody with C1q displacement function. EBioMedicine. 2025 Dec; 122:106009.
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Archuleta SR, Miller RC, Mirita JA, Goodrich JA, Kugel JF. Single-molecule Microscopy Reveals That TFIIE Subunits Dynamically Interact With Preinitiation Complexes in a Manner Impacted by TFIIH. J Mol Biol. 2025 Dec 15; 437(24):169528.
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Bekkering ET, Yoo R, Hailemariam S, Heide F, Ivanochko D, Jackman M, Proellochs NI, Stoter R, van Gemert GJ, Maeda A, Yuguchi T, Wanders OT, van Daalen RC, Inklaar MR, Andrade CM, Jansen PWTC, Vermeulen M, Bousema T, Takashima E, Rubinstein JL, Kooij TWA, Jore MM, Julien JP. Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity. 2025 Nov 11; 58(11):2899-2916.e10.
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