 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.679 G03.808
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 9 | 9 | | 1996 | 0 | 17 | 17 | | 1997 | 1 | 15 | 16 | | 1998 | 0 | 21 | 21 | | 1999 | 0 | 13 | 13 | | 2000 | 0 | 29 | 29 | | 2001 | 0 | 39 | 39 | | 2002 | 0 | 52 | 52 | | 2003 | 0 | 38 | 38 | | 2004 | 1 | 47 | 48 | | 2005 | 0 | 64 | 64 | | 2006 | 0 | 65 | 65 | | 2007 | 0 | 55 | 55 | | 2008 | 1 | 60 | 61 | | 2009 | 0 | 64 | 64 | | 2010 | 0 | 68 | 68 | | 2011 | 1 | 88 | 89 | | 2012 | 0 | 90 | 90 | | 2013 | 2 | 82 | 84 | | 2014 | 0 | 71 | 71 | | 2015 | 2 | 63 | 65 | | 2016 | 0 | 90 | 90 | | 2017 | 0 | 77 | 77 | | 2018 | 3 | 69 | 72 | | 2019 | 0 | 67 | 67 | | 2020 | 0 | 73 | 73 | | 2021 | 2 | 41 | 43 | | 2022 | 0 | 21 | 21 | | 2023 | 0 | 17 | 17 | | 2024 | 10 | 36 | 46 | | 2025 | 0 | 40 | 40 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Paukovich N, Spear EA, MacFadden A, Nowling NN, Henen MA, Vögeli B, Filbin ME. Intrinsically disordered cytoplasmic tail in netrin receptor DCC binds the large ribosomal subunit to inhibit translation. J Biol Chem. 2025 Nov; 301(11):110741.
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Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158.
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Saeb D, Lietzke EE, Fuchs DI, Aldrich EC, Bruce KD, Sprenger KG. The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids. Elife. 2025 Sep 10; 13.
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Alemany K, Johnson S, Moore JK. Kinesin-8/Kip3 requires beta tubulin tail for depolymerase activity. J Cell Biol. 2025 Oct 06; 224(10).
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Squiers GT, Wan C, Gorder J, Puscher H, Shen J. A Commander-independent function of COMMD3 in endosomal trafficking. Elife. 2025 Aug 21; 14.
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Kumar A, Sakuraba S, Gaurav N, Selvam K, Kutateladze TG, Kono H. Mechanistic Insights into HP1a CSD Oligomerization and the Role of PxVxL Motif-Containing Proteins. J Chem Inf Model. 2025 Aug 25; 65(16):8768-8780.
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Pratt J, McCann K, Kuo J, Parker R. Polyserine-tau interactions modulate tau fibrillization. J Biol Chem. 2025 Sep; 301(9):110523.
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Chan YS, Gao Q, Robinson SA, Wang W, Filandrova R, Weinhold LM, Cabrera ML, Zhang M, Ambati CSR, Lerario AM, Putluri N, Kiseljak-Vassiliades K, Wierman ME, Habra MA, Hammer GD, Veverka V, Cermakova K, Hodges HC. ß-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
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Gordon BH, Ogunkunle VS, Silvers R. Noncanonical RNA binding of human La-related protein 6. Nucleic Acids Res. 2025 Jul 19; 53(14).
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Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Barget AJ, Whiteley AM, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM. Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology. Sci Adv. 2025 Jul 18; 11(29):eadu6354.
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