 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.679 G03.808
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 17 | 17 | | 1997 | 1 | 17 | 18 | | 1998 | 0 | 21 | 21 | | 1999 | 0 | 13 | 13 | | 2000 | 0 | 30 | 30 | | 2001 | 0 | 39 | 39 | | 2002 | 0 | 51 | 51 | | 2003 | 0 | 38 | 38 | | 2004 | 1 | 45 | 46 | | 2005 | 0 | 67 | 67 | | 2006 | 0 | 65 | 65 | | 2007 | 0 | 53 | 53 | | 2008 | 1 | 62 | 63 | | 2009 | 0 | 64 | 64 | | 2010 | 0 | 68 | 68 | | 2011 | 1 | 92 | 93 | | 2012 | 0 | 91 | 91 | | 2013 | 2 | 86 | 88 | | 2014 | 0 | 72 | 72 | | 2015 | 2 | 65 | 67 | | 2016 | 0 | 94 | 94 | | 2017 | 0 | 78 | 78 | | 2018 | 3 | 76 | 79 | | 2019 | 0 | 66 | 66 | | 2020 | 0 | 74 | 74 | | 2021 | 2 | 41 | 43 | | 2022 | 0 | 21 | 21 | | 2023 | 0 | 17 | 17 | | 2024 | 10 | 38 | 48 | | 2025 | 0 | 49 | 49 | | 2026 | 0 | 12 | 12 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Kroft CW, Krall JB, Warchol M, Welty R, Herbert A, Henen MA, Vögeli B. Za and Zß domains of ADAR1 and ZBP1 bind G-quadruplexes with nanomolar affinities, establishing Zß as a G-quadruplex-specific domain. Nucleic Acids Res. 2026 Apr 23; 54(8).
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Stein CS, Zhang X, Witmer NH, Pennington ER, Hahn S, Straub AC, Shaikh SR, Boudreau RL. Mitoregulin supports mitochondrial membrane integrity and protects against cardiac ischaemia-reperfusion injury. Cardiovasc Res. 2026 Mar 26; 122(3):379-396.
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Dai Y, Brouillard J, Jaycox JR, Yeon SM, Huck JD, Yandamuri SS, Zhong Z, O'Connor KC, Burnina I, Henkel C, LeMay AK, Lilov A, McGurk E, Morrill M, Parker L, Sackett T, Sandberg C, Sivasubramanian A, Geoghegan JC, Ring AM. Off-target reactivity in clinical monoclonal antibodies. Structure. 2026 May 07; 34(5):747-757.e5.
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Ginsberg AG, Ahnström J, Crawley JTB, Leiderman K, Monroe DM, Neeves KB, Sindi SF, Fogelson AL. Mechanisms of thrombin inhibition by protein S and the TFPIa-fVshort-protein S complex. Biophys J. 2026 Apr 07; 125(7):1820-1839.
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Shao C, Indeglia A, Foster M, Casey K, Leung J, Modarai SR, Leu JI, Duong B, Mes-Masson AM, Sims-Mourtada J, Auslander N, Drapkin R, Bitler BG, Zhang N, Murphy ME. Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer. Genes Dev. 2026 02 02; 40(3-4):199-214.
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Zhang J, Bai X, Dai S, Chen Z. Structural study of Nicotiana benthamiana NADPH-dependent thioredoxin reductase C and its molecular mechanism of interaction with 2-Cys peroxiredoxin. Acta Crystallogr D Struct Biol. 2026 Feb 01; 82(Pt 2):126-139.
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Bhattacharya M, Spencer BL, Kwiecinski JM, Podkowik M, Putzel G, Pironti A, Shopsin B, Doran KS, Horswill AR. Collagen binding adhesin restricts Staphylococcus aureus skin infection. Nat Commun. 2026 01 23; 17(1).
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Biswas S, Tavaf Z, Benz C, Khalil M, Becht DC, Simonetti L, Blanco MA, Affar EB, Ivarsson Y, Kutateladze TG. A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3. J Biol Chem. 2026 Mar; 302(3):111189.
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Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Gaurav N, Qin W, Selvam K, Zhou Z, Liu J, Yin Y, Singh RK, O'Hara RA, Tavaf Z, Kumar A, Kono H, Narlikar GJ, Banaszynski LA, Leonhardt H, Kutateladze TG. HP1? self-assembles and cooperates with KAP1 in repression of long noncoding RNA AI662270 in ESCs. Cell Rep. 2026 Feb 24; 45(2):116874.
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