 Oxidative Stress
"Oxidative Stress" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).
| Descriptor ID |
D018384
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| MeSH Number(s) |
G03.673 G07.775.750
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| Concept/Terms |
Oxidative Stress- Oxidative Stress
- Oxidative Stresses
- Stresses, Oxidative
- Stress, Oxidative
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Below are MeSH descriptors whose meaning is more general than "Oxidative Stress".
Below are MeSH descriptors whose meaning is more specific than "Oxidative Stress".
This graph shows the total number of publications written about "Oxidative Stress" by people in this website by year, and whether "Oxidative Stress" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 5 | 6 | | 1997 | 1 | 2 | 3 | | 1998 | 0 | 5 | 5 | | 1999 | 3 | 3 | 6 | | 2000 | 0 | 3 | 3 | | 2001 | 4 | 5 | 9 | | 2002 | 8 | 11 | 19 | | 2003 | 13 | 10 | 23 | | 2004 | 11 | 15 | 26 | | 2005 | 9 | 16 | 25 | | 2006 | 15 | 9 | 24 | | 2007 | 14 | 11 | 25 | | 2008 | 14 | 19 | 33 | | 2009 | 18 | 25 | 43 | | 2010 | 13 | 20 | 33 | | 2011 | 17 | 31 | 48 | | 2012 | 24 | 29 | 53 | | 2013 | 26 | 25 | 51 | | 2014 | 9 | 36 | 45 | | 2015 | 6 | 21 | 27 | | 2016 | 18 | 22 | 40 | | 2017 | 13 | 15 | 28 | | 2018 | 8 | 21 | 29 | | 2019 | 17 | 20 | 37 | | 2020 | 16 | 23 | 39 | | 2021 | 13 | 17 | 30 | | 2022 | 6 | 15 | 21 | | 2023 | 2 | 11 | 13 | | 2024 | 9 | 17 | 26 | | 2025 | 10 | 25 | 35 | | 2026 | 2 | 7 | 9 |
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Below are the most recent publications written about "Oxidative Stress" by people in Profiles.
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Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS. Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12. Aging Cell. 2026 05; 25(5):e70500.
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Darrah MA, Mahoney SA, Venkatasubramanian R, VanDongen NS, Ludwig KR, Seals DR, Rossman MJ, Clayton ZS. Fisetin Supplementation Attenuates Premature Vascular Aging Induced by Doxorubicin via Suppression of Cellular Senescence and Mitochondrial Oxidative Stress. Aging Cell. 2026 May; 25(5):e70535.
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Parween S, Saviola AJ, Howell AC, Varghese S, Galindo DC, Vergara MN. Human retinal organoid model of disease-relevant photoreceptor cell death amenable to drug screening. Cell Death Dis. 2026 Apr 13; 17(1).
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Nguyen BL, Kehmeier MN, Babcock MC, DuBose LE, Hildreth KL, Stauffer BL, Rosenberry R, Keller AC, Steinke K, Miles K, Guerrero L, Kohrt WM, Reusch J, Clayton ZS, Moreau KL. Endothelial Sirtuins and Mitochondrial Function Are Associated With Testosterone Status: Implications for Accelerated Vascular Aging in Middle-Age and Older Men With Low Testosterone. Aging Cell. 2026 04; 25(4):e70457.
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Day BJ. Antioxidants in lung disease: Failures and pathways for success. Free Radic Biol Med. 2026 Jul; 250:216-223.
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Schiavon A, Evaristo C, Saba L, Petiti J, Pignochino Y, Puglisi S, Perotti P, Messina E, Giachino C, Terzolo M, Lo Iacono M. Targeting ER stress in adrenocortical carcinoma: Celastrol as a novel therapeutic candidate. Biomed Pharmacother. 2026 Apr; 197:119156.
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Murray KO, Gioscia-Ryan RA, Justice JN, Santos-Parker JR, Bispham NZ, Hutton DA, Darvish S, Miyamoto-Ditmon J, Clayton ZS, Chonchol M, Seals DR, Rossman MJ. Translational studies of chronic supplementation with a mitochondria-targeted antioxidant to improve physical function with ageing. J Physiol. 2026 04; 604(7):2898-2922.
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Gu W, Ren Z, Gao J, Shen Z, Wang Y, Xu L, Qian R, Miao Q, Wu Y, Hu X, Wu Y, Liu W, Wan CC, Sun L, Cai Y, Sang M, Zheng C, Yan T. Inhibiting NAT10 suppresses hepatocellular carcinoma progression by reducing Nrf2 mRNA stability and increasing oxidative stress. Chem Biol Interact. 2026 Apr 25; 429:111972.
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Ghosh S, Devereaux MW, Anderson AL, Anderson CC, D'Alessandro A, Orlicky DJ, Sokol RJ. Dietary Lauric Acid Suppresses Inflammation, Cholestasis, Hepatocyte Injury, and Senescence in 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-induced Inflammatory Cholangiopathy. Cell Mol Gastroenterol Hepatol. 2026; 20(5):101731.
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Callahan RC, Curry JC, Bhagavatula G, Staley AW, Schaefer RE, Minhajuddin F, Zhou L, Neuhart RM, Atif SM, Orlicky DJ, Cartwright IM, Gerich ME, Steiner CA, Theiss AL, Hall CH, Colgan SP, Onyiah JC. Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner. JCI Insight. 2026 Feb 09; 11(3).
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