 HIV-1
"HIV-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte.
| Descriptor ID |
D015497
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| MeSH Number(s) |
B04.820.650.589.650.350.400
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| Concept/Terms |
HIV-1- HIV-1
- Human immunodeficiency virus 1
- HIV-I
- Immunodeficiency Virus Type 1, Human
- Human Immunodeficiency Virus Type 1
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Below are MeSH descriptors whose meaning is more general than "HIV-1".
Below are MeSH descriptors whose meaning is more specific than "HIV-1".
This graph shows the total number of publications written about "HIV-1" by people in this website by year, and whether "HIV-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 11 | 5 | 16 | | 1996 | 9 | 4 | 13 | | 1997 | 5 | 1 | 6 | | 1998 | 12 | 2 | 14 | | 1999 | 10 | 0 | 10 | | 2000 | 13 | 4 | 17 | | 2001 | 8 | 3 | 11 | | 2002 | 11 | 4 | 15 | | 2003 | 8 | 3 | 11 | | 2004 | 12 | 8 | 20 | | 2005 | 10 | 7 | 17 | | 2006 | 17 | 0 | 17 | | 2007 | 10 | 3 | 13 | | 2008 | 13 | 8 | 21 | | 2009 | 9 | 3 | 12 | | 2010 | 20 | 3 | 23 | | 2011 | 23 | 6 | 29 | | 2012 | 19 | 8 | 27 | | 2013 | 17 | 4 | 21 | | 2014 | 30 | 11 | 41 | | 2015 | 17 | 7 | 24 | | 2016 | 20 | 9 | 29 | | 2017 | 14 | 12 | 26 | | 2018 | 16 | 7 | 23 | | 2019 | 12 | 5 | 17 | | 2020 | 12 | 8 | 20 | | 2021 | 11 | 6 | 17 | | 2022 | 19 | 1 | 20 | | 2023 | 12 | 0 | 12 | | 2024 | 9 | 4 | 13 | | 2025 | 7 | 1 | 8 |
To return to the timeline, click here.
Below are the most recent publications written about "HIV-1" by people in Profiles.
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Kim S, Radford CE, Xu D, Zhong J, Do J, Pham DM, Travisano KA, Filsinger Interrante MV, Bruun TUJ, Rezek V, Wilder B, Palomares M, Seaman MS, Kitchen SG, Bloom JD, Kim PS. A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning. Nat Commun. 2025 May 18; 16(1):4617.
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Briganti L, Annamalai AS, Bester SM, Wei G, Andino-Moncada JR, Singh SP, Kleinpeter AB, Tripathi M, Nguyen B, Radhakrishnan R, Singh PK, Greenwood J, Schope LI, Haney R, Huang S-W, Freed EO, Engelman AN, Francis AC, Kvaratskhelia M. Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir. mBio. 2025 May 14; 16(5):e0361324.
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Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin A, Johnston NM, Bruun TUJ, Utz A, Ghanim HY, Lesch BJ, McLaughlin TM, Dudek AM, Porteus MH. Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies. Nat Commun. 2025 Apr 01; 16(1):3103.
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Cunningham CK, McFarland EJ, Muresan P, Capparelli EV, Perlowski C, Johnston B, Bone F, Purdue L, Yin DE, Moye J, Spiegel HML, Majji S, Theron GB, Mujuru HA, Purswani M, Alvarez G, Deville JG, Chambers C, Brown E, Harding PA, Tobin NH, Low K, Gama L. Safety, Tolerability, and Pharmacokinetics of Long-Acting Broadly Neutralizing HIV-1 Monoclonal Antibody VRC07-523LS in Newborn Infants Exposed to HIV-1. J Pediatric Infect Dis Soc. 2025 Feb 06; 14(2).
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Huang SW, Briganti L, Annamalai AS, Greenwood J, Shkriabai N, Haney R, Armstrong ML, Wempe MF, Singh SP, Francis AC, Engelman AN, Kvaratskhelia M. The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir. PLoS Pathog. 2025 Jan; 21(1):e1012862.
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Li J, Patel SK, Sweeney Y, Patton D, Anderson P, Hillier SL, Rohan LC. Engineering vaginal film platform for mucoadhesion and sustained drug release for HIV-1 prevention. J Control Release. 2025 Mar 10; 379:696-707.
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Flick H, Venbakkam A, Singh PK, Layish B, Huang S-W, Radhakrishnan R, Kvaratskhelia M, Engelman AN, Kane M. Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins. mBio. 2025 Mar 12; 16(3):e0264624.
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Patel M, Panja S, Zaman LA, Yeapuri P, Bhattarai S, Gorantla S, Chang L, Heredia A, Walczak P, Hanson B, Cohen SM, Kevadiya BD, Gendelman HE. CCR5-ligand decorated rilpivirine lipid-based nanoparticles for sustained antiretroviral responses. Nat Commun. 2025 Jan 08; 16(1):513.
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Nicholson LK, Kofonow JM, Robertson CE, Wright T, Li Q, Gardner EM, Frank DN, Janoff EN. Clinical and Microbial Determinants of Upper Respiratory Colonization With Streptococcus pneumoniae and Native Microbiota in People With Human Immunodeficiency Virus Type 1 and Control Adults. J Infect Dis. 2024 Dec 16; 230(6):1456-1465.
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Dinh T, Tber Z, Rey JS, Mengshetti S, Annamalai AS, Haney R, Briganti L, Amblard F, Fuchs JR, Cherepanov P, Kim K, Schinazi RF, Perilla JR, Kim B, Kvaratskhelia M. The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. mBio. 2024 Nov 13; 15(11):e0046524.
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