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																		 Genetic Engineering
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Genetic Engineering" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.
    
			 
				
				
					
						| Descriptor ID | D005818 |  
						| MeSH Number(s) | E05.393.420 |  
						| Concept/Terms | Genetic EngineeringGenetic EngineeringGenetic InterventionIntervention, GeneticGenetic InterventionsInterventions, GeneticEngineering, Genetic
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				Below are MeSH descriptors whose meaning is more general than "Genetic Engineering". 
				Below are MeSH descriptors whose meaning is more specific than "Genetic Engineering". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Genetic Engineering" by people in this website by year, and whether "Genetic Engineering" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1996 | 1 | 1 | 2 |  | 2000 | 0 | 4 | 4 |  | 2002 | 1 | 3 | 4 |  | 2003 | 2 | 3 | 5 |  | 2004 | 1 | 3 | 4 |  | 2005 | 0 | 1 | 1 |  | 2006 | 1 | 0 | 1 |  | 2007 | 1 | 0 | 1 |  | 2008 | 0 | 2 | 2 |  | 2009 | 2 | 2 | 4 |  | 2010 | 1 | 3 | 4 |  | 2011 | 2 | 0 | 2 |  | 2012 | 1 | 0 | 1 |  | 2013 | 3 | 3 | 6 |  | 2014 | 3 | 1 | 4 |  | 2015 | 2 | 3 | 5 |  | 2016 | 2 | 3 | 5 |  | 2017 | 1 | 1 | 2 |  | 2018 | 1 | 1 | 2 |  | 2019 | 4 | 3 | 7 |  | 2020 | 4 | 0 | 4 |  | 2021 | 1 | 2 | 3 |  | 2024 | 0 | 1 | 1 |  | 2025 | 0 | 1 | 1 | 
 
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				Below are the most recent publications written about "Genetic Engineering" by people in Profiles. 		
					
								
								Wilkes RA, Miller TE, Waldbauer J, Zhou N, Zhang L, DiBiase BN, Kamat NP, Aristilde L, Beckham GT, Werner AZ. Engineered Membrane Vesicle Production via oprF or oprI Deletion Has Distinct Phenotypic Effects in Pseudomonas putida. ACS Synth Biol. 2025 Jul 18; 14(7):2739-2752.
								Saunders SH, Ahmed AM. ORBIT for E. coli: kilobase-scale oligonucleotide recombineering at high throughput and high efficiency. Nucleic Acids Res. 2024 May 08; 52(8):e43.
								Fernbach J, Meile S, Kilcher S, Loessner MJ. Genetic Engineering and Rebooting of Bacteriophages in L-Form Bacteria. Methods Mol Biol. 2024; 2734:247-259.
								Kent A, Longino NV, Christians A, Davila E. Naturally Occurring Genetic Alterations in Proximal TCR Signaling and Implications for Cancer Immunotherapy. Front Immunol. 2021; 12:658611.
								Powers JM, Haese NN, Denton M, Ando T, Kreklywich C, Bonin K, Streblow CE, Kreklywich N, Smith P, Broeckel R, DeFilippis V, Morrison TE, Heise MT, Streblow DN. Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses. PLoS Negl Trop Dis. 2021 04; 15(4):e0009308.
								Rabinowitch I, Upadhyaya B, Pant A, Galski D, Kreines L, Bai J. Circumventing neural damage in a C.?elegans chemosensory circuit using genetically engineered synapses. Cell Syst. 2021 03 17; 12(3):263-271.e4.
								Brempelis KJ, Cowan CM, Kreuser SA, Labadie KP, Prieskorn BM, Lieberman NAP, Ene CI, Moyes KW, Chinn H, DeGolier KR, Matsumoto LR, Daniel SK, Yokoyama JK, Davis AD, Hoglund VJ, Smythe KS, Balcaitis SD, Jensen MC, Ellenbogen RG, Campbell JS, Pierce RH, Holland EC, Pillarisetty VG, Crane CA. Genetically engineered macrophages persist in solid tumors and locally deliver therapeutic proteins to activate immune responses. J Immunother Cancer. 2020 10; 8(2).
								Meile S, Kilcher S, Loessner MJ, Dunne M. Reporter Phage-Based Detection of Bacterial Pathogens: Design Guidelines and Recent Developments. Viruses. 2020 08 26; 12(9).
								Chatterjee A, Cerna Sanchez JA, Yamauchi T, Taupin V, Couvrette J, Gorodetsky AA. Cephalopod-inspired optical engineering of human cells. Nat Commun. 2020 06 02; 11(1):2708.
								Choudhury A, Fenster JA, Fankhauser RG, Kaar JL, Tenaillon O, Gill RT. CRISPR/Cas9 recombineering-mediated deep mutational scanning of essential genes in Escherichia coli. Mol Syst Biol. 2020 Mar; 16(3):e9265. | 
																	
																		
																			
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