 Extracellular Signal-Regulated MAP Kinases
"Extracellular Signal-Regulated MAP Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
| Descriptor ID |
D048049
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249 D12.644.360.450.169 D12.776.476.450.169
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| Concept/Terms |
Extracellular Signal-Regulated MAP Kinases- Extracellular Signal-Regulated MAP Kinases
- Extracellular Signal Regulated MAP Kinases
- MAP Kinases, Extracellular Signal-Regulated
- MAP Kinases, Extracellular Signal Regulated
- ERK MAP Kinases
- Extracellular Signal-Regulated Kinases
- Extracellular Signal Regulated Kinases
- Kinases, Extracellular Signal-Regulated
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Below are MeSH descriptors whose meaning is more general than "Extracellular Signal-Regulated MAP Kinases".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Signal-Regulated MAP Kinases".
This graph shows the total number of publications written about "Extracellular Signal-Regulated MAP Kinases" by people in this website by year, and whether "Extracellular Signal-Regulated MAP Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 1 | 1 | 2 | | 2005 | 3 | 2 | 5 | | 2006 | 3 | 8 | 11 | | 2007 | 0 | 8 | 8 | | 2008 | 2 | 8 | 10 | | 2009 | 1 | 7 | 8 | | 2010 | 3 | 5 | 8 | | 2011 | 3 | 3 | 6 | | 2012 | 1 | 5 | 6 | | 2013 | 2 | 4 | 6 | | 2014 | 1 | 8 | 9 | | 2015 | 2 | 4 | 6 | | 2016 | 1 | 5 | 6 | | 2017 | 3 | 1 | 4 | | 2018 | 0 | 1 | 1 | | 2019 | 3 | 2 | 5 | | 2020 | 2 | 4 | 6 | | 2021 | 1 | 2 | 3 | | 2023 | 0 | 1 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Extracellular Signal-Regulated MAP Kinases" by people in Profiles.
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Hoffman TE, Tian C, Nangia V, Yang C, Regot S, Gerosa L, Spencer SL. CDK2 activity crosstalk on the ERK kinase translocation reporter can be resolved computationally. Cell Syst. 2025 Jan 15; 16(1):101162.
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Chen JY, Hug C, Reyes J, Tian C, Gerosa L, Fr?hlich F, Ponsioen B, Snippert HJG, Spencer SL, Jambhekar A, Sorger PK, Lahav G. Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction. Cell Rep. 2023 03 28; 42(3):112252.
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Peron M, Dinarello A, Meneghetti G, Martorano L, Betto RM, Facchinello N, Tesoriere A, Tiso N, Martello G, Argenton F. Y705 and S727 are required for the mitochondrial import and transcriptional activities of STAT3, and for regulation of stem cell proliferation. Development. 2021 09 01; 148(17).
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Anson KJ, Corbet GA, Palmer AE. Zn2+ influx activates ERK and Akt signaling pathways. Proc Natl Acad Sci U S A. 2021 03 16; 118(11).
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Sripada A, Sirohi K, Michalec L, Guo L, McKay JT, Yadav S, Verma M, Good J, Rollins D, Gorska MM, Alam R. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021 03; 19(3):e3001063.
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Brown CN, Atwood D, Pokhrel D, Holditch SJ, Altmann C, Skrypnyk NI, Bourne J, Klawitter J, Blaine J, Faubel S, Thorburn A, Edelstein CL. Surgical procedures suppress autophagic flux in the kidney. Cell Death Dis. 2021 03 05; 12(3):248.
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Ma H, Han F, Yan X, Qi G, Li Y, Li R, Yan S, Yuan C, Song K, Kong B. PBK promotes aggressive phenotypes of cervical cancer through ERK/c-Myc signaling pathway. J Cell Physiol. 2021 04; 236(4):2767-2781.
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Lucas ED, Schafer JB, Matsuda J, Kraus M, Burchill MA, Tamburini BAJ. PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity. Cell Rep. 2020 10 13; 33(2):108258.
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Cowan JR, Salyer L, Wright NT, Kinnamon DD, Amaya P, Jordan E, Bamshad MJ, Nickerson DA, Hershberger RE. SOS1 Gain-of-Function Variants in Dilated Cardiomyopathy. Circ Genom Precis Med. 2020 08; 13(4):e002892.
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Wang Q, Notay K, Downey GP, McCulloch CA. The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation. Cell Rep. 2020 06 30; 31(13):107781.
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