 Troponin I
"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
| Descriptor ID |
D019210
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| MeSH Number(s) |
D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Troponin I".
Below are MeSH descriptors whose meaning is more specific than "Troponin I".
This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2006 | 2 | 0 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 2 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 5 | 1 | 6 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 3 | 4 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 3 | 4 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 1 | 3 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Troponin I" by people in Profiles.
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Huebschmann AG, Wenger NK, Bairey Merz CN, Jaffe AS, Allen LA, Trent SA, Regensteiner JG. Potential for Misapplication of a Uniform vs Sex-Specific High-Sensitivity Cardiac Troponin Threshold. J Am Coll Cardiol. 2024 Sep 10; 84(11):e83-e84.
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Lynch DR, Sharma S, Hearle P, Greeley N, Gunther K, Keita M, Strawser C, Hauser L, Park C, Schadt K, Lin KY. Characterization of clinical serum cardiac biomarker levels in individuals with Friedreich ataxia. J Neurol Sci. 2024 Jun 15; 461:123053.
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Salyer LG, Salhi HE, Brundage EA, Shettigar V, Sturgill SL, Zanella H, Templeton B, Abay E, Emmer KM, Lowe J, Rafael-Fortney JA, Parinandi N, Foster DB, McKinsey TA, Woulfe KC, Ziolo MT, Biesiadecki BJ. Troponin I Tyrosine Phosphorylation Beneficially Accelerates Diastolic Function. Circ Res. 2024 01 05; 134(1):33-45.
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Salhi HE, Shettigar V, Salyer L, Sturgill S, Brundage EA, Robinett J, Xu Z, Abay E, Lowe J, Janssen PML, Rafael-Fortney JA, Weisleder N, Ziolo MT, Biesiadecki BJ. The lack of Troponin I Ser-23/24 phosphorylation is detrimental to in vivo cardiac function and exacerbates cardiac disease. J Mol Cell Cardiol. 2023 03; 176:84-96.
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Bonaca MP, Reece TB. The prognostic implications of cardiac troponin in Type A aortic dissection and the challenge of understanding therapeutic consequences. Eur Heart J Acute Cardiovasc Care. 2022 08 09; 11(8):607-608.
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Berg DD, Freedman BL, Bonaca MP, Jarolim P, Scirica BM, Goodrich EL, Sabatine MS, Morrow DA. Cardiovascular Biomarkers and Heart Failure Risk in Stable Patients With Atherothrombotic Disease: A Nested Biomarker Study From TRA 2?P-TIMI 50. J Am Heart Assoc. 2021 05 04; 10(9):e018673.
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Shah AB, Nabhan D, Chapman R, Chiampas G, Drezner J, Olin JT, Taylor D, Finnoff JT, Baggish AL. Resumption of Sport at the United States Olympic and Paralympic Training Facilities During the COVID-19 Pandemic. Sports Health. 2021 Jul-Aug; 13(4):359-363.
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Kavsak PA, Cerasuolo JO, Ko DT, Ma J, Sherbino J, Mondoux SE, Clayton N, Hill SA, McQueen M, Griffith LE, Mehta SR, Perez R, Seow H, Devereaux PJ, Worster A. Using the clinical chemistry score in the emergency department to detect adverse cardiac events: a diagnostic accuracy study. CMAJ Open. 2020 Oct-Dec; 8(4):E676-E684.
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Lee S, Allen AJH, Morley E, Swart P, Henderson W, Jen R, Ayas N. Perioperative myocardial injury risk after elective knee and hip arthroplasty in patients with a high risk of obstructive sleep apnea. Sleep Breath. 2021 Mar; 25(1):513-515.
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Lin YH, Schmidt W, Fritz KS, Jeong MY, Cammarato A, Foster DB, Biesiadecki BJ, McKinsey TA, Woulfe KC. Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity. J Mol Cell Cardiol. 2020 02; 139:135-147.
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