Phenotype
"Phenotype" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.
| Descriptor ID |
D010641
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| MeSH Number(s) |
G05.695
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phenotype".
Below are MeSH descriptors whose meaning is more specific than "Phenotype".
This graph shows the total number of publications written about "Phenotype" by people in this website by year, and whether "Phenotype" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 10 | 10 | | 1996 | 0 | 15 | 15 | | 1997 | 0 | 17 | 17 | | 1998 | 0 | 20 | 20 | | 1999 | 4 | 15 | 19 | | 2000 | 1 | 26 | 27 | | 2001 | 0 | 35 | 35 | | 2002 | 2 | 39 | 41 | | 2003 | 1 | 38 | 39 | | 2004 | 3 | 45 | 48 | | 2005 | 4 | 44 | 48 | | 2006 | 3 | 45 | 48 | | 2007 | 4 | 57 | 61 | | 2008 | 3 | 45 | 48 | | 2009 | 5 | 52 | 57 | | 2010 | 5 | 90 | 95 | | 2011 | 6 | 75 | 81 | | 2012 | 6 | 73 | 79 | | 2013 | 10 | 96 | 106 | | 2014 | 8 | 104 | 112 | | 2015 | 15 | 105 | 120 | | 2016 | 13 | 89 | 102 | | 2017 | 11 | 110 | 121 | | 2018 | 13 | 114 | 127 | | 2019 | 15 | 111 | 126 | | 2020 | 6 | 87 | 93 | | 2021 | 14 | 115 | 129 | | 2022 | 0 | 63 | 63 | | 2023 | 1 | 96 | 97 | | 2024 | 27 | 62 | 89 | | 2025 | 2 | 68 | 70 |
To return to the timeline, click here.
Below are the most recent publications written about "Phenotype" by people in Profiles.
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Tamura S, Nelson AD, Spratt PWE, Hamada EC, Zhou X, Kyoung H, Li Z, Arnould C, Barskyi V, Krupkin B, Young K, Zhao J, Holden SS, Sahagun A, Keeshen CM, Lu C, Ben-Shalom R, Taloma SE, Schamiloglu S, Li YC, Min L, Jenkins PM, Pan JQ, Paz JT, Sanders SJ, Matharu N, Ahituv N, Bender KJ. CRISPR activation for SCN2A-related neurodevelopmental disorders. Nature. 2025 Oct; 646(8086):983-991.
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Mulkearns-Hubert EE, Hajdari N, Hong ES, Jacobs AP, Gaboriau A, Giltner S, Tannish G, Kay KE, Wang SZ, LaViolette PS, Silver DJ, Hubert CG, Dhawan A, Lathia JD. Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis. Cell Rep. 2025 Sep 23; 44(9):116303.
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Krishnan M, Anwar MY, Justice AE, Chittoor G, Chen HH, Roshani R, Scartozzi A, Dickerson RR, Smit RAJ, Preuss MH, Chami N, Hadad BS, Parra EJ, Cruz M, Hui Q, Wilson PWF, Sun YV, Zhang X, Linchangco GV, Kardia SLR, Faul JD, Weir DR, Bielak LF, Highland HM, Young KL, Qi B, Wang Y, Fornage M, Haiman C, Cheng I, Peters U, Kooperberg C, Buyske S, McCormick JB, Fisher-Hoch SP, Lona-Durazo F, Peralta J, Gomez-Zamudio J, Rich SS, Ferrier KR, Lange EM, Gignoux CR, Kenny EE, Wojcik GL, Cho K, Gaziano MJ, Djousse L, Liu S, Vaidya D, de Mutsert R, Josyula NS, Bauer CR, Zhao W, Walker RW, Smith JA, Lange LA, Meyer MC, Liu CT, Yanek LR, Lee M, Raffield LM, Loos RJF, Gordon-Larsen P, Below JE, North KE, Graff M. Genome-wide association study provides novel insight into the genetic architecture of severe obesity. PLoS Genet. 2025 Sep; 21(9):e1011842.
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Lachowiez CA, Heiblig M, Aspas Requena G, Tavernier-Tardy E, Dai F, Ashango AB, Peters DT, Fang J, Kaempf A, Long N, Eide CA, Kurtz SE, Xie W, Agarwal A, Sahasrabudhe A, McMahon CM, Amaya ML, Meyers G, Gandhi A, Leonard J, Hayes-Lattin B, Maziarz RT, Traer E, Cook RJ, Swords R, Braun TP, Saultz JN, Eckel AM, Loken MR, Zeidner JF, Tyner JW, Pollyea DA. Genetic and Phenotypic Correlates of Clinical Outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN Study. Blood Cancer Discov. 2025 Sep 03; 6(5):437-449.
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Boeri S, Piai M, Russo S, Alari V, Cogliati F, Simonetta D, Benke TA, Nobili L, Prato G. Clinical differences in monozygotic twins with Rett syndrome: case report and systematic review. Orphanet J Rare Dis. 2025 Sep 02; 20(1):473.
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Kiernan E, Zelnick LR, Khader A, Coston TD, Bailey ZA, Speckmaier S, Lo JJ, Siew ED, Sathe NA, Kestenbaum BR, Himmelfarb J, Johnson NJ, Shapiro NI, Douglas IS, Hough CL, Bhatraju PK. Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation. Am J Respir Crit Care Med. 2025 Sep; 211(9):1681-1688.
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Mumme-Monheit A, Gustafson GE, Hopkins CA, Bailon-Zambrano R, Sucharov J, Lippincott MJ, Way GP, Colborn KL, Nichols JT. A quadratic paradigm describes the relationship between phenotype severity and variation. Nat Commun. 2025 Sep 01; 16(1):8154.
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Savonitto G, Paldino A, Setti M, Furlan S, Tavcar I, Ribichini FL, Perotto M, Gigli M, Mestroni L, Dal Ferro M, Merlo M, Sinagra G. Prognostic role of exercise intensity in familial Filamin C truncating variants. Open Heart. 2025 Aug 27; 12(2).
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Johnson EC, Lai D, Balbona JV, Miller AP, Hatoum AS, Deak JD, Jennings M, Baranger DAA, Galimberti M, Sanichwankul K, Thorgeirsson T, Colbert SMC, Adhikari K, Docherty AR, Degenhardt L, Edwards T, Fox L, Giannelis A, Jeffries PW, Korhonen T, Morrison CL, Nunez YZ, Palviainen T, Su MH, Romero Villela PN, Wetherill L, Willoughby EA, Zellers SM, Bierut LJ, Buchwald J, Copeland WE, Corley RP, Friedman NP, Foroud TM, Gillespie NA, Gizer IR, Heath AC, Hickie IB, Kaprio J, Keller MC, Lee JJ, Lind P, Madden PA, Maes HHM, Martin NG, McGue M, Medland SE, Nelson EC, Pearson J, Porjesz B, Stallings MC, Vrieze S, Wilhelmson KC, Kranzler HR, Walters RK, Polimanti R, Malison R, Zhou H, Stefansson K, Sanchez-Roige S, Potenza M, Mutirangura A, Shotelersuk V, Kalayasiri R, Edenberg HJ, Gelernter J, Agrawal A. Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med. 2025 Aug 20; 55:e234.
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Davis SM, Liu A, Teerlink CC, Lapato DM, Gorman B, Genovese G, Singh M, Reeve MP, Gentry AE, Donner KM, Sipilä TP, Ghazal A, Pagadala MS, Panizzon MS, Lancaster EE, Chatzinakos C, Ganna A, Bigdeli TB, Daly MJ, Lynch JA, Ross J, Peterson RE, Hauger RL. Phenome-wide association study of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank. Am J Hum Genet. 2025 Sep 04; 112(9):2088-2101.
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