 3' Untranslated Regions
"3' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 3' end of messenger RNA that does not code for product. This region contains transcription and translation regulating sequences.
| Descriptor ID |
D020413
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| MeSH Number(s) |
D13.444.735.544.875.880 D13.444.735.790.878.880 G05.360.340.024.220.880.880 G05.360.340.024.340.137.910.880
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| Concept/Terms |
3' Untranslated Regions- 3' Untranslated Regions
- 3'UTR
- 3'UTRs
- 3' Untranslated Region
- Region, 3' Untranslated
- Regions, 3' Untranslated
- Untranslated Region, 3'
- Untranslated Regions, 3'
- 3' UTR
- 3' UTRs
- UTR, 3'
- UTRs, 3'
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Below are MeSH descriptors whose meaning is more general than "3' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "3' Untranslated Regions".
This graph shows the total number of publications written about "3' Untranslated Regions" by people in this website by year, and whether "3' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 2 | 2 | 4 | | 2008 | 0 | 5 | 5 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 8 | 8 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 6 | 8 | | 2013 | 2 | 1 | 3 | | 2014 | 3 | 4 | 7 | | 2015 | 0 | 4 | 4 | | 2016 | 0 | 5 | 5 | | 2017 | 1 | 3 | 4 | | 2018 | 2 | 2 | 4 | | 2020 | 0 | 4 | 4 | | 2021 | 3 | 4 | 7 | | 2022 | 0 | 6 | 6 |
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Below are the most recent publications written about "3' Untranslated Regions" by people in Profiles.
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Graham ME, Merrick C, Akiyama BM, Szucs MJ, Leach S, Kieft JS, Beckham JD. Zika virus dumbbell-1 structure is critical for sfRNA presence and cytopathic effect during infection. mBio. 2023 Aug 31; 14(4):e0110823.
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Geisberg JV, Moqtaderi Z, Fong N, Erickson B, Bentley DL, Struhl K. Nucleotide-level linkage of transcriptional elongation and polyadenylation. Elife. 2022 11 24; 11.
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Riella CV, McNulty M, Ribas GT, Tattersfield CF, Perez-Gill C, Eichinger F, Kelly J, Chun J, Subramanian B, Guizelini D, Alper SL, Pollak MR, Sampson MG, Friedman DJ. ADAR regulates APOL1 via A-to-I RNA editing by inhibition of MDA5 activation in a paradoxical biological circuit. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2210150119.
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Arora A, Castro-Gutierrez R, Moffatt C, Eletto D, Becker R, Brown M, Moor AE, Russ HA, Taliaferro JM. High-throughput identification of RNA localization elements in neuronal cells. Nucleic Acids Res. 2022 10 14; 50(18):10626-10642.
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Lee S, Chen YC, Gillen AE, Taliaferro JM, Deplancke B, Li H, Lai EC. Diverse cell-specific patterns of alternative polyadenylation in Drosophila. Nat Commun. 2022 09 13; 13(1):5372.
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Freeman CL, Pararajalingam P, Jin L, Balasubramanian S, Jiang A, Xu W, Grau M, Zapukhlyak M, Boyle M, Hodkinson B, Schaffer M, Enny C, Deshpande S, Sun S, Vermeulen J, Morin RD, Scott DW, Lenz G. Molecular determinants of outcomes in relapsed or refractory mantle cell lymphoma treated with ibrutinib or temsirolimus in the MCL3001 (RAY) trial. Leukemia. 2022 10; 36(10):2479-2487.
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Tseng V, Collum SD, Allawzi A, Crotty K, Yeligar S, Trammell A, Ryan Smith M, Kang BY, Sutliff RL, Ingram JL, Jyothula SSSK, Thandavarayan RA, Huang HJ, Nozik ES, Wagner EJ, Michael Hart C, Karmouty-Quintana H. 3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension. Matrix Biol. 2022 08; 111:53-75.
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Bilodeau DY, Sheridan RM, Balan B, Jex AR, Rissland OS. Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia. RNA. 2022 05; 28(5):668-682.
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Siegel DA, Le Tonqueze O, Biton A, Zaitlen N, Erle DJ. Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration predict mRNA destabilization. G3 (Bethesda). 2022 01 04; 12(1).
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Li Y, Li J, Wang J, Lynch DR, Shen X, Corey DR, Parekh D, Bhat B, Woo C, Cherry JJ, Napierala JS, Napierala M. Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression. Nucleic Acids Res. 2021 11 18; 49(20):11560-11574.
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