 Drug Evaluation, Preclinical
"Drug Evaluation, Preclinical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Preclinical testing of drugs in experimental animals or in vitro for their biological and toxic effects and potential clinical applications.
| Descriptor ID |
D004353
|
| MeSH Number(s) |
E05.295.750 E05.337.550
|
| Concept/Terms |
Drug Evaluation, Preclinical- Drug Evaluation, Preclinical
- Drug Evaluations, Preclinical
- Drug Screening
- Drug Screenings
- Screening, Drug
- Screenings, Drug
- Evaluation Studies, Drug, Pre-Clinical
- Preclinical Drug Evaluations
- Evaluation, Preclinical Drug
- Evaluations, Preclinical Drug
- Preclinical Drug Evaluation
- Drug Evaluation Studies, Preclinical
- Evaluation Studies, Drug, Preclinical
|
Below are MeSH descriptors whose meaning is more general than "Drug Evaluation, Preclinical".
Below are MeSH descriptors whose meaning is more specific than "Drug Evaluation, Preclinical".
This graph shows the total number of publications written about "Drug Evaluation, Preclinical" by people in this website by year, and whether "Drug Evaluation, Preclinical" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 | | 1997 | 1 | 3 | 4 | | 1999 | 0 | 2 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 2 | 7 | 9 | | 2003 | 1 | 3 | 4 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 3 | 4 | | 2008 | 1 | 5 | 6 | | 2009 | 1 | 5 | 6 | | 2010 | 0 | 11 | 11 | | 2011 | 1 | 7 | 8 | | 2012 | 2 | 7 | 9 | | 2013 | 1 | 8 | 9 | | 2014 | 2 | 6 | 8 | | 2015 | 1 | 8 | 9 | | 2016 | 0 | 3 | 3 | | 2017 | 2 | 9 | 11 | | 2018 | 2 | 4 | 6 | | 2019 | 3 | 4 | 7 | | 2020 | 0 | 8 | 8 | | 2021 | 4 | 6 | 10 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 3 | 3 | | 2025 | 0 | 1 | 1 | | 2026 | 0 | 3 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Drug Evaluation, Preclinical" by people in Profiles.
-
Parween S, Saviola AJ, Howell AC, Varghese S, Galindo DC, Vergara MN. Human retinal organoid model of disease-relevant photoreceptor cell death amenable to drug screening. Cell Death Dis. 2026 Apr 13; 17(1).
-
Meena S, Fatima F, Qais FA, Ramachandran S. Computational screening of natural plant and marine compounds as potential inhibitors of Mycobacterium tuberculosis dihydrodipicolinate synthase. Comput Biol Chem. 2026 Jun; 122:108936.
-
Singh S, Boorgula GD, Nguyen MH, Daley CL, Gumbo T, Srivastava S. Preclinical evaluation of epetraborole in the hollow fibre system model of Mycobacterium abscessus lung disease. J Antimicrob Chemother. 2026 Jan 06; 81(1).
-
Gracey EG, Lampe JN. Novel emerging cell and organoid systems for the study of drug metabolism and toxicity in humans. Drug Metab Dispos. 2025 Dec; 53(12):100188.
-
Tengesdal IW, Banks M, Dinarello CA, Marchetti C. Screening NLRP3 drug candidates in clinical development: lessons from existing and emerging technologies. Front Immunol. 2024; 15:1422249.
-
Dartois V, Bonfield TL, Boyce JP, Daley CL, Dick T, Gonzalez-Juarrero M, Gupta S, Kramnik I, Lamichhane G, Laughon BE, Lorè NI, Malcolm KC, Olivier KN, Tuggle KL, Jackson M. Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations. Tuberculosis (Edinb). 2024 07; 147:102503.
-
Karuppasamy M, English KG, Henry CA, Manzini MC, Parant JM, Wright MA, Ruparelia AA, Currie PD, Gupta VA, Dowling JJ, Maves L, Alexander MS. Standardization of zebrafish drug testing parameters for muscle diseases. Dis Model Mech. 2024 01 01; 17(1).
-
Griffin KH, Thorpe SW, Sebastian A, Hum NR, Coonan TP, Sagheb IS, Loots GG, Randall RL, Leach JK. Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening. Proc Natl Acad Sci U S A. 2023 09 26; 120(39):e2302101120.
-
Tebon PJ, Wang B, Markowitz AL, Davarifar A, Tsai BL, Krawczuk P, Gonzalez AE, Sartini S, Murray GF, Nguyen HTL, Tavanaie N, Nguyen TL, Boutros PC, Teitell MA, Soragni A. Drug screening at single-organoid resolution via bioprinting and interferometry. Nat Commun. 2023 06 06; 14(1):3168.
-
Rudolph J, Jung K, Luger K. Inhibitors of PARP: Number crunching and structure gazing. Proc Natl Acad Sci U S A. 2022 03 15; 119(11):e2121979119.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|