 Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.775.100 D12.776.467.374.687.100 D12.776.467.942.775.100 D23.529.374.687.100 D23.529.942.775.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 3 | 3 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 6 | 6 | | 2004 | 0 | 4 | 4 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 6 | 6 | | 2007 | 3 | 2 | 5 | | 2008 | 3 | 1 | 4 | | 2009 | 1 | 5 | 6 | | 2010 | 4 | 1 | 5 | | 2011 | 1 | 3 | 4 | | 2012 | 3 | 3 | 6 | | 2013 | 3 | 3 | 6 | | 2014 | 2 | 6 | 8 | | 2015 | 2 | 2 | 4 | | 2016 | 2 | 3 | 5 | | 2017 | 2 | 2 | 4 | | 2018 | 1 | 1 | 2 | | 2019 | 3 | 2 | 5 | | 2020 | 4 | 5 | 9 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 3 | 3 | | 2023 | 1 | 1 | 2 | | 2024 | 1 | 1 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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Kines KT, Fairchild HR, Elder AM, Cozzens LM, Strugar ZP, Wessells VM, Becks AR, Porter WW, Borges VF, Lyons TR. Aging-induced semaphorin 7a promotes TGF-ß1-mediated cell plasticity and breast tumor metastases. Cell Rep. 2025 Aug 26; 44(8):116042.
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Faust HJ, Cheng TY, Korsunsky I, Watts GFM, Gal-Oz ST, Trim WV, Kongthong S, Jonsson AH, Simmons DP, Zhang F, Padera R, Chubinskaya S, Wei K, Raychaudhuri S, Lynch L, Moody DB, Brenner MB. Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. Nat Commun. 2024 11 14; 15(1):9859.
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Roeder F, Röpke T, Steinmetz LK, Kolb M, Maus UA, Smith BJ, Knudsen L. Exploring alveolar recruitability using positive end-expiratory pressure in mice overexpressing TGF-ß1: a structure-function analysis. Sci Rep. 2024 04 06; 14(1):8080.
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Jolly AJ, Lu S, Dubner AM, Strand KA, Mutryn MF, Pilotti-Riley A, Danis EP, Nemenoff RA, Moulton KS, Majesky MW, Weiser-Evans MC. Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis. JCI Insight. 2023 05 08; 8(9).
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Geiger F, Zeitlmayr S, Staab-Weijnitz CA, Rajan S, Breit A, Gudermann T, Dietrich A. An Inhibitory Function of TRPA1 Channels in TGF-ß1-driven Fibroblast-to-Myofibroblast Differentiation. Am J Respir Cell Mol Biol. 2023 03; 68(3):314-325.
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Tjong J, Pendlmayr S, Barter J, Chen J, Maksym GN, Quinn TA, Frampton JP. Cell-contact-mediated assembly of contractile airway smooth muscle rings. Biomed Mater. 2023 03 01; 18(2).
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Rubino M, Travers JG, Headrick AL, Enyart BT, Lemieux ME, Cavasin MA, Schwisow JA, Hardy EJ, Kaltenbacher KJ, Felisbino MB, Jonas E, Ambardekar AV, Bristow MR, Koch KA, McKinsey TA. Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart. Circ Res. 2023 01 06; 132(1):10-29.
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Kabat AM, Hackl A, Sanin DE, Zeis P, Grzes KM, Baixauli F, Kyle R, Caputa G, Edwards-Hicks J, Villa M, Rana N, Curtis JD, Castoldi A, Cupovic J, Dreesen L, Sibilia M, Pospisilik JA, Urban JF, Grün D, Pearce EL, Pearce EJ. Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection. Sci Immunol. 2022 10 21; 7(76):eadd3263.
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Zeitlmayr S, Zierler S, Staab-Weijnitz CA, Dietrich A, Geiger F, Horgen FD, Gudermann T, Breit A. TRPM7 restrains plasmin activity and promotes transforming growth factor-ß1 signaling in primary human lung fibroblasts. Arch Toxicol. 2022 10; 96(10):2767-2783.
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Zhang L, Hu J, Meshkat BI, Liechty KW, Xu J. LncRNA MALAT1 Modulates TGF-ß1-Induced EMT in Keratinocyte. Int J Mol Sci. 2021 Oct 30; 22(21).
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