 RNA, Messenger
"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
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| MeSH Number(s) |
D13.444.735.544
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| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 12 | 37 | 49 | | 1995 | 7 | 34 | 41 | | 1996 | 2 | 42 | 44 | | 1997 | 3 | 43 | 46 | | 1998 | 11 | 43 | 54 | | 1999 | 4 | 40 | 44 | | 2000 | 7 | 48 | 55 | | 2001 | 2 | 36 | 38 | | 2002 | 9 | 45 | 54 | | 2003 | 9 | 76 | 85 | | 2004 | 13 | 70 | 83 | | 2005 | 6 | 67 | 73 | | 2006 | 10 | 82 | 92 | | 2007 | 9 | 61 | 70 | | 2008 | 13 | 53 | 66 | | 2009 | 11 | 49 | 60 | | 2010 | 11 | 51 | 62 | | 2011 | 15 | 44 | 59 | | 2012 | 20 | 50 | 70 | | 2013 | 9 | 47 | 56 | | 2014 | 14 | 44 | 58 | | 2015 | 10 | 59 | 69 | | 2016 | 14 | 39 | 53 | | 2017 | 9 | 40 | 49 | | 2018 | 12 | 38 | 50 | | 2019 | 14 | 20 | 34 | | 2020 | 12 | 32 | 44 | | 2021 | 9 | 24 | 33 | | 2022 | 1 | 49 | 50 | | 2023 | 1 | 29 | 30 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM, Reigan P, Rissland OS, Kieft JS. The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure. 2024 Apr 04; 32(4):400-410.e4.
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Barrington CL, Galindo G, Koch AL, Horton ER, Morrison EJ, Tisa S, Stasevich TJ, Rissland OS. Synonymous codon usage regulates translation initiation. Cell Rep. 2023 12 26; 42(12):113413.
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Powell TL, Barentsen K, Vaughan O, Uhlson C, Zemski Berry K, Erickson K, Faer K, Chassen SS, Jansson T. Knockdown of Placental Major Facilitator Superfamily Domain Containing 2a in Pregnant Mice Reduces Fetal Brain Growth and Phospholipid Docosahexaenoic Acid Content. Nutrients. 2023 Nov 29; 15(23).
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Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2024 05 01; 79(5):986-1004.
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Yang Q, Meyerson NR, Paige CL, Morrison JH, Clark SK, Fattor WT, Decker CJ, Steiner HR, Lian E, Larremore DB, Perera R, Poeschla EM, Parker R, Dowell RD, Sawyer SL. Human mRNA in saliva can correctly identify individuals harboring acute infection. mBio. 2023 Dec 19; 14(6):e0171223.
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Farmer T, Vaeth KF, Han KJ, Goering R, Taliaferro MJ, Prekeris R. The role of midbody-associated mRNAs in regulating abscission. J Cell Biol. 2023 12 04; 222(12).
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Mansouri-Noori F, Pircher A, Bilodeau D, Siniavskaia L, Grigull J, Rissland OS, Bayfield MA. The LARP1 homolog Slr1p controls the stability and expression of proto-5'TOP mRNAs in fission yeast. Cell Rep. 2023 10 31; 42(10):113226.
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Hamm DC, Paatela EM, Bennett SR, Wong CJ, Campbell AE, Wladyka CL, Smith AA, Jagannathan S, Hsieh AC, Tapscott SJ. The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. PLoS Biol. 2023 09; 21(9):e3002317.
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Maldonado L?pez AM, Ko EK, Huang S, Pacella G, Kuprasertkul N, D'souza CA, Reyes Hueros RA, Shen H, Stoute J, Elashal H, Sinkfield M, Anderson A, Prouty S, Li HB, Seykora JT, Liu KF, Capell BC. Mettl3-catalyzed m6A regulates histone modifier and modification expression in self-renewing somatic tissue. Sci Adv. 2023 09; 9(35):eadg5234.
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Maurina SF, O'Sullivan JP, Sharma G, Pineda Rodriguez DC, MacFadden A, Cendali F, Henen MA, V?geli B, Kieft JS, Glasgow A, Steckelberg AL. An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by ?-coronavirus Non-structural Protein 1. J Mol Biol. 2023 10 15; 435(20):168259.
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