TRPC Cation Channels
"TRPC Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.
Descriptor ID |
D050052
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MeSH Number(s) |
D12.776.157.530.400.901.500 D12.776.543.585.400.901.500
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Concept/Terms |
TRPC Cation Channels- TRPC Cation Channels
- Cation Channels, TRPC
- Channels, TRPC Cation
- Transient Receptor Potential Channels, Type C
- Transient Receptor Potential Cation Channel Subfamily C
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Below are MeSH descriptors whose meaning is more general than "TRPC Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPC Cation Channels".
This graph shows the total number of publications written about "TRPC Cation Channels" by people in this website by year, and whether "TRPC Cation Channels" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2010 | 2 | 0 | 2 | 2012 | 1 | 0 | 1 | 2016 | 2 | 0 | 2 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPC Cation Channels" by people in Profiles.
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Sharma A, Nakade UP, Akash R, Yadav VP, Choudhury S, Jaitley P, Sharma V, Garg SK. Calcium signaling cascades differentially regulate PGF2a-induced myometrial contractions in water buffaloes (Bubalus bubalis). Naunyn Schmiedebergs Arch Pharmacol. 2021 08; 394(8):1651-1664.
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Zhang Y, Knight W, Chen S, Mohan A, Yan C. Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival. Circulation. 2018 10 30; 138(18):1988-2002.
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Sharma A, Nakade UP, Choudhury S, Garg SK. Functional involvement of protein kinase C, Rho-kinase and TRPC3 decreases while PLC increases with advancement of pregnancy in mediating oxytocin-induced myometrial contractions in water buffaloes (Bubalus bubalis). Theriogenology. 2017 Apr 01; 92:176-189.
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Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, Zwickenpflug W, Flockerzi V, Storch U, Yildirim A?, Gudermann T, K?nigshoff M, Dietrich A. Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim Biophys Acta Mol Basis Dis. 2017 02; 1863(2):560-568.
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Klipec WD, Burrow KR, O'Neill C, Cao JL, Lawyer CR, Ostertag E, Fowler M, Bachtell RK, Illig KR, Cooper DC. Loss of the trpc4 gene is associated with a reduction in cocaine self-administration and reduced spontaneous ventral tegmental area dopamine neuronal activity, without deficits in learning for natural rewards. Behav Brain Res. 2016 06 01; 306:117-27.
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Gonzales AL, Yang Y, Sullivan MN, Sanders L, Dabertrand F, Hill-Eubanks DC, Nelson MT, Earley S. A PLC?1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries. Sci Signal. 2014 May 27; 7(327):ra49.
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Flood TF, Gorczyca M, White BH, Ito K, Yoshihara M. A large-scale behavioral screen to identify neurons controlling motor programs in the Drosophila brain. G3 (Bethesda). 2013 Oct 03; 3(10):1629-37.
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Peng F, Yao H, Akturk HK, Buch S. Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3beta. PLoS One. 2012; 7(10):e47572.
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Mace KE, Lussier MP, Boulay G, Terry-Powers JL, Parfrey H, Perraud AL, Riches DW. TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling. J Cell Physiol. 2010 Nov; 225(2):444-53.
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Terry Powers JL, Mace KE, Parfrey H, Lee SJ, Zhang G, Riches DW. TNF receptor-1 (TNF-R1) ubiquitous scaffolding and signaling protein interacts with TNF-R1 and TRAF2 via an N-terminal docking interface. Biochemistry. 2010 Sep 14; 49(36):7821-9.
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