Double-Blind Method
 
																	
																		 
																	
																		
																	 
																	
																		 
																	
																		
																	 
																	
																			
																					
	"Double-Blind Method" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
    
			 
			
				
				
					
						| Descriptor ID | 
										
							D004311
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						| MeSH Number(s) | 
						
							 E05.318.780.300 E05.581.500.300 N05.715.360.780.320 N06.850.520.445.300 
						 | 
					 
					
						| Concept/Terms | 
						
							Double-Blind Method- Double-Blind Method
 - Double Blind Method
 - Double-Blind Methods
 - Method, Double-Blind
 - Methods, Double-Blind
 - Double-Masked Method
 - Double Masked Method
 - Double-Masked Methods
 - Method, Double-Masked
 - Methods, Double-Masked
 - Double-Masked Study
 - Double Masked Study
 - Double-Masked Studies
 - Studies, Double-Masked
 - Study, Double-Masked
 - Double-Blind Study
 - Double Blind Study
 - Double-Blind Studies
 - Studies, Double-Blind
 - Study, Double-Blind
 
  
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				Below are MeSH descriptors whose meaning is more general than "Double-Blind Method". 
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Double-Blind Method". 
				
			 
		 
	 
 
																				
																					
	
	
		
			
			
					
				This graph shows the total number of publications written about "Double-Blind Method" by people in this website by year, and whether "Double-Blind Method" was a major or minor topic of these publications.  
				
					 
                    To see the data from this visualization as text,  click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 0 | 14 | 14 |  | 1996 | 0 | 23 | 23 |  | 1997 | 0 | 19 | 19 |  | 1998 | 0 | 20 | 20 |  | 1999 | 0 | 22 | 22 |  | 2000 | 0 | 22 | 22 |  | 2001 | 0 | 25 | 25 |  | 2002 | 0 | 26 | 26 |  | 2003 | 1 | 30 | 31 |  | 2004 | 0 | 43 | 43 |  | 2005 | 0 | 43 | 43 |  | 2006 | 0 | 44 | 44 |  | 2007 | 0 | 35 | 35 |  | 2008 | 0 | 46 | 46 |  | 2009 | 0 | 52 | 52 |  | 2010 | 0 | 48 | 48 |  | 2011 | 0 | 52 | 52 |  | 2012 | 0 | 52 | 52 |  | 2013 | 0 | 54 | 54 |  | 2014 | 1 | 81 | 82 |  | 2015 | 0 | 70 | 70 |  | 2016 | 0 | 77 | 77 |  | 2017 | 0 | 72 | 72 |  | 2018 | 0 | 82 | 82 |  | 2019 | 0 | 81 | 81 |  | 2020 | 0 | 77 | 77 |  | 2021 | 0 | 68 | 68 |  | 2022 | 0 | 47 | 47 |  | 2023 | 0 | 49 | 49 |  | 2024 | 0 | 69 | 69 |  | 2025 | 0 | 65 | 65 |  
 
                    To return to the timeline,  click here.
                 
			 	
			
			
			
			
				Below are the most recent publications written about "Double-Blind Method" by people in Profiles. 
						
					
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Cherney DZI, Belmar N, Bjornstad P, Chacko MM, Gunnarsson TP, Hodgin JB, Kretzler M, Pruijm M, Schytz PA, Tuttle KR. Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease. Nephrol Dial Transplant. 2025 Oct 30; 40(11):2182-2192. 
															
								 
							
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Strickland JC, Tilton HE, Patton NM, Vandrey R, Austin Zamarripa C, Spindle TR, Lee DC, Bergeria CL, Wolinsky D, Klawitter J, Sempio C, Campos-Palomino J, Christians U, Feldner MT, Irons JG, Bonn-Miller MO. Effect of caffeine and cannabidiol (CBD) co-administration on ?9-tetrahydrocannabinol (?9-THC) subjective effects, performance impairment, and pharmacokinetics. Neuropsychopharmacology. 2025 Nov; 50(12):1827-1835. 
															
								 
							
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Leaf DE, Shenoy T, Zinchuk K, Gupta S, Dias JA, Sanchez-Almanzar D, Ginde AA, Athar H, Cheng C, Tamura T, Kim EY, Waikar SS. Randomized trial of activated vitamin D for acute kidney injury prevention in critically ill patients. JCI Insight. 2025 Oct 22; 10(20). 
															
								 
							
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Brooks Peterson M, Boyd J, Zhu A, Bothwell S, Prager JD. Seeking a Viable Alternative: A Prospective, Randomized, Controlled, Double-Blind Non-Inferiority Study of Oral Versus IV Dexamethasone in Children Undergoing Tonsillectomy. Paediatr Anaesth. 2025 Nov; 35(11):953-961. 
															
								 
							
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McMichael A, Shahriari M, Stein Gold L, Alkousakis T, Choi O, Bhutani T, Rodriguez AO, Tyring SK, Chan D, Rowland K, Albrecht L, Lynde C, Yadav G, Yeung J, Park-Wyllie L, Ma T, Jeyarajah J, Gao LL, Smith S, Moore AY, Vashi N, Kindred C, Grimes P, Desai SR, Taylor SC, Alexis A. Guselkumab for Moderate to Severe Scalp Psoriasis Across All Skin Tones: Cohort B of the VISIBLE Randomized Clinical Trial. JAMA Dermatol. 2025 Sep 01; 161(9):912-922. 
															
								 
							
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Rasouli N, Guder Arslan E, Catarig AM, Houlind K, Ludvik B, Nordanstig J, Sourij H, Thomas S, Verma S, Bonaca MP. Benefit of Semaglutide in Symptomatic Peripheral Artery Disease by Baseline Type 2 Diabetes Characteristics: Insights From STRIDE, a Randomized, Placebo-Controlled, Double-Blind Trial. Diabetes Care. 2025 Sep 01; 48(9):1529-1535. 
															
								 
							
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Verma S, Leiter LA, Teoh H, Mancini GBJ, Quan A, Elituv R, Verma M, Misner E, Szarek M, Thorpe KE, Saha T, Whitlock RP, Yanagawa B, Merkely B, Jüni P, Koren MJ, Nicholls SJ, Bhatt DL, Mazer CD. Effect of evolocumab on saphenous vein graft patency after coronary artery bypass surgery (NEWTON-CABG CardioLink-5): an international, randomised, double-blind, placebo-controlled trial. Lancet. 2025 Sep 20; 406(10509):1223-1234. 
															
								 
							
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Nicholls SJ, Nelson AJ, Ray KK, Ballantyne CM, Ditmarsch M, Kling D, Hsieh A, Szarek M, Kastelein JJ, Davidson MH. Impact of Obicetrapib on Major Adverse Cardiovascular Events in High-Risk Patients: A Pooled Analysis. J Am Coll Cardiol. 2025 Oct 07; 86(14):1046-1056. 
															
								 
							
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Alexis A, McMichael A, Soung J, Choi O, Alkousakis T, Alonso-Llamazares J, Shahriari M, Rodriguez AO, Bhutani T, Chan D, Rowland K, Sauder M, Hong HC, Yadav G, Yeung J, Jeyarajah J, Ma T, Gao LL, Park-Wyllie L, Green L, Lee M, Vashi N, Kindred C, Grimes P, Taylor SC, Desai SR. Guselkumab for Moderate to Severe Psoriasis Across All Skin Tones: Cohort A of the VISIBLE Randomized Clinical Trial. JAMA Dermatol. 2025 Sep 01; 161(9):901-911. 
															
								 
							
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Butler J, McMullan CJ, Anstrom KJ, Barash I, Bonaca MP, Borentain M, Corda S, Ezekowitz JA, Felker GM, Gates D, Lam CSP, Lewis EF, Lindenfeld J, Mentz RJ, O'Connor CM, Ponikowski P, Reddy YNV, Rosano GMC, Saldarriaga C, Senni M, She L, Teixeira PP, Udelson J, Urbinati A, Vlajnic V, Voors AA, Xing A, Patel MJ, Zannad F. Vericiguat in patients with chronic heart failure and reduced ejection fraction (VICTOR): a double-blind, placebo-controlled, randomised, phase 3 trial. Lancet. 2025 Sep 27; 406(10510):1341-1350. 
															
								 
							
				 	
			 	
			
			
		 
	 
 
       
																				
                                                                            
																		
																	 
																 
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