 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1996 | 1 | 3 | 4 | | 1997 | 7 | 5 | 12 | | 1998 | 4 | 4 | 8 | | 1999 | 1 | 4 | 5 | | 2000 | 4 | 1 | 5 | | 2001 | 2 | 4 | 6 | | 2002 | 5 | 4 | 9 | | 2003 | 7 | 11 | 18 | | 2004 | 2 | 8 | 10 | | 2005 | 1 | 10 | 11 | | 2006 | 6 | 15 | 21 | | 2007 | 1 | 10 | 11 | | 2008 | 1 | 11 | 12 | | 2009 | 5 | 7 | 12 | | 2010 | 1 | 6 | 7 | | 2011 | 2 | 8 | 10 | | 2012 | 5 | 8 | 13 | | 2013 | 2 | 5 | 7 | | 2014 | 3 | 9 | 12 | | 2015 | 1 | 5 | 6 | | 2016 | 4 | 8 | 12 | | 2017 | 1 | 9 | 10 | | 2018 | 4 | 5 | 9 | | 2019 | 3 | 1 | 4 | | 2020 | 2 | 7 | 9 | | 2021 | 4 | 4 | 8 | | 2022 | 3 | 5 | 8 | | 2023 | 5 | 1 | 6 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Kant R, Mishra N, Kandhari K, Saba L, Michel C, Reisdorph R, Tewari-Singh N, Pantcheva MB, Petrash JM, Agarwal C, Agarwal R. Dexamethasone targets actin cytoskeleton signaling and inflammatory mediators to reverse sulfur mustard-induced toxicity in rabbit corneas. Toxicol Appl Pharmacol. 2024 02; 483:116834.
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Hoffman HK, Prekeris R. HOPS-dependent lysosomal fusion controls Rab19 availability for ciliogenesis in polarized epithelial cells. J Cell Sci. 2024 03 01; 137(5).
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Feng D, Xiang X, Guan Y, Guillot A, Lu H, Chang C, He Y, Wang H, Pan H, Ju C, Colgan SP, Tacke F, Wang XW, Kunos G, Gao B. Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models. J Clin Invest. 2023 08 01; 133(15).
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Sendo S, Kiosses WB, Yang S, Wu DJ, Lee DWK, Liu L, Aschner Y, Vela AJ, Downey GP, Santelli E, Bottini N. Clustering of phosphatase RPTPa promotes Src signaling and the arthritogenic action of synovial fibroblasts. Sci Signal. 2023 07 04; 16(792):eabn8668.
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Figueroa NE, Franz P, Luzarowski M, Martinez-Seidel F, Moreno JC, Childs D, Ziemblicka A, Sampathkumar A, Andersen TG, Tsiavaliaris G, Chodasiewicz M, Skirycz A. Protein interactome of 3',5'-cAMP reveals its role in regulating the actin cytoskeleton. Plant J. 2023 09; 115(5):1214-1230.
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Lee LA, Barrick SK, Buvoli AE, Walklate J, Stump WT, Geeves M, Greenberg MJ, Leinwand LA. Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b. J Biol Chem. 2023 05; 299(5):104631.
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Striepen JF, Voeltz GK. Endosome biogenesis is controlled by ER and the cytoskeleton at tripartite junctions. Curr Opin Cell Biol. 2023 02; 80:102155.
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Micke KC, Stence NV, Meyers ML, Chatfield KC, Vemulakonda VM. Megacystis Associated With an Underlying ACTA2 Variant and Diagnosis of Multisystemic Smooth Muscle Dysfunction Syndrome: A Case Report. Urology. 2023 03; 173:e17-e19.
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Johnson JL, Meneses-Salas E, Ramadass M, Monfregola J, Rahman F, Carvalho Gontijo R, Kiosses WB, Pestonjamasp K, Allen D, Zhang J, Osborne DG, Zhu YP, Wineinger N, Askari K, Chen D, Yu J, Henderson SC, Hedrick CC, Ursini MV, Grinstein S, Billadeau DD, Catz SD. Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation. Nat Commun. 2022 09 21; 13(1):5529.
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Striepen JF, Voeltz GK. Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission. J Cell Biol. 2022 08 01; 221(8).
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