 Catalytic Domain
"Catalytic Domain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The region of an enzyme that interacts with its substrate to cause the enzymatic reaction.
| Descriptor ID |
D020134
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| MeSH Number(s) |
G02.111.570.120.704 G02.111.570.820.709.275.750.188
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| Concept/Terms |
Catalytic Domain- Catalytic Domain
- Catalytic Domains
- Domain, Catalytic
- Domains, Catalytic
- Catalytic Subunit
- Catalytic Subunits
- Subunit, Catalytic
- Subunits, Catalytic
- Catalytic Region
- Catalytic Regions
- Region, Catalytic
- Regions, Catalytic
- Catalytic Core
- Catalytic Cores
- Core, Catalytic
- Cores, Catalytic
Active Site- Active Site
- Active Sites
- Site, Active
- Sites, Active
- Catalytic Site
- Catalytic Sites
- Site, Catalytic
- Sites, Catalytic
- Reactive Site
- Reactive Sites
- Site, Reactive
- Sites, Reactive
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Below are MeSH descriptors whose meaning is more general than "Catalytic Domain".
Below are MeSH descriptors whose meaning is more specific than "Catalytic Domain".
This graph shows the total number of publications written about "Catalytic Domain" by people in this website by year, and whether "Catalytic Domain" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 2 | 3 | 5 | | 2000 | 0 | 8 | 8 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 5 | 5 | | 2004 | 1 | 4 | 5 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 3 | 3 | | 2007 | 0 | 4 | 4 | | 2008 | 0 | 5 | 5 | | 2009 | 1 | 6 | 7 | | 2010 | 1 | 8 | 9 | | 2011 | 0 | 6 | 6 | | 2012 | 2 | 7 | 9 | | 2013 | 1 | 15 | 16 | | 2014 | 1 | 5 | 6 | | 2015 | 0 | 12 | 12 | | 2016 | 2 | 7 | 9 | | 2017 | 0 | 6 | 6 | | 2018 | 1 | 7 | 8 | | 2019 | 0 | 7 | 7 | | 2020 | 0 | 7 | 7 | | 2021 | 1 | 7 | 8 | | 2022 | 0 | 5 | 5 | | 2023 | 1 | 5 | 6 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Catalytic Domain" by people in Profiles.
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Briganti L, Manzine LR, de Mello Capetti CC, de Ara?jo EA, de Oliveira Arnoldi Pellegrini V, Guimaraes FEG, de Oliveira Neto M, Polikarpov I. Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies. Int J Biol Macromol. 2024 Aug; 274(Pt 2):133182.
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Kellett T, Noor R, Zhou Q, Esquer H, Sala R, Stojanovic P, Rudolph J, Luger K, LaBarbera DV. HTS discovery of PARP1-HPF1 complex inhibitors in cancer. SLAS Discov. 2023 12; 28(8):394-401.
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Pegram L, Riccardi D, Ahn N. Activation Loop Plasticity and Active Site Coupling in the MAP Kinase, ERK2. J Mol Biol. 2023 12 01; 435(23):168309.
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Friedman AJ, Padgette HM, Kramer L, Liechty ET, Donovan GW, Fox JM, Shirts MR. Biophysical Rationale for the Selective Inhibition of PTP1B over TCPTP by Nonpolar Terpenoids. J Phys Chem B. 2023 10 05; 127(39):8305-8316.
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Liechty ET, Hren A, Kramer L, Donovan G, Friedman AJ, Shirts MR, Fox JM. Analysis of neutral mutational drift in an allosteric enzyme. Protein Sci. 2023 08; 32(8):e4719.
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Lee E, Redzic JS, Zohar Eisenmesser E. Relaxation and single site multiple mutations to identify and control allosteric networks. Methods. 2023 08; 216:51-57.
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Ledvina HE, Ye Q, Gu Y, Sullivan AE, Quan Y, Lau RK, Zhou H, Corbett KD, Whiteley AT. An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature. 2023 04; 616(7956):319-325.
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Wilson TR, Morgenstern A, Alexandrova AN, Eberhart ME. Bond Bundle Analysis of Ketosteroid Isomerase. J Phys Chem B. 2022 11 24; 126(46):9443-9456.
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Friedman AJ, Liechty ET, Kramer L, Sarkar A, Fox JM, Shirts MR. Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid. J Phys Chem B. 2022 10 27; 126(42):8427-8438.
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Born A, Soetbeer J, Henen MA, Breitgoff F, Polyhach Y, Jeschke G, V?geli B. Ligand-specific conformational change drives interdomain allostery in Pin1. Nat Commun. 2022 08 04; 13(1):4546.
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