 Tumor Suppressor Proteins
"Tumor Suppressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
| Descriptor ID |
D025521
|
| MeSH Number(s) |
D12.776.624.776
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Proteins".
This graph shows the total number of publications written about "Tumor Suppressor Proteins" by people in this website by year, and whether "Tumor Suppressor Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 2 | 3 | | 1999 | 4 | 0 | 4 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 3 | 3 | 6 | | 2003 | 4 | 4 | 8 | | 2004 | 2 | 8 | 10 | | 2005 | 4 | 7 | 11 | | 2006 | 7 | 7 | 14 | | 2007 | 6 | 5 | 11 | | 2008 | 8 | 0 | 8 | | 2009 | 9 | 9 | 18 | | 2010 | 2 | 4 | 6 | | 2011 | 8 | 2 | 10 | | 2012 | 9 | 2 | 11 | | 2013 | 7 | 4 | 11 | | 2014 | 8 | 5 | 13 | | 2015 | 8 | 4 | 12 | | 2016 | 5 | 2 | 7 | | 2017 | 8 | 4 | 12 | | 2018 | 5 | 3 | 8 | | 2019 | 2 | 2 | 4 | | 2020 | 4 | 3 | 7 | | 2021 | 3 | 4 | 7 | | 2022 | 2 | 0 | 2 | | 2023 | 3 | 2 | 5 | | 2024 | 2 | 4 | 6 | | 2025 | 2 | 2 | 4 | | 2026 | 3 | 3 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Tumor Suppressor Proteins" by people in Profiles.
-
Jafree DJ, Russell LG, Stathopoulou A, O'Riordan C, Rowan CJ, White AT, Kolatsi-Joannou M, Price KL, Ivins S, Ridge LA, Roberts C, Rose A, Webb S, Vijayabaskar MS, Chandler JC, Wilson L, Pomeranz G, Moulding D, Davis B, Mitchell H, Siegenthaler J, Haniffa M, Woolf AS, Riley PR, Ruhrberg C, Scambler PJ, Rosenblum ND, Long DA. Osr1-expressing mesoderm contributes to lymphatic vessel assembly and complexity in the mammalian kidney. Cell Rep. 2026 Jul 28; 45(7):117560.
-
Zhou Y, Nakajima R, Shirasawa M, Fikriyanti M, Kitagawa M, San TY, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K. Murine Embryonic Stem Cells Possess Distinct E2F Activity That Activates Tumor Suppressor Promoter Elements. Genes Cells. 2026 May; 31(3):e70121.
-
Bidany-Mizrahi T, Maroun K, Mancini M, Hidmi O, Ansari I, Monin J, Keidar Haran T, Maly A, Melino G, Candi E, Aqeilan RI. WWOX maintains epidermal identity and suppresses EMT to prevent aggressive cutaneous squamous cell carcinoma. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2534844123.
-
Federico A, Schmitt-Hoffner F, Fonseca A, Geisemeyer N, Bruckner K, Mauermann M, Sill M, Stichel D, Sturm D, Schüller U, Tauziede-Espariat A, Varlet P, Capper D, Abdullaev Z, Schrimpf D, Selt F, Williamson L, Donson AM, Antonelli M, Miele E, Snuderl M, Brandner S, Lastowska M, van der Lugt J, Bunt J, Kramm C, Kolenova A, Raghunathan A, Wilson Y, Weintraub L, Hansford JR, Spiegl-Kreinecker S, Aistleitner B, Baroni L, Zapotocky M, Ramaswamy V, Korshunov A, Jones B, Kjaersgaard M, Kranendonk ME, Haberler C, Packer RJ, Jäger N, von Deimling A, Sahm F, Koster J, Aldape K, Pfister SM, von Hoff K, Gojo J, Kool M. Molecular and clinical stratification of astroblastomas: Three distinct fusion-defined groups informing risk-adapted treatment strategies. Neuro Oncol. 2026 Apr 01; 28(4):1005-1019.
-
Selvam K, Lu S, Messmer C, Pang Y, Biswas S, Khalil M, Zhang P, Tulaiha R, Zhou MM, Kitamura T, Lauberth SM, Blanco MA, Yang FC, Affar EB, Zhao Z, Zeng L, Wang L, Kutateladze TG. Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4. Nat Commun. 2026 Feb 17; 17(1).
-
Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
-
Campwala I, Schienda J, Murphy AJ, Hashimi B, Perry T, Cost N, Kamihara J, Mullen EA, Santiago T, Malek MM. Wilms Tumor in Children With AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series. Pediatr Blood Cancer. 2025 Aug; 72(8):e31798.
-
Fleming JL, Pugh SL, Chang SM, McElroy JP, Becker AP, Aldape KD, Shih HA, Ashby LS, Hunter GK, Bahary JP, Schultz CJ, Kavanagh BD, Puduvalli VK, Robins HI, Werner-Wasik M, Mehta M, Chakravarti A. Comprehensive Molecular Analysis in NRG Oncology/RTOG 9813: A Phase 3 Study of Radiation and Temozolomide Versus Radiation and BCNU/CCNU in Anaplastic Astrocytoma. Int J Radiat Oncol Biol Phys. 2025 09 01; 123(1):84-92.
-
Flynn A, Pattison AD, Balachander S, Boehm E, Bowen B, Dwight T, Rossello FJ, Hofmann O, Martelotto L, Zethoven M, Kirschner LS, Else T, Fishbein L, Gill AJ, Tischler AS, Giordano T, Prodanov T, Noble JR, Reddel RR, Trainer AH, Ghayee HK, Bourdeau I, Elston M, Ishak D, Ngeow Yuen Yie J, Hicks RJ, Crona J, Åkerström T, Stålberg P, Dahia P, Grimmond S, Clifton-Bligh R, Pacak K, Tothill RW. Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles. Nat Commun. 2025 Mar 17; 16(1):2632.
-
Biswas S, Lee JE, Xie G, Masclef L, Ren Z, Côté J, Affar EB, Ge K, Kutateladze TG. Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction. J Biol Chem. 2025 03; 301(3):108333.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|