 Tumor Suppressor Proteins
"Tumor Suppressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
| Descriptor ID |
D025521
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| MeSH Number(s) |
D12.776.624.776
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Proteins".
This graph shows the total number of publications written about "Tumor Suppressor Proteins" by people in this website by year, and whether "Tumor Suppressor Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 2 | 1 | 3 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 2 | 3 | | 1999 | 3 | 0 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 3 | 3 | 6 | | 2003 | 4 | 4 | 8 | | 2004 | 2 | 8 | 10 | | 2005 | 4 | 7 | 11 | | 2006 | 7 | 7 | 14 | | 2007 | 6 | 5 | 11 | | 2008 | 8 | 0 | 8 | | 2009 | 9 | 8 | 17 | | 2010 | 2 | 4 | 6 | | 2011 | 8 | 2 | 10 | | 2012 | 8 | 2 | 10 | | 2013 | 7 | 4 | 11 | | 2014 | 8 | 5 | 13 | | 2015 | 8 | 4 | 12 | | 2016 | 6 | 2 | 8 | | 2017 | 8 | 4 | 12 | | 2018 | 5 | 3 | 8 | | 2019 | 2 | 2 | 4 | | 2020 | 4 | 3 | 7 | | 2021 | 2 | 4 | 6 | | 2022 | 2 | 0 | 2 | | 2023 | 3 | 2 | 5 | | 2024 | 2 | 4 | 6 | | 2025 | 2 | 2 | 4 | | 2026 | 4 | 5 | 9 |
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Below are the most recent publications written about "Tumor Suppressor Proteins" by people in Profiles.
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Zhang S, Singh O, Dazelle K, Quezado M, Cimino PJ, Abdullaev Z, Wu J, Lucas CH, Schreck KC, Holdhoff M, Pytel P, Goodwill V, Macaulay R, McDonald W, Seidman R, Wood M, Bharani K, Neltner J, Richard H, Chang K, Szymanski L, Yip S, Mukherjee A, Lopes Abath Neto O, Sharma SJ, Green R, Brown D, Gubbiotti MA, Ballester LY, Eschbacher J, Smith-Cohn M, Gokden M, Vincentelli C, Yong W, Lee J, Mount C, Fulmer J, Sun M, Ligon K, Santi M, Pai EL, Yeaney G, Alexandrescu S, Raghavan R, Fernandes I, Reis GF, Mandel J, Caccamo D, Rao S, Butt OH, Dahiya S, Stone S, Conway K, Nasrallah MP, Fuller C, Toland A, Lukas RV, Cachia D, Uhlmann EJ, McCord M, Helgager J, Han K, Perry A, Perez S, Daoud E, BeDell D, Highfield H, Kobalka P, Nix JS, Nduom E, Neill S, Gilbert MR, Lakis N, Fonseca A, Shen C, Yoda R, Monterroza L, Cohen AL, Cathcart S, Al Amin M, Campian J, Aldape K. High-grade astrocytoma with piloid features: A clinical and genomic analysis of prognostic factors using a large cohort. Neuro Oncol. 2026 Oct 01; 28(10):2435-2448.
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Clements CM, Roney MSI, Shellman YG. SASH1 as a Context-Dependent Multi-Docking Scaffold Linking Receptor Signaling to Cytoskeletal Dynamics. Int J Mol Sci. 2026 Aug 06; 27(15).
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Gaurav N, Ebert LK, Lachance C, Selvam K, Chen RW, Qin W, Pozharskaia V, Chi C, Côté V, Cox KL, Fuchs HA, Musselman CA, Leonhardt H, Morral N, Song K, Poirier MG, Côté J, Schermer B, Kutateladze TG. Distinct roles of the JADE and BRPF scaffolding subunits of the acetyltransferase HBO1 complex. Nat Commun. 2026 Jul 11; 17(1).
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Jafree DJ, Russell LG, Stathopoulou A, O'Riordan C, Rowan CJ, White AT, Kolatsi-Joannou M, Price KL, Ivins S, Ridge LA, Roberts C, Rose A, Webb S, Vijayabaskar MS, Chandler JC, Wilson L, Pomeranz G, Moulding D, Davis B, Mitchell H, Siegenthaler J, Haniffa M, Woolf AS, Riley PR, Ruhrberg C, Scambler PJ, Rosenblum ND, Long DA. Osr1-expressing mesoderm contributes to lymphatic vessel assembly and complexity in the mammalian kidney. Cell Rep. 2026 Jul 28; 45(7):117560.
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Zhou Y, Nakajima R, Shirasawa M, Fikriyanti M, Kitagawa M, San TY, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K. Murine Embryonic Stem Cells Possess Distinct E2F Activity That Activates Tumor Suppressor Promoter Elements. Genes Cells. 2026 May; 31(3):e70121.
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Bidany-Mizrahi T, Maroun K, Mancini M, Hidmi O, Ansari I, Monin J, Keidar Haran T, Maly A, Melino G, Candi E, Aqeilan RI. WWOX maintains epidermal identity and suppresses EMT to prevent aggressive cutaneous squamous cell carcinoma. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2534844123.
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Federico A, Schmitt-Hoffner F, Fonseca A, Geisemeyer N, Bruckner K, Mauermann M, Sill M, Stichel D, Sturm D, Schüller U, Tauziede-Espariat A, Varlet P, Capper D, Abdullaev Z, Schrimpf D, Selt F, Williamson L, Donson AM, Antonelli M, Miele E, Snuderl M, Brandner S, Lastowska M, van der Lugt J, Bunt J, Kramm C, Kolenova A, Raghunathan A, Wilson Y, Weintraub L, Hansford JR, Spiegl-Kreinecker S, Aistleitner B, Baroni L, Zapotocky M, Ramaswamy V, Korshunov A, Jones B, Kjaersgaard M, Kranendonk ME, Haberler C, Packer RJ, Jäger N, von Deimling A, Sahm F, Koster J, Aldape K, Pfister SM, von Hoff K, Gojo J, Kool M. Molecular and clinical stratification of astroblastomas: Three distinct fusion-defined groups informing risk-adapted treatment strategies. Neuro Oncol. 2026 Apr 01; 28(4):1005-1019.
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Selvam K, Lu S, Messmer C, Pang Y, Biswas S, Khalil M, Zhang P, Tulaiha R, Zhou MM, Kitamura T, Lauberth SM, Blanco MA, Yang FC, Affar EB, Zhao Z, Zeng L, Wang L, Kutateladze TG. Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4. Nat Commun. 2026 Feb 17; 17(1).
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Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Campwala I, Schienda J, Murphy AJ, Hashimi B, Perry T, Cost N, Kamihara J, Mullen EA, Santiago T, Malek MM. Wilms Tumor in Children With AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series. Pediatr Blood Cancer. 2025 08; 72(8):e31798.
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