 Genetic Predisposition to Disease
"Genetic Predisposition to Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
| Descriptor ID |
D020022
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| MeSH Number(s) |
C23.550.291.687.500 G05.380.355
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| Concept/Terms |
Genetic Predisposition to Disease- Genetic Predisposition to Disease
- Genetic Susceptibility
- Genetic Susceptibilities
- Susceptibilities, Genetic
- Susceptibility, Genetic
- Genetic Predisposition
- Genetic Predispositions
- Predispositions, Genetic
- Predisposition, Genetic
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Below are MeSH descriptors whose meaning is more general than "Genetic Predisposition to Disease".
Below are MeSH descriptors whose meaning is more specific than "Genetic Predisposition to Disease".
This graph shows the total number of publications written about "Genetic Predisposition to Disease" by people in this website by year, and whether "Genetic Predisposition to Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 5 | 3 | 8 | | 2000 | 8 | 7 | 15 | | 2001 | 7 | 12 | 19 | | 2002 | 12 | 13 | 25 | | 2003 | 13 | 14 | 27 | | 2004 | 17 | 20 | 37 | | 2005 | 21 | 20 | 41 | | 2006 | 25 | 27 | 52 | | 2007 | 20 | 33 | 53 | | 2008 | 27 | 37 | 64 | | 2009 | 24 | 36 | 60 | | 2010 | 32 | 49 | 81 | | 2011 | 28 | 47 | 75 | | 2012 | 25 | 53 | 78 | | 2013 | 36 | 50 | 86 | | 2014 | 35 | 50 | 85 | | 2015 | 37 | 72 | 109 | | 2016 | 31 | 48 | 79 | | 2017 | 46 | 55 | 101 | | 2018 | 31 | 66 | 97 | | 2019 | 50 | 62 | 112 | | 2020 | 20 | 34 | 54 | | 2021 | 25 | 56 | 81 | | 2022 | 9 | 38 | 47 | | 2023 | 5 | 35 | 40 | | 2024 | 18 | 32 | 50 | | 2025 | 17 | 50 | 67 | | 2026 | 4 | 2 | 6 |
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Below are the most recent publications written about "Genetic Predisposition to Disease" by people in Profiles.
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Lawrence JM, Foote IF, Breunig S, Schaffer LS, Lyons S, Abramowitz SA, Levin MG, Damrauer SM, Mallard TT, Grotzinger AD. Shared Genetic Liability across Systems of Psychiatric and Physical Illness. Nat Commun. 2026 Feb 21; 17(1).
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Zhang C, Konigsberg IR, He Y, Zhang J, Chikowore T, Feldman WB, Hu X, Ding Y, Pasaniuc B, Chang D, Chen Q, Lasky-Su JA, Hecker J, Tobin MD, Chen J, Kalra S, Pratte KA, Im HK, Wan ES, Manichaikul A, Silverman EK, Bowler RP, Lange LA, Ortega VE, Martin AR, Cho MH, Moll MR. Multi-trait polygenic scores for COPD and COPD exacerbations implicate druggable proteins. JCI Insight. 2026 Apr 08; 11(7).
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Aydemir O, Bailey JA, Agardh D, Lernmark Å, Noble JA, Andersson Svärd A, Blankenhorn EP, Parikh HM, Ziegler AG, Toppari J, Akolkar B, Hagopian WA, Rewers MJ, Mordes JP. Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. Elife. 2026 Feb 02; 12.
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Steck AK, Parikh HM, Triolo TM, Ferrat L, You L, Gottlieb PA, Oram RA, Onengut-Gumuscu S, Krischer JP, Rich SS, Redondo MJ. Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e493-e499.
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Vollenbrock CE, Roshandel D, Lee KE, Klein BE, Mul D, van der Klauw MM, Tack CJ, Rewers M, Snell-Bergeon JK, Costacou T, Miller RG, Caramori ML, Mauer M, Aanstoot HJ, Wolffenbuttel BHR, Paterson AD. Association of genetic variation with age at diagnosis in type 1 diabetes. BMJ Open Diabetes Res Care. 2026 Jan 16; 14(1).
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Fortis S, Comellas AP, Bowler RP, Bhatt SP, Hersh CP, Demeo DL, Kinney G, Silverman EK, Cho MH, Moll M. Relationships between bronchodilator responsiveness, a COPD polygenic risk score, and COPD progression. Respir Med. 2026 02; 252:108636.
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Small AM, Yang TY, Itoh S, Thériault S, Dufresne L, Kurosawa R, Komuro I, Matsuda K, Vy HMT, Farber-Eger EH, Shaffer LL, Boulier KM, Corey KM, Ramaker ME, Laporte F, Schott JJ, Le Scouarnec S, Singh SA, Sonawane AR, Smith HA, Rafaels N, Ghouse J, Raja AA, Ostrowski SR, Sørensen E, Mikkelsen C, Pedersen OB, Erikstrup C, Ullum H, Sveinbjornsson G, Gudbjartsson DF, Abner E, Lee J, Ganna A, Nowak-Göttl U, Finer S, Schumacher J, Maj C, Al-Kassou B, Nickenig G, Trenkwalder T, Dreßen M, Krane M, Nöthen MM, Moksnes MR, Brumpton BM, Knight S, Knowlton KU, Nadauld L, Debiec R, Musameh MD, Braund PS, Nelson CP, Czuba T, Melander O, Selvaraj MS, Koyama S, Bhukar R, Ruan Y, Ljungberg J, Damrauer SM, Levin MG, Franke A, Berger K, Ruff CT, Melloni GEM, Kamanu FK, Ito K, Do R, Loos RJF, Schunkert H, Wells QS, Shah SH, Le Tourneau T, Messika-Zeitoun D, Gignoux C, Bundgaard H, Larsson SC, Michaëlsson K, Holm H, Helgadottir A, Esko T, van Heel DA, Mathieu P, Samani NJ, Smith JG, Söderberg S, Rader DJ, Marston NA, Sabatine MS, Pasaniuc B, Cho K, Wilson PWF, O'Donnell CJ, Stefansson K, Bossé Y, Aikawa E, Engert JC, Peloso GM, Natarajan P, Thanassoulis G. Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nat Genet. 2026 Jan; 58(1):57-66.
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Veijola R, Tamura RN, Clasen JL, Elding Larsson H, Warncke K, Steck AK, Haller MJ, Jonsdottir B, Akolkar B, Hagopian WA, Rewers MJ, She JX, Ziegler AG, Krischer JP, Toppari J. Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity. Diabetologia. 2026 Mar; 69(3):643-652.
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Natarajan R, Szczesny B, Kanchan K, Esquinca E, Boorgula MP, Chavan S, Campbell M, Lorizio W, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola G, Sogaolu O, Falade AG, Hansel NN, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Kenny EE, Ruczinski I, Liu AH, Ober C, Taub MA, Johnson RK, Barnes KC, Wojcik GL, Mathias RA. Mediation of Polygenic Asthma Risk Through Gene Expression. Allergy. 2026 Apr; 81(4):1089-1098.
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Raghavan S, Litkowski E, Jensen A, Charest B, Wang Z, Hui Q, Chen HC, Rhee MK, Leong A, Meigs JB, Lange L, Lange E, Reaven P, Hung A, Zhou J, Sun YV, Phillips LS. Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program. Diabetes. 2025 Dec 01; 74(12):2432-2443.
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