 Protein Domains
"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
| Descriptor ID |
D000072417
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| MeSH Number(s) |
G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
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| Concept/Terms |
Protein Domains- Protein Domains
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domain
- Domain, Protein
- Domains, Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Domains".
Below are MeSH descriptors whose meaning is more specific than "Protein Domains".
This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 | | 2016 | 0 | 20 | 20 | | 2017 | 0 | 23 | 23 | | 2018 | 4 | 18 | 22 | | 2019 | 2 | 25 | 27 | | 2020 | 1 | 20 | 21 | | 2021 | 3 | 19 | 22 | | 2022 | 1 | 10 | 11 | | 2023 | 0 | 3 | 3 | | 2024 | 2 | 11 | 13 | | 2025 | 0 | 18 | 18 |
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Below are the most recent publications written about "Protein Domains" by people in Profiles.
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Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158.
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Saeb D, Lietzke EE, Fuchs DI, Aldrich EC, Bruce KD, Sprenger KG. The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids. Elife. 2025 Sep 10; 13.
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Sardar M, Ahmad N, Mushtaq M, Heinz H, Nur-E-Alam M, Ul-Haq Z. Unveiling Ligand-Induced Conformational Changes in Mutant AR-LBD: Molecular Dynamics Insights into the Androgen Receptor-Coactivator Mechanism. J Chem Inf Model. 2025 Sep 08; 65(17):9154-9176.
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Kumar A, Sakuraba S, Gaurav N, Selvam K, Kutateladze TG, Kono H. Mechanistic Insights into HP1a CSD Oligomerization and the Role of PxVxL Motif-Containing Proteins. J Chem Inf Model. 2025 Aug 25; 65(16):8768-8780.
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Tan XF, Fernández-Mariño AI, Li Y, Chang TH, Swartz KJ. Structural basis of fast N-type inactivation in Kv channels. Nature. 2025 Sep; 645(8082):1081-1089.
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Pratt J, McCann K, Kuo J, Parker R. Polyserine-tau interactions modulate tau fibrillization. J Biol Chem. 2025 Sep; 301(9):110523.
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Gordon BH, Ogunkunle VS, Silvers R. Noncanonical RNA binding of human La-related protein 6. Nucleic Acids Res. 2025 Jul 19; 53(14).
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Van Keuren AM, Simoes CT, Tucker CL. Chemical Control of Protease Activity and Gene Expression Using a Biotin-Released Inhibitory Domain. ACS Synth Biol. 2025 Aug 15; 14(8):3065-3077.
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Guo XS, Khalifa A, Selvam K, Kutateladze TG, Liu WR. Development of Chemical Tools for the Human YEATS Domain. ACS Chem Biol. 2025 Aug 15; 20(8):1828-1840.
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Becht DC, Biswas S, Xu C, Xuan H, Khalil M, Cai L, Musselman CA, Liu X, Affar EB, Shi X, Wang GG, Kutateladze TG. Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300. Biochem J. 2025 Jul 02; 482(13):955-968.
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