 Protein Domains
"Protein Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
| Descriptor ID |
D000072417
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| MeSH Number(s) |
G02.111.570.820.709.275.750 G02.111.570.820.709.610.500
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| Concept/Terms |
Protein Domains- Protein Domains
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domain
- Domain, Protein
- Domains, Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Domains".
Below are MeSH descriptors whose meaning is more specific than "Protein Domains".
This graph shows the total number of publications written about "Protein Domains" by people in this website by year, and whether "Protein Domains" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 | | 2016 | 0 | 19 | 19 | | 2017 | 0 | 21 | 21 | | 2018 | 4 | 19 | 23 | | 2019 | 2 | 25 | 27 | | 2020 | 1 | 21 | 22 | | 2021 | 3 | 19 | 22 | | 2022 | 1 | 10 | 11 | | 2023 | 0 | 3 | 3 | | 2024 | 2 | 11 | 13 | | 2025 | 0 | 22 | 22 | | 2026 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Domains" by people in Profiles.
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Selvam K, Lu S, Messmer C, Pang Y, Biswas S, Khalil M, Zhang P, Tulaiha R, Zhou MM, Kitamura T, Lauberth SM, Blanco MA, Yang FC, Affar EB, Zhao Z, Zeng L, Wang L, Kutateladze TG. Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4. Nat Commun. 2026 Feb 17; 17(1).
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Bai X, Zhang J, Wang S, Huang K, Pan Z, Liang A, Wu W, Yu Z, Chen Y, Tong Y, Dai S, Chen Z. Novel intermolecular zinc fingers and redox-driven conformational changes dictate tumor suppressor ZMYND11's role in cooperative recognition of diverse targets. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Byrom L, Turvey GL, Dowle AA, Thomas M, Shirodkar N, Green BJ, Brown M, Ball C, Chapman KE, Guglielmi E, Dickson W, Noon E, Sofi S, Ainscough JF, Antson AA, Coverley D. AURKB-driven dissolution of CIZ1-RNA assemblies from the inactive X chromosome in mitosis. Nucleic Acids Res. 2026 Jan 22; 54(3).
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Van Alstyne M, Nguyen VL, Hoeffer CA, Parker R. Polyserine domains are toxic and exacerbate tau pathology in mice. Proc Natl Acad Sci U S A. 2026 Jan 06; 123(1):e2527425122.
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Youle RL, Lista MJ, Brudenell EL, Thompson B, Bouton C, Morris ER, Neil SJD, Swanson CM, Taylor IA. KHNYN is a manganese-dependent endoribonuclease required for ZAP-mediated antiviral restriction. Nucleic Acids Res. 2025 Nov 26; 53(22).
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Ramirez DA, Shrimpton A, Shirts MR, Hough LE. Nonspecific interactions can lead to liquid-liquid phase separation in coiled-coil protein models. Biophys J. 2026 Jan 06; 125(1):218-234.
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Langdon N, Kroft C, Fang Q, Krall J, Rincon M, Vögeli B, Vicens Q, Henen MA. Cromolyn as a novel pharmacophore of the Za domain of the RNA-editing enzyme ADAR1p150. Protein Sci. 2025 Nov; 34(11):e70341.
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Sullivan AE, Nabhani A, Izrailevsky DS, Schinkel K, Hoffman CRK, Robbins LK, Nagy TA, Duncan ML, Ledvina HE, Erbse AH, Kibby EM, Tak U, Dinh DM, Ednacot EMQ, Nguyen CM, Burroughs AM, Aravind L, Whiteley AT, Morehouse BR. The Panoptes system uses decoy cyclic nucleotides to defend against phage. Nature. 2025 Nov; 647(8091):988-996.
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Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158.
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Saeb D, Lietzke EE, Fuchs DI, Aldrich EC, Bruce KD, Sprenger KG. The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids. Elife. 2025 Sep 10; 13.
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