Fibroblasts
"Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.
| Descriptor ID |
D005347
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| MeSH Number(s) |
A11.329.228
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Fibroblasts".
This graph shows the total number of publications written about "Fibroblasts" by people in this website by year, and whether "Fibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 6 | 6 | | 1997 | 0 | 6 | 6 | | 1998 | 1 | 10 | 11 | | 1999 | 2 | 9 | 11 | | 2000 | 4 | 11 | 15 | | 2001 | 4 | 8 | 12 | | 2002 | 6 | 11 | 17 | | 2003 | 7 | 9 | 16 | | 2004 | 7 | 11 | 18 | | 2005 | 8 | 16 | 24 | | 2006 | 10 | 10 | 20 | | 2007 | 9 | 13 | 22 | | 2008 | 9 | 17 | 26 | | 2009 | 6 | 11 | 17 | | 2010 | 6 | 17 | 23 | | 2011 | 6 | 15 | 21 | | 2012 | 11 | 7 | 18 | | 2013 | 14 | 14 | 28 | | 2014 | 19 | 10 | 29 | | 2015 | 9 | 11 | 20 | | 2016 | 15 | 12 | 27 | | 2017 | 11 | 22 | 33 | | 2018 | 12 | 14 | 26 | | 2019 | 11 | 13 | 24 | | 2020 | 12 | 17 | 29 | | 2021 | 11 | 20 | 31 | | 2022 | 0 | 19 | 19 | | 2023 | 2 | 13 | 15 | | 2024 | 9 | 9 | 18 | | 2025 | 13 | 13 | 26 | | 2026 | 8 | 4 | 12 |
To return to the timeline, click here.
Below are the most recent publications written about "Fibroblasts" by people in Profiles.
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Cooley JC, Penick SK, Wilson JA, Javkhlan N, Foster DG, Edelman BL, Schott CA, Humphries SM, Lynch DA, Schwartz DA, Riches DWH, Redente EF. Nintedanib increases BCL-2 in fibrotic fibroblasts, enhancing ABT-199 apoptosis and fibrosis resolution. Am J Respir Cell Mol Biol. 2026 Aug 01; 74(8):1103-1113.
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Mantel I, Zhang H, Vargas J, Ce G, Townsend H, Bell R, Lakhanpal A, Fein MR, Norman TM, Orange DE, Ramirez DC, DiCarlo EF, Goodman SM, Smith MH, Zhang F, Wei K, Dey KK, Rudensky AY, Leslie CS, Donlin LT. SPP1hi macrophages in fibrin niches promote hyperplastic tissue remodeling in rheumatoid arthritis synovium. Sci Transl Med. 2026 Jun 24; 18(855):eaed3087.
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Zlotnick HM, Goddard DN, Calo CJ, Dhand AP, Davidson MD, Solsona-Pujol A, Makhoul JT, Weppner HK, Wong M, Scanzello CR, Hind LE, Burdick JA. Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model. Proc Natl Acad Sci U S A. 2026 May 19; 123(20):e2524677123.
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Foster DG, Javkhlan N, Black BP, Vestal BE, Riches DW, Redente EF. Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repair. JCI Insight. 2026 Jul 08; 11(13).
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Magrinelli F, Tesson C, Angelova PR, Rodriguez JA, Scardamaglia A, O'Callaghan B, Lowe SA, Salazar-Villacorta A, Chung BH, Jaconelli M, Vona B, Esteras N, Mammana A, Shimazu J, Kwong AK, Courtin T, Alavi S, Maroofian R, Nirujogi R, Severino M, Monfrini E, Rocca C, Lewis PA, Efthymiou S, Buchert R, Sofan L, Lis P, Pinon C, Breedveld GJ, Chui MM, Murphy D, Pitz V, Makarious MB, Baiardi S, Volin M, Cassar M, Hassan BA, Iftikhar S, Bauer P, Tinazzi M, Svetel M, Samanci B, Hanagasi HA, Bilgiç B, Cavallieri F, Santangelo M, Obeso JA, Kurtis MM, Cogan G, Kiziltan G, Gül-Demirkale T, Tireli H, Yüksel GA, Yalçin-Cakmakli G, Elibol B, Bari?ic N, Ng EW, Fan SS, Hershkovitz T, Weiss K, Alvi JR, Sultan T, Alkhawaja IA, Froukh T, Alrukban HAE, Anjum MN, Saeed A, Cheema HA, Fauth C, Schatz UA, Zöggeler T, Zech M, Stals K, Varghese V, Gandhi S, Blauwendraat C, Hardy JA, Di Fonzo A, Bonifati V, Haack TB, Bertoli-Avella AM, Lesage S, Basak AN, Steinfeld R, Parchi P, Jepson JEC, Alessi DR, Brice A, Steller H, Abramov AY, Bhatia KP, Houlden H. Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality. Nat Commun. 2026 Apr 15; 17(1).
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Staab-Weijnitz CA, Merl-Pham J, Hennen E, Onursal C, Cabeza-Boeddinghaus N, Kandhari K, Stremlau M, Behr J, Hilgendorff A, Bächinger HP, Hauck SM, Vanacore R, Hansen KC, Basak T. Prolyl-3-hydroxylase 1 is a central regulator of collagen post-translational modifications and the collagen biosynthetic network. J Biol Chem. 2026 May; 302(5):111422.
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Redente EF, Song T, Javkhlan N, Edelman BL, Foster DG, Wilson JA, Chakraborty S, Cooley JC, Gaurav R, Saguthi S, Seibold MA, Blumhagen RZ, Schwartz DA, Yang IV, Matsuda J, Bridges JP, Zemans RL, Tuder RM, Riches DWH. Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition. Nat Commun. 2026 Feb 28; 17(1).
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Bertino F, Zanin Venturini DI, Grasso E, Kopecka J, Salio C, Gnutti B, Basnet RM, Bellini S, Mignani L, Zhao B, Kleefeld F, Hentschel A, Magnani F, Fiorito V, Abalai RE, Metani L, Allocco AL, Petrillo S, De Giorgio F, Ammirata G, Salsano E, Pareyson D, di Rocco M, Abicht A, McCourt E, Horvath R, Kölbel H, Larson A, Roos A, Yu TW, Finazzi D, Riganti C, Tolosano E, Chiabrando D. Mitochondrial energetic failure underlies FLVCR1-related sensory neuropathy. Commun Biol. 2026 Feb 14; 9(1).
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Verhaege D, De Nolf C, Van Acker L, Claeys W, Castelein J, Van Wonterghem E, Van Imschoot G, Dujardin P, De Spiegelaere W, Hoste E, Boone F, Lidov HGW, Dani N, Derk J, Kremer A, Van Hamme E, Borghgraef P, Lippens S, Lehtinen MK, Siegenthaler J, Van Hoecke L, Vandenbroucke RE. Base barrier cells provide compartmentalization of choroid plexus, brain and CSF. Nat Neurosci. 2026 Mar; 29(3):551-566.
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Shaikh FS, Shanta MA, Singh AK, Daniels AM, Khuder SA, Thiele GM, Reed GW, Kremer JM, Pappas DA, Curtis JR, O'Dell JR, Ouseph MM, Fox DA, Ahmed S. TWEAK receptor (Fn14) exacerbates TNF-a-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to anti-TNF-a therapy. Cell Mol Immunol. 2026 Mar; 23(3):315-328.
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