 Reactive Oxygen Species
"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
| Descriptor ID |
D017382
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| MeSH Number(s) |
D01.339.431 D01.650.775
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| Concept/Terms |
Reactive Oxygen Species- Reactive Oxygen Species
- Oxygen Species, Reactive
- Active Oxygen
- Oxygen, Active
- Oxygen Radicals
- Pro-Oxidants
- Pro Oxidants
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Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".
Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".
This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 3 | 4 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 4 | 7 | 11 | | 2003 | 7 | 6 | 13 | | 2004 | 5 | 10 | 15 | | 2005 | 7 | 7 | 14 | | 2006 | 4 | 10 | 14 | | 2007 | 1 | 8 | 9 | | 2008 | 6 | 10 | 16 | | 2009 | 5 | 11 | 16 | | 2010 | 2 | 16 | 18 | | 2011 | 8 | 14 | 22 | | 2012 | 4 | 20 | 24 | | 2013 | 4 | 24 | 28 | | 2014 | 0 | 21 | 21 | | 2015 | 6 | 7 | 13 | | 2016 | 3 | 16 | 19 | | 2017 | 5 | 16 | 21 | | 2018 | 0 | 12 | 12 | | 2019 | 1 | 21 | 22 | | 2020 | 4 | 11 | 15 | | 2021 | 2 | 18 | 20 | | 2022 | 0 | 15 | 15 | | 2023 | 1 | 15 | 16 | | 2024 | 2 | 12 | 14 | | 2025 | 4 | 14 | 18 | | 2026 | 0 | 7 | 7 |
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Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.
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Orr L, Golding H, O'Brien E, Siauw J, Su TT. Pink1 represses apoptosis and allows proper morphogenesis after exposure to ionizing radiation in Drosophila melanogaster. Genetics. 2026 May 06; 233(1).
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Parween S, Saviola AJ, Howell AC, Varghese S, Galindo DC, Vergara MN. Human retinal organoid model of disease-relevant photoreceptor cell death amenable to drug screening. Cell Death Dis. 2026 Apr 13; 17(1).
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Grijalva-Flores D, Resendiz MJE. Ribonucleobase Oxidation and Ribonucleases Involved in the Degradation of Oxidized RNA. Biomolecules. 2026 Apr 10; 16(4).
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Morcom L, Xia W, Xu Z, Awasthi Y, Geywitz C, Ellis MO, Noli T, Zulji A, Yamamoto D, Girdler GC, Kai L, Zhu K, Wei M, Tang XY, Hoi KK, Gonzalez-Maya J, Duncan GJ, Vaquie AM, Gold Diaz D, Kawaguchi R, Liu E, Sun Y, Yang D, Jordan GD, Lu IL, Holmqvist S, Bartels T, Ridley K, Choi JJ, Franco SJ, Huang EJ, Emery B, Geschwind D, Schirmer L, Balmus G, Popko B, Fancy SPJ, Rowitch DH. DNA damage burden causes selective CUX2 neuron loss in neuroinflammation. Nature. 2026 May; 653(8115):809-818.
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Day BJ. Antioxidants in lung disease: Failures and pathways for success. Free Radic Biol Med. 2026 Jul; 250:216-223.
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Murray KO, Gioscia-Ryan RA, Justice JN, Santos-Parker JR, Bispham NZ, Hutton DA, Darvish S, Miyamoto-Ditmon J, Clayton ZS, Chonchol M, Seals DR, Rossman MJ. Translational studies of chronic supplementation with a mitochondria-targeted antioxidant to improve physical function with ageing. J Physiol. 2026 04; 604(7):2898-2922.
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Gu W, Ren Z, Gao J, Shen Z, Wang Y, Xu L, Qian R, Miao Q, Wu Y, Hu X, Wu Y, Liu W, Wan CC, Sun L, Cai Y, Sang M, Zheng C, Yan T. Inhibiting NAT10 suppresses hepatocellular carcinoma progression by reducing Nrf2 mRNA stability and increasing oxidative stress. Chem Biol Interact. 2026 Apr 25; 429:111972.
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Margolis A, Liu L, Kim J-S, Porwollik S, McClelland M, Vázquez-Torres A. Amino acid decarboxylation preserves Salmonella fitness during phagocyte-derived oxidative stress. mBio. 2026 Jan 14; 17(1):e0314725.
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Saunders EF, Schultz KR, Lowe I, Anderson AL, Bikkumalla VS, Soto D, Tran NY, Baumel-Alterzon S, Knight JD, Shearn CT. Rapid protein carbonylation and decreased insulin secretion induced by inflammatory oxidative stress compounds. Free Radic Biol Med. 2026 Jan; 242:320-332.
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Affandi T, Ohm AM, Speidel JT, Caino MC, Boulton DP, Reyland ME. PKCd Regulates DNA Damage and Cell Death through a SIRT6/Nrf2-dependent Antioxidant Response. Mol Cancer Res. 2025 Sep 04; 23(9):779-791.
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