 Reactive Oxygen Species
"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.
| Descriptor ID |
D017382
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| MeSH Number(s) |
D01.339.431 D01.650.775
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| Concept/Terms |
Reactive Oxygen Species- Reactive Oxygen Species
- Oxygen Species, Reactive
- Active Oxygen
- Oxygen, Active
- Oxygen Radicals
- Pro-Oxidants
- Pro Oxidants
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Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".
Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".
This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 | | 1996 | 1 | 3 | 4 | | 1997 | 0 | 3 | 3 | | 1998 | 0 | 1 | 1 | | 1999 | 1 | 2 | 3 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 3 | 3 | | 2002 | 3 | 7 | 10 | | 2003 | 7 | 6 | 13 | | 2004 | 5 | 10 | 15 | | 2005 | 8 | 7 | 15 | | 2006 | 4 | 10 | 14 | | 2007 | 1 | 8 | 9 | | 2008 | 6 | 9 | 15 | | 2009 | 5 | 11 | 16 | | 2010 | 2 | 14 | 16 | | 2011 | 8 | 13 | 21 | | 2012 | 4 | 19 | 23 | | 2013 | 5 | 22 | 27 | | 2014 | 0 | 19 | 19 | | 2015 | 5 | 8 | 13 | | 2016 | 3 | 14 | 17 | | 2017 | 6 | 14 | 20 | | 2018 | 1 | 12 | 13 | | 2019 | 1 | 21 | 22 | | 2020 | 4 | 10 | 14 | | 2021 | 2 | 18 | 20 | | 2022 | 0 | 17 | 17 | | 2023 | 1 | 13 | 14 | | 2024 | 2 | 13 | 15 | | 2025 | 4 | 10 | 14 |
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Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.
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Affandi T, Ohm AM, Speidel JT, Caino MC, Boulton DP, Reyland ME. PKCd Regulates DNA Damage and Cell Death through a SIRT6/Nrf2-dependent Antioxidant Response. Mol Cancer Res. 2025 Sep 04; 23(9):779-791.
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Kumari N, Panja S, Kumar B, Ahmad R, Kollala SS, Siddhanta K, Islam F, Joshi V, Talmon GA, Murry DJ, Singh AB, Oupický D. Reactive Oxygen Species-Responsive Polymeric Chloroquine Nanogel for Targeted Oral Therapy of Ulcerative Colitis. ACS Appl Mater Interfaces. 2025 Sep 10; 17(36):50443-50463.
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Skuli SJ, Bakayoko A, Kruidenier M, Manning B, Pammer P, Salimov A, Riley O, Brake-Sillá G, Dopkin D, Bowman M, Martinez-Gutierrez LN, Anderson CC, Reisz JA, Buono R, Paul M, Saland E, Liccardo F, DeVine A, Wong S, Xu JP, Nee E, Hausler R, Boettcher S, Sebti SM, Lai C, Maxwell KN, Sarry JE, Fruman DA, D'Alessandro A, Mesaros C, Keith B, Simon MC, Sung PJ, Wertheim G, Skuli N, Bowman RL, Matthews A, Carroll M. Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response. Leukemia. 2025 Sep; 39(9):2087-2098.
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Heo J, Miller DL, Hoffman JR, Oberholtzer E, Castelli KM, Sparagna GC, Fisher-Wellman KH, Greising SM, Call JA. Acute mitochondrial reactive oxygen species emissions drive mitochondrial dysfunction after traumatic muscle injury in male mice. Am J Physiol Cell Physiol. 2025 Jul 01; 329(1):C235-C250.
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Berry AR, Ruzzene ST, Ostrander EI, Wegerson KN, Orozco-Fersiva NC, Stone MF, Valenti WB, Izaias JE, Holzer JP, Greiner JJ, Garcia VP, DeSouza CA. The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function. J Appl Physiol (1985). 2025 Jun 01; 138(6):1571-1577.
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Elajaili H, Lyttle BD, Lewis CV, Bardill JR, Dee N, Seal S, Nozik ES, Liechty KW, Zgheib C. Increased ROS and Persistent Pro-Inflammatory Responses in a Diabetic Wound Healing Model (db/db): Implications for Delayed Wound Healing. Int J Mol Sci. 2025 May 20; 26(10).
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Kroon S, Malcic D, Weidert L, Bircher L, Boldt L, Christen P, Kiefer P, Sintsova A, Nguyen BD, Barthel M, Steiger Y, Clerc M, Herzog MK, Chen C, Gül E, Guery B, Slack E, Sunagawa S, Vorholt JA, Maier L, Lacroix C, Hausmann A, Hardt WD. Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition. Nat Commun. 2025 Mar 20; 16(1):2760.
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Lesbats J, Brillac A, Reisz JA, Mukherjee P, Lhuissier C, Fern?ndez-Monreal M, Dupuy JW, Sequeira A, Tioli G, De La Calle Arregui C, Pinson B, Wendisch D, Rousseau B, Efeyan A, Sander LE, D'Alessandro A, Garaude J. Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses. Nature. 2025 Apr; 640(8058):524-533.
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Stem AD, Michel CR, Harris PS, Rogers KL, Gibb M, Roncal-Jimenez CA, Reisdorph R, Johnson RJ, Roede JR, Fritz KS, Brown JM. Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology. Part Fibre Toxicol. 2025 Feb 06; 22(1):3.
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Sun X, Yegambaram M, Lu Q, Garcia Flores AE, Pokharel MD, Soto J, Aggarwal S, Wang T, Fineman JR, Black SM. Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2. Redox Biol. 2025 Apr; 81:103529.
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