 Tubulin
"Tubulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
| Descriptor ID |
D014404
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| MeSH Number(s) |
D05.750.078.734.800 D12.776.220.600.800 D12.776.631.920
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tubulin".
Below are MeSH descriptors whose meaning is more specific than "Tubulin".
This graph shows the total number of publications written about "Tubulin" by people in this website by year, and whether "Tubulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 4 | 4 | | 2002 | 1 | 1 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 3 | 5 | | 2005 | 3 | 4 | 7 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 5 | 6 | | 2009 | 2 | 1 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 3 | 5 | | 2012 | 1 | 3 | 4 | | 2013 | 1 | 0 | 1 | | 2014 | 3 | 2 | 5 | | 2015 | 5 | 5 | 10 | | 2016 | 3 | 2 | 5 | | 2017 | 3 | 2 | 5 | | 2019 | 2 | 1 | 3 | | 2020 | 4 | 0 | 4 | | 2021 | 2 | 1 | 3 | | 2022 | 3 | 1 | 4 | | 2023 | 4 | 0 | 4 | | 2024 | 4 | 0 | 4 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tubulin" by people in Profiles.
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Wood LM, Moore JK. ?3 accelerates microtubule plus end maturation through a divergent lateral interface. Mol Biol Cell. 2025 Apr 01; 36(4):ar36.
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Ju JA, Thompson KN, Annis DA, Mull ML, Gilchrist DE, Moriarty A, Chang KT, Stemberger MB, Noto MJ, Vitolo MI, Martin SS. Tubulin-Based Microtentacles Aid in Heterotypic Clustering of Neutrophil-Differentiated HL-60 Cells and Breast Tumor Cells. Adv Sci (Weinh). 2025 Feb; 12(6):e2409260.
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Thomas EC, Moore JK. Selective regulation of kinesin-5 function by ?-tubulin carboxy-terminal tails. J Cell Biol. 2025 Mar 03; 224(3).
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Rissland OS. What tubulin can teach us about gene regulation. Nat Rev Genet. 2024 Aug; 25(8):531.
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Gonzalez SJ, Heckel JM, Goldblum RR, Reid TA, McClellan M, Gardner MK. Rapid binding to protofilament edge sites facilitates tip tracking of EB1 at growing microtubule plus-ends. Elife. 2024 Feb 22; 13.
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Ceglowski J, Hoffman HK, Neumann AJ, Hoff KJ, McCurdy BL, Moore JK, Prekeris R. TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells. EMBO Rep. 2024 Jan; 25(1):198-227.
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Wethekam LC, Moore JK. a-tubulin regulation by 5' introns in Saccharomyces cerevisiae. Genetics. 2023 12 06; 225(4).
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Stemberger MB, Ju JA, Thompson KN, Mathias TJ, Jerrett AE, Chang KT, Ory EC, Annis DA, Mull ML, Gilchrist DE, Vitolo MI, Martin SS. Hydrogen Peroxide Induces a-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes. Cells. 2023 04 27; 12(9).
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Wethekam LC, Moore JK. Tubulin isotype regulation maintains asymmetric requirement for a-tubulin over ?-tubulin. J Cell Biol. 2023 03 06; 222(3).
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Guyomar C, Bousquet C, Ku S, Heumann JM, Guilloux G, Gaillard N, Heichette C, Duchesne L, Steinmetz MO, Gibeaux R, Chr?tien D. Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts. Elife. 2022 12 12; 11.
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