 Tubulin
"Tubulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
| Descriptor ID |
D014404
|
| MeSH Number(s) |
D05.750.078.734.800 D12.776.220.600.800 D12.776.631.920
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tubulin".
Below are MeSH descriptors whose meaning is more specific than "Tubulin".
This graph shows the total number of publications written about "Tubulin" by people in this website by year, and whether "Tubulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 2 | 3 | | 2001 | 0 | 3 | 3 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 3 | 5 | | 2005 | 3 | 4 | 7 | | 2006 | 1 | 3 | 4 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 5 | 6 | | 2009 | 2 | 1 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 2 | 4 | | 2012 | 1 | 3 | 4 | | 2013 | 1 | 0 | 1 | | 2014 | 3 | 2 | 5 | | 2015 | 5 | 4 | 9 | | 2016 | 3 | 2 | 5 | | 2017 | 3 | 2 | 5 | | 2019 | 2 | 1 | 3 | | 2020 | 4 | 0 | 4 | | 2021 | 1 | 0 | 1 | | 2022 | 3 | 1 | 4 | | 2023 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Tubulin" by people in Profiles.
-
Ceglowski J, Hoffman HK, Neumann AJ, Hoff KJ, McCurdy BL, Moore JK, Prekeris R. TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells. EMBO Rep. 2024 Jan; 25(1):198-227.
-
Wethekam LC, Moore JK. a-tubulin regulation by 5' introns in Saccharomyces cerevisiae. Genetics. 2023 12 06; 225(4).
-
Wethekam LC, Moore JK. Tubulin isotype regulation maintains asymmetric requirement for a-tubulin over ?-tubulin. J Cell Biol. 2023 03 06; 222(3).
-
Guyomar C, Bousquet C, Ku S, Heumann JM, Guilloux G, Gaillard N, Heichette C, Duchesne L, Steinmetz MO, Gibeaux R, Chr?tien D. Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts. Elife. 2022 12 12; 11.
-
Wethekam LC, Moore JK. Microtubule cytoskeleton: Revealing new readers of?the tubulin code. Curr Biol. 2022 09 26; 32(18):R960-R962.
-
Dwyer-Nield LD, McArthur DG, Hudish TM, Hudish LI, Mirita C, Sompel K, Smith AJ, Alavi K, Ghosh M, Merrick DT, Tennis MA, Keith RL. PPARgamma agonism inhibits progression of premalignant lesions in a murine lung squamous cell carcinoma model. Int J Cancer. 2022 Dec 15; 151(12):2195-2205.
-
Hoff KJ, Aiken JE, Gutierrez MA, Franco SJ, Moore JK. TUBA1A tubulinopathy mutants disrupt neuron morphogenesis and override XMAP215/Stu2 regulation of microtubule dynamics. Elife. 2022 05 05; 11.
-
Moore JK, Wethekam L. Specialist a-tubulins for pluralist microtubules. J Cell Biol. 2021 12 06; 220(12).
-
Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 04 15; 10.
-
Siegel D, Bersie S, Harris P, Di Francesco A, Armstrong M, Reisdorph N, Bernier M, de Cabo R, Fritz K, Ross D. A redox-mediated conformational change in NQO1 controls binding to microtubules and a-tubulin acetylation. Redox Biol. 2021 02; 39:101840.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|