 Protein Kinase C-epsilon
"Protein Kinase C-epsilon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.
| Descriptor ID |
D051744
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.725.750
|
| Concept/Terms |
Protein Kinase C-epsilon- Protein Kinase C-epsilon
- Kinase C-epsilon, Protein
- PKC-epsilon Serine Threonine Kinase
- PKC epsilon Serine Threonine Kinase
- Protein Kinase C epsilon
- PKC epsilon
|
Below are MeSH descriptors whose meaning is more general than "Protein Kinase C-epsilon".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C-epsilon".
This graph shows the total number of publications written about "Protein Kinase C-epsilon" by people in this website by year, and whether "Protein Kinase C-epsilon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2004 | 0 | 3 | 3 | | 2005 | 2 | 1 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Kinase C-epsilon" by people in Profiles.
-
Yang J, Bassuk AG, Merl-Pham J, Hsu CW, Colgan DF, Li X, Au KS, Zhang L, Smemo S, Justus S, Nagahama Y, Grossbach AJ, Howard MA, Kawasaki H, Feldstein NA, Dobyns WB, Northrup H, Hauck SM, Ueffing M, Mahajan VB, Tsang SH. Catenin delta-1 (CTNND1) phosphorylation controls the mesenchymal to epithelial transition in astrocytic tumors. Hum Mol Genet. 2016 10 01; 25(19):4201-4210.
-
Lin YH, Warren CM, Li J, McKinsey TA, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016 08; 28(8):1015-24.
-
Cantley JL, Yoshimura T, Camporez JP, Zhang D, Jornayvaz FR, Kumashiro N, Guebre-Egziabher F, Jurczak MJ, Kahn M, Guigni BA, Serr J, Hankin J, Murphy RC, Cline GW, Bhanot S, Manchem VP, Brown JM, Samuel VT, Shulman GI. CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1869-74.
-
Caino MC, Lopez-Haber C, Kissil JL, Kazanietz MG. Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon. PLoS One. 2012; 7(2):e31714.
-
Caino MC, Lopez-Haber C, Kim J, Mochly-Rosen D, Kazanietz MG. Proteins kinase C? is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes. Oncogene. 2012 May 17; 31(20):2593-600.
-
Filone CM, Hanna SL, Caino MC, Bambina S, Doms RW, Cherry S. Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon. PLoS One. 2010 Nov 24; 5(11):e15483.
-
Tang J, Bouyer P, Mykoniatis A, Buschmann M, Matlin KS, Matthews JB. Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. J Biol Chem. 2010 Oct 29; 285(44):34072-85.
-
Meshki J, Caino MC, von Burstin VA, Griner E, Kazanietz MG. Regulation of prostate cancer cell survival by protein kinase Cepsilon involves bad phosphorylation and modulation of the TNFalpha/JNK pathway. J Biol Chem. 2010 Aug 20; 285(34):26033-40.
-
Edwards AG, Rees ML, Gioscia RA, Zachman DK, Lynch JM, Browder JC, Chicco AJ, Moore RL. PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance to myocardial infarction. J Physiol. 2009 Dec 01; 587(Pt 23):5723-37.
-
Xiao L, Caino MC, von Burstin VA, Oliva JL, Kazanietz MG. Phorbol ester-induced apoptosis and senescence in cancer cell models. Methods Enzymol. 2008; 446:123-39.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|