 Gene Knockdown Techniques
"Gene Knockdown Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
| Descriptor ID |
D055785
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| MeSH Number(s) |
E05.393.335.500
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| Concept/Terms |
Gene Knockdown Techniques- Gene Knockdown Techniques
- Gene Knockdown Technique
- Knockdown Technique, Gene
- Knockdown Techniques, Gene
- Technique, Gene Knockdown
- Techniques, Gene Knockdown
- Gene Knockdown
- Gene Knockdowns
- Knockdown, Gene
- Knockdowns, Gene
- Gene Knock-Down
- Gene Knock-Downs
- Knock-Down, Gene
- Knock-Downs, Gene
- Gene Knock-Down Techniques
- Gene Knock-Down Technique
- Knock-Down Technique, Gene
- Knock-Down Techniques, Gene
- Technique, Gene Knock-Down
- Techniques, Gene Knock-Down
- Gene Knock Down
- Gene Knock Downs
- Knock Down, Gene
- Knock Downs, Gene
- Gene Knock Down Techniques
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Below are MeSH descriptors whose meaning is more general than "Gene Knockdown Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knockdown Techniques".
This graph shows the total number of publications written about "Gene Knockdown Techniques" by people in this website by year, and whether "Gene Knockdown Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 2 | 2 | | 2009 | 2 | 15 | 17 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 10 | 10 | | 2012 | 1 | 24 | 25 | | 2013 | 2 | 19 | 21 | | 2014 | 0 | 25 | 25 | | 2015 | 0 | 13 | 13 | | 2016 | 1 | 19 | 20 | | 2017 | 0 | 14 | 14 | | 2018 | 0 | 13 | 13 | | 2019 | 1 | 12 | 13 | | 2020 | 0 | 8 | 8 | | 2021 | 0 | 11 | 11 | | 2024 | 0 | 1 | 1 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Knockdown Techniques" by people in Profiles.
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Lee GY, Schaunaman N, Nouri HR, Kraft M, Chu HW. Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells. BMC Res Notes. 2025 Apr 23; 18(1):194.
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Kramer A, Vaughan OR, Barentsen K, Urschitz J, Powell TL, Jansson T, Rosario FJ. Lentivirus-Mediated Trophoblast-Specific Deptor Knockdown Increases Transplacental System A and System L Amino Acid Transport and Fetal Growth in Mice. Function (Oxf). 2025 Mar 24; 6(2).
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Mejzini R, Caruthers MH, Schafer B, Kostov O, Sudheendran K, Ciba M, Danielsen M, Wilton S, Akkari PA, Flynn LL. Allele-Selective Thiomorpholino Antisense Oligonucleotides as a Therapeutic Approach for Fused-in-Sarcoma Amyotrophic Lateral Sclerosis. Int J Mol Sci. 2024 Aug 03; 25(15).
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Kratzel A, Kelly JN, V'kovski P, Portmann J, Br?ggemann Y, Todt D, Ebert N, Shrestha N, Plattet P, Staab-Weijnitz CA, von Brunn A, Steinmann E, Dijkman R, Zimmer G, Pfaender S, Thiel V. A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. PLoS Biol. 2021 12; 19(12):e3001490.
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Vaughan OR, Maksym K, Silva E, Barentsen K, Anthony RV, Brown TL, Hillman SL, Spencer R, David AL, Rosario FJ, Powell TL, Jansson T. Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice. Clin Sci (Lond). 2021 09 17; 135(17):2049-2066.
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Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 12; 74(6):3284-3300.
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Chen AW, Biggar K, Nygard K, Singal S, Zhao T, Li C, Nathanielsz PW, Jansson T, Gupta MB. IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Ca (PKCa). Mol Cell Endocrinol. 2021 10 01; 536:111400.
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Cole LK, Agarwal P, Doucette CA, Fonseca M, Xiang B, Sparagna GC, Seshadri N, Vandel M, Dolinsky VW, Hatch GM. Tafazzin Deficiency Reduces Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets From Male Mice. Endocrinology. 2021 07 01; 162(7).
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Soto RA, Najia MAT, Hachimi M, Frame JM, Yette GA, Lummertz da Rocha E, Stankunas K, Daley GQ, North TE. Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Reports. 2021 07 13; 16(7):1718-1734.
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Mannucci I, Dang NDP, Huber H, Murry JB, Abramson J, Althoff T, Banka S, Baynam G, Bearden D, Beleza-Meireles A, Benke PJ, Berland S, Bierhals T, Bilan F, Bindoff LA, Braathen GJ, Busk ?L, Chenbhanich J, Denecke J, Escobar LF, Estes C, Fleischer J, Groepper D, Haaxma CA, Hempel M, Holler-Managan Y, Houge G, Jackson A, Kellogg L, Keren B, Kiraly-Borri C, Kraus C, Kubisch C, Le Guyader G, Ljungblad UW, Brenman LM, Martinez-Agosto JA, Might M, Miller DT, Minks KQ, Moghaddam B, Nava C, Nelson SF, Parant JM, Prescott T, Rajabi F, Randrianaivo H, Reiter SF, Schuurs-Hoeijmakers J, Shieh PB, Slavotinek A, Smithson S, Stegmann APA, Tomczak K, Tveten K, Wang J, Whitlock JH, Zweier C, McWalter K, Juusola J, Quintero-Rivera F, Fischer U, Yeo NC, Kreienkamp HJ, Lessel D. Genotype-phenotype correlations and novel molecular insights into the DHX30-associated neurodevelopmental disorders. Genome Med. 2021 05 21; 13(1):90.
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