 Histones
"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
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| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 2 | 6 | 8 | | 2002 | 1 | 2 | 3 | | 2003 | 5 | 0 | 5 | | 2004 | 5 | 2 | 7 | | 2005 | 5 | 2 | 7 | | 2006 | 8 | 5 | 13 | | 2007 | 4 | 5 | 9 | | 2008 | 7 | 7 | 14 | | 2009 | 11 | 4 | 15 | | 2010 | 3 | 11 | 14 | | 2011 | 7 | 10 | 17 | | 2012 | 12 | 11 | 23 | | 2013 | 10 | 12 | 22 | | 2014 | 8 | 13 | 21 | | 2015 | 4 | 18 | 22 | | 2016 | 19 | 13 | 32 | | 2017 | 21 | 6 | 27 | | 2018 | 17 | 11 | 28 | | 2019 | 15 | 14 | 29 | | 2020 | 12 | 21 | 33 | | 2021 | 15 | 12 | 27 | | 2022 | 10 | 10 | 20 | | 2023 | 16 | 11 | 27 | | 2024 | 14 | 6 | 20 | | 2025 | 11 | 7 | 18 | | 2026 | 7 | 8 | 15 |
To return to the timeline, click here.
Below are the most recent publications written about "Histones" by people in Profiles.
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Lozzi B, Gatesman TA, Dasgupta P, Sardar D, Ko Y, Mao C, Chen HC, Curry RN, Choi D, Mohila CA, Bondy ML, Rao G, Gallo M, Agnihotri S, Deneen B. Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma. Proc Natl Acad Sci U S A. 2026 Jun 16; 123(24):e2601061123.
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Crowell C, Mankuzhy NP, Bennett J, Bandopadhayay P, Sturm D, Green AL, Gupta T, Chatterjee A, Epari S, Chinnaswamy G, Prasad M, Patel SH, MacNeil M, Vanan MI, Larouche V, Renzi S, Jones J, Perreault S, Mata-Mbemba D, Sangatsuda Y, Yoshimoto K, Lin E, Feddersen C, Cruz O, Pavon-Mengual M, Vizzini O, Zápotocký M, Popovacki A, Klawinski D, Hansford JR, Schlosser MP, Omene E, Alexander KL, Satgunaseelan L, Williams A, Yao K, Ronsley R, Cheng S, Ludlow L, Eisenstat D, Khuong-Quang DA, Tabouret E, André N, Matheson K, Chan A, Lim-Fat MJ, Lapointe S, Cayrol R, Coleman C, Juretic N, McThenia S, Khan S, Wright-Nadkarni M, Salloum R, Galvin RT, Sener U, Hawkins C, Imber BS, Karajannis MA, Jones DTW, Ligon KL, Jabado N, Erker C. Clinical Outcomes and Prognostic Features of Diffuse Hemispheric Glioma, H3 G34-Mutant: An International Multi-institutional Study. Clin Cancer Res. 2026 Jun 01; 32(11):2243-2254.
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Krug B, Hu B, Chen H, Negrón-Lomas C, Chen X, El Mouatani A, Gretarsson KH, Ptack A, Deshmukh S, Kabir N, Jawhar W, Andrade AF, Jabbour E, Harutyunyan AS, Wang X, Taylor R, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Yang J, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C. H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs. Nat Genet. 2026 Jun; 58(6):1368-1382.
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Song J, Yao L, Gooding AR, Thron V, Hemphill WO, Goodrich KJ, Erbse AH, Kasinath V, Cech TR. RNA-induced PRC2 inhibition depends on the sequence of bound RNA. Nat Commun. 2026 Apr 23; 17(1).
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Laursen SP, Luger K. Histone diversity in the archaeal domain of life. Nat Commun. 2026 Apr 15; 17(1).
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Rana PSJB, Foley JR, Bhattacharya M, Gloag ES, Wozniak DJ. Staphylococcus aureus biofilm extracellular DNA neutralizes the antimicrobial activity of histone H3. NPJ Biofilms Microbiomes. 2026 Apr 13; 12(1).
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Zhang H, Wei T, Panchenko AR, Musselman CA, Peng Y. MD2NMR: Linking molecular dynamics with NMR relaxation. Biophys J. 2026 Jun 02; 125(11):2555-2566.
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Bunner S, Huang K, Shah A, Figueroa S, Lang N, Chu C, Eskndir N, Pho M, Manning G, Zheng M, Fritz-Laylin L, Velle KB, Marcus J, Orth J, Stephens AD. Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity. J Cell Sci. 2026 Jun 15; 139(12).
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Ingersoll S, Trouth A, Angel JC, Luo X, Espinoza A, Wen J, Zhu C, Tucker J, Astatike K, Phiel CJ, Sabaawy H, Kutateladze TG, Wu TP, Yao T, Lu C, Ramachandran S, Ren X. Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes. Mol Cell. 2026 Mar 19; 86(6):1015-1031.e16.
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Rosas R, Baracaldo-Lancheros LF, Dykhuizen EC, Musselman CA. Structural landscape of H3K27me3 recognition by protein domains and their potential for inhibition. J Biol Chem. 2026 Apr; 302(4):111344.
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