 Binding Sites
"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
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| MeSH Number(s) |
G02.111.570.120
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| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 32 | 32 | | 1997 | 0 | 41 | 41 | | 1998 | 0 | 29 | 29 | | 1999 | 0 | 18 | 18 | | 2000 | 0 | 30 | 30 | | 2001 | 0 | 38 | 38 | | 2002 | 0 | 37 | 37 | | 2003 | 0 | 47 | 47 | | 2004 | 0 | 34 | 34 | | 2005 | 0 | 38 | 38 | | 2006 | 1 | 47 | 48 | | 2007 | 0 | 33 | 33 | | 2008 | 0 | 35 | 35 | | 2009 | 0 | 30 | 30 | | 2010 | 0 | 31 | 31 | | 2011 | 2 | 48 | 50 | | 2012 | 0 | 43 | 43 | | 2013 | 0 | 28 | 28 | | 2014 | 0 | 40 | 40 | | 2015 | 0 | 25 | 25 | | 2016 | 1 | 36 | 37 | | 2017 | 0 | 35 | 35 | | 2018 | 0 | 36 | 36 | | 2019 | 1 | 24 | 25 | | 2020 | 0 | 21 | 21 | | 2021 | 0 | 19 | 19 | | 2022 | 0 | 7 | 7 | | 2023 | 0 | 8 | 8 | | 2024 | 0 | 13 | 13 | | 2025 | 0 | 11 | 11 | | 2026 | 0 | 3 | 3 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Mead EH, Batz KC, Shih KH, Fleming IR, Tesdahl CD, Lizardos L, Armendariz JR, Hannan JP, Hickey AM, Leyk A, Erbse AH, Falke JJ. COSMIC-Linked Ras Mutations at the Interface Between H-Ras and PI3K?RBD Frequently Generate Affinity Increases. Biochemistry. 2026 Jun 02; 65(11):1749-1754.
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Kroft CW, Krall JB, Warchol M, Welty R, Herbert A, Henen MA, Vögeli B. Za and Zß domains of ADAR1 and ZBP1 bind G-quadruplexes with nanomolar affinities, establishing Zß as a G-quadruplex-specific domain. Nucleic Acids Res. 2026 Apr 23; 54(8).
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Biswas S, Tavaf Z, Benz C, Khalil M, Becht DC, Simonetti L, Blanco MA, Affar EB, Ivarsson Y, Kutateladze TG. A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3. J Biol Chem. 2026 Mar; 302(3):111189.
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Bhattacharjee B, Noviello CM, Rahman MM, Mayer JP, Gajewiak J, McIntosh JM, Hibbs RE, Stowell MHB. Shape-shifting conotoxins reveal divergent pore-targeting mechanisms in nicotinic receptors. Structure. 2026 Mar 05; 34(3):463-470.e4.
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Sears JD, Popov KI, Sylvester PA, Dickmander R, Diaz J, Chang CK, Huff J, Sanders W, Saba NA, Sorensen M, Drobish AM, May NA, Namitz K, Fecko J, Yennawar NH, Morrison TE, Tropsha A, Heise MT, Moorman NJ. Novel computational pipeline to identify target sites for broad spectrum antiviral drugs. Antiviral Res. 2026 01; 245:106322.
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Saeb D, Lietzke EE, Fuchs DI, Aldrich EC, Bruce KD, Sprenger KG. The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids. Elife. 2025 Sep 10; 13.
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Chan YS, Gao Q, Robinson SA, Wang W, Filandrova R, Weinhold LM, Cabrera ML, Zhang M, Ambati CSR, Lerario AM, Putluri N, Kiseljak-Vassiliades K, Wierman ME, Habra MA, Hammer GD, Veverka V, Cermakova K, Hodges HC. ß-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
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Gordon BH, Ogunkunle VS, Silvers R. Noncanonical RNA binding of human La-related protein 6. Nucleic Acids Res. 2025 Jul 19; 53(14).
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Siwik SH, Wierzba AJ, Lennon SR, Olenginski LT, Palmer AE, Batey RT. Structural basis for ring-opening fluorescence by the RhoBAST RNA aptamer. Nucleic Acids Res. 2025 Jun 20; 53(12).
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Young MA, Rees SD, Nicklisch SCT, Stowell MHB, Hamdoun A, Chang G. Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna. Environ Sci Technol. 2025 Jun 10; 59(22):11251-11260.
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