 Transcription Factors
"Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
| Descriptor ID |
D014157
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| MeSH Number(s) |
D12.776.930
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| Concept/Terms |
Transcription Factors- Transcription Factors
- Factors, Transcription
- Transcription Factor
- Factor, Transcription
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors".
This graph shows the total number of publications written about "Transcription Factors" by people in this website by year, and whether "Transcription Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 17 | 2 | 19 | | 1996 | 23 | 8 | 31 | | 1997 | 22 | 12 | 34 | | 1998 | 15 | 14 | 29 | | 1999 | 18 | 10 | 28 | | 2000 | 22 | 13 | 35 | | 2001 | 22 | 20 | 42 | | 2002 | 37 | 20 | 57 | | 2003 | 37 | 20 | 57 | | 2004 | 46 | 24 | 70 | | 2005 | 30 | 33 | 63 | | 2006 | 24 | 24 | 48 | | 2007 | 21 | 10 | 31 | | 2008 | 22 | 22 | 44 | | 2009 | 20 | 24 | 44 | | 2010 | 16 | 23 | 39 | | 2011 | 20 | 21 | 41 | | 2012 | 25 | 30 | 55 | | 2013 | 33 | 23 | 56 | | 2014 | 27 | 23 | 50 | | 2015 | 14 | 24 | 38 | | 2016 | 30 | 25 | 55 | | 2017 | 30 | 23 | 53 | | 2018 | 24 | 20 | 44 | | 2019 | 22 | 19 | 41 | | 2020 | 17 | 25 | 42 | | 2021 | 18 | 19 | 37 | | 2022 | 10 | 39 | 49 | | 2023 | 6 | 30 | 36 | | 2024 | 7 | 14 | 21 | | 2025 | 14 | 5 | 19 |
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Below are the most recent publications written about "Transcription Factors" by people in Profiles.
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Palacio M, Taatjes DJ. Real-time visualization of reconstituted transcription reveals RNAPII activation mechanisms at single promoters. Cell Rep. 2025 Sep 23; 44(9):116251.
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Zhou X, Moreira S, Restelli C, Wang H, Jahangiri S, Aryal S, Tsao E, Zhang P, Niu M, Kumar H, Balde Z, Vujovic A, Liu L, Wong N, Arruda A, Minden MD, Zhou Y, Ravi B, Qi J, Li C, Hope KJ, Lu R. Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models. Sci Transl Med. 2025 Aug 06; 17(810):eadn5400.
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Wagner DE, Alsafadi HN, Mitash N, Justet A, Hu Q, Pineda R, Staab-Weijnitz C, Korfei M, Gvazava N, Wannemo K, Onwuka U, Mozurak M, Estrada-Bernal A, Cala-Garcia J, Mutze K, Costa R, Bölükbas D, Stegmayr J, Skronska-Wasek W, Klee S, Ota C, Baarsma HA, Wang J, Sembrat J, Hilgendorff A, Ding J, Günther A, Chambers R, Rosas I, de Langhe S, Kaminski N, Lehmann M, Eickelberg O, Königshoff M. Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models. Nat Commun. 2025 Aug 02; 16(1):7099.
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Chan YS, Gao Q, Robinson SA, Wang W, Filandrova R, Weinhold LM, Cabrera ML, Zhang M, Ambati CSR, Lerario AM, Putluri N, Kiseljak-Vassiliades K, Wierman ME, Habra MA, Hammer GD, Veverka V, Cermakova K, Hodges HC. ß-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
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Guo XS, Khalifa A, Selvam K, Kutateladze TG, Liu WR. Development of Chemical Tools for the Human YEATS Domain. ACS Chem Biol. 2025 Aug 15; 20(8):1828-1840.
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Becht DC, Biswas S, Xu C, Xuan H, Khalil M, Cai L, Musselman CA, Liu X, Affar EB, Shi X, Wang GG, Kutateladze TG. Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300. Biochem J. 2025 Jul 02; 482(13):955-968.
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Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM. Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. Nat Commun. 2025 Jun 10; 16(1):5136.
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Strong A, McKenna C, Stals K, Vitobello A, Renaud M, Rieubland C, Guipponi M, Philippe C, Vrana P, Gaskell A, Innes AM, Rippert AL, Ahrens-Nicklas R, Bhoj E, Keller K, Chaudhari BP, Stone BS. Truncating Variants in RREB1 Cause a Novel RASopathy Syndrome of Congenital Heart Disease, Genitourinary Malformations, and Developmental Delay. Am J Med Genet A. 2025 Oct; 197(10):e64119.
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Sargen MR, Fitzhugh MH, Ko JS, Close AG, Horton SC, Malik F, Furtado LV, Bahrami A, Seynnaeve BKN, Pappo AS, Liu V, Cheung K, Pack SD, Xi L, Raffeld M, Lee I, Gagan J, Aldape K, Barr FG, Hewitt SM, Ferrone CK, Hayden A, Hatton JN, Goldstein AM, Pfeiffer RM, Widemann B, Malone MFW, Gross AM, Kaplan R, Yohe ME, Berrebi KG. Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series. Pediatr Blood Cancer. 2025 Aug; 72(8):e31814.
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Nagel M, Taatjes DJ. Regulation of RNA polymerase II transcription through re-initiation and bursting. Mol Cell. 2025 May 15; 85(10):1907-1919.
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