 Autophagy
"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
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| MeSH Number(s) |
G04.146.399 G04.417.350.091
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| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
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Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 2 | 4 | | 2010 | 1 | 1 | 2 | | 2011 | 4 | 2 | 6 | | 2012 | 5 | 3 | 8 | | 2013 | 11 | 6 | 17 | | 2014 | 15 | 6 | 21 | | 2015 | 2 | 3 | 5 | | 2016 | 9 | 3 | 12 | | 2017 | 7 | 5 | 12 | | 2018 | 8 | 3 | 11 | | 2019 | 9 | 6 | 15 | | 2020 | 4 | 4 | 8 | | 2021 | 5 | 2 | 7 | | 2022 | 2 | 6 | 8 | | 2023 | 0 | 5 | 5 | | 2024 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Autophagy" by people in Profiles.
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Villagomez FR, Lang J, Rosario FJ, Nunez-Avellaneda D, Webb P, Neville M, Woodruff ER, Bitler BG. Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei. Cancer Res Commun. 2024 Jul 01; 4(7):1625-1642.
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Martin TG, Pak H, Gerhard GS, Merali S, Merali C, Lemster B, Dubey P, McTiernan CF, Bristow MR, Feldman AM, Kirk JA. Dysregulated Autophagy and Sarcomere Dysfunction in Patients With Heart Failure With Co-Occurrence of P63A and P380S BAG3 Variants. J Am Heart Assoc. 2023 12 19; 12(24):e029938.
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Bunker EN, Le Guerrou? F, Wang C, Strub MP, Werner A, Tjandra N, Youle RJ. Nix interacts with WIPI2 to induce mitophagy. EMBO J. 2023 Nov 15; 42(22):e113491.
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Alula KM, Theiss AL. Autophagy in Crohn's Disease: Converging on Dysfunctional Innate Immunity. Cells. 2023 07 04; 12(13).
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Le Guerrou? F, Bunker EN, Rosencrans WM, Nguyen JT, Basar MA, Werner A, Chou TF, Wang C, Youle RJ. TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1. Mol Cell. 2023 03 16; 83(6):927-941.e8.
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Nassour J, Aguiar LG, Correia A, Schmidt TT, Mainz L, Przetocka S, Haggblom C, Tadepalle N, Williams A, Shokhirev MN, Akincilar SC, Tergaonkar V, Shadel GS, Karlseder J. Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis. Nature. 2023 02; 614(7949):767-773.
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Bhatt V, Lan T, Wang W, Kong J, Lopes EC, Wang J, Khayati K, Raju A, Rangel M, Lopez E, Hu ZS, Luo X, Su X, Malhotra J, Hu W, Pine SR, White E, Guo JY. Inhibition of autophagy and MEK promotes ferroptosis in Lkb1-deficient Kras-driven lung tumors. Cell Death Dis. 2023 01 26; 14(1):61.
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Alula KM, Delgado-Deida Y, Callahan R, Till A, Underwood L, Thompson WE, Souza RF, Dassopoulos T, Onyiah J, Venuprasad K, Theiss AL. Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy. Sci Rep. 2023 01 02; 13(1):18.
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Shearn CT, Anderson AL, Devereux MW, Orlicky DJ, Michel C, Petersen DR, Miller CG, Harpavat S, Schmidt EE, Sokol RJ. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS One. 2022; 17(11):e0276879.
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Koschade SE, Klann K, Shaid S, Vick B, Stratmann JA, Th?lken M, Meyer LM, Nguyen TD, Campe J, Moser LM, Hock S, Baker F, Meyer CT, Wempe F, Serve H, Ullrich E, Jeremias I, M?nch C, Brandts CH. Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia. Leukemia. 2022 10; 36(10):2396-2407.
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