 Intracellular Signaling Peptides and Proteins
"Intracellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.
| Descriptor ID |
D047908
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| MeSH Number(s) |
D12.644.360 D12.776.476
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Intracellular Signaling Peptides and Proteins".
Below are MeSH descriptors whose meaning is more specific than "Intracellular Signaling Peptides and Proteins".
This graph shows the total number of publications written about "Intracellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intracellular Signaling Peptides and Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 6 | 6 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 7 | 8 | | 2002 | 3 | 4 | 7 | | 2003 | 2 | 9 | 11 | | 2004 | 1 | 13 | 14 | | 2005 | 4 | 14 | 18 | | 2006 | 9 | 13 | 22 | | 2007 | 6 | 7 | 13 | | 2008 | 8 | 4 | 12 | | 2009 | 11 | 6 | 17 | | 2010 | 9 | 10 | 19 | | 2011 | 5 | 8 | 13 | | 2012 | 10 | 5 | 15 | | 2013 | 9 | 5 | 14 | | 2014 | 7 | 6 | 13 | | 2015 | 12 | 12 | 24 | | 2016 | 4 | 3 | 7 | | 2017 | 7 | 7 | 14 | | 2018 | 6 | 3 | 9 | | 2019 | 8 | 7 | 15 | | 2020 | 4 | 8 | 12 | | 2021 | 7 | 3 | 10 | | 2022 | 2 | 6 | 8 | | 2023 | 0 | 5 | 5 | | 2024 | 2 | 5 | 7 | | 2025 | 6 | 2 | 8 | | 2026 | 3 | 2 | 5 |
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Below are the most recent publications written about "Intracellular Signaling Peptides and Proteins" by people in Profiles.
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Cain P, Milstead R, Griffioen M, Wong H, Borski C, Cooper-Sansone A, LaPlante L, Kastengren K, Cotto S, Hanson J, Freigassner B, Link C, Opp M, Hoeffer C. Restoring RCAN1 dosage mitigates sleep and EEG abnormalities in a Down syndrome model. Neurobiol Dis. 2026 06 01; 223:107375.
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Sripada A, Varma R, Sirohi K, Sahu A, Verma M, Alam R. Sprouty2 modulates NF-?B signaling by sequestering the phosphatase PP2Ac in LPS-stimulated macrophages. J Immunol. 2026 Mar 17; 215(3).
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Zhu W, Pan L, Cui X, Russo AC, Ray R, Pederson B, Wei X, Lin LL, Torres M, Hafner H, Gregg B, Shrestha N, Liu C, Naji A, Arvan P, Sandoval DA, Lindberg I, Qi L, Reinert RB. SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet a cells. Nat Commun. 2026 Feb 25; 17(1).
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Nelson CB, Wells JK, Kesarwani E, Sobinoff AP, Fernando M, Gao J, MacKenzie KL, Poulos RC, Nawaz U, Wang X, Ford HL, Pickett HA. Potent synthetic lethality between PLK1 and EYA family inhibitors in tumors of the central and peripheral nervous systems. Genes Dev. 2026 02 02; 40(3-4):267-283.
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Clayfield L, Malik D, Whittle J, Xu J, Mevel R, Fadlullah MZH, Patel R, Szpakowska M, Maqbool MA, Jones M, Lie-A-Ling M, Chevigne A, Paggetti J, Moussay E, Baker SM, Iqbal M, Maire P, Somervaille TCP, Ford HL, Kouskoff V, Largeot A, Lacaud G. Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia. Cell Rep. 2026 Feb 24; 45(2):116875.
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Nassar AH, Kim C, Adeyelu T, Bou Farhat E, Abushukair H, Rakaee M, Matteson K, Lau SF, Takabe Y, Ocejo A, Ardeshir-Larijani F, Leal T, Ramalingam S, Alam S, Gray JE, Hicks J, Kaldas D, Baena J, Berjaga MZ, Nana FA, Grohe C, Leuders H, Citarella F, Cortellini A, Mingo EC, Pancirer D, Das M, Ellis-Caleo TJ, Cheung JM, Lin JJ, Watson AS, Camidge DR, Sridhar A, Parikh K, Crowley F, Marron TU, Aggarwal V, Ahmed M, Sankar K, Kawtharany H, Zhang J, Owen DH, Li M, Nagasaka M, Pinato DJ, Awosika N, Alhamad K, Puri S, Zaman U, Gupta DM, Lau C, Khan H, Liauw J, Velazquez AI, Brown T, Moliner L, Mosteiro M, Rocha P, Evans M, Vanderwalde A, Elliott A, Nieva J, Lopes G, Ma PC, Borghaei H, Lee M, Young L, Aljumaily R, Mirza H, Kwiatkowski DJ, Herbst RS, Flavell RA, Naqash AR, Chiang AC. Integrated molecular and clinical characterization of pulmonary large cell neuroendocrine carcinoma. Nat Commun. 2025 Aug 19; 16(1):7717.
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Nouri HR, Schaunaman N, Kraft M, Numata M, Vercelli D, Chu HW. Tollip deficiency enhances mitophagy and reduces STING activation in influenza A virus-infected mice. J Immunol. 2025 Jul 01; 214(7):1741-1753.
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Lee GY, Schaunaman N, Nouri HR, Kraft M, Chu HW. Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells. BMC Res Notes. 2025 Apr 23; 18(1):194.
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Lippincott MJ, Tomkinson J, Bunten D, Mohammadi M, Kastl J, Knop J, Schwandner R, Huang J, Ongo G, Robichaud N, Dagher M, Mansilla-Soto A, Saravia-Estrada C, Tsuboi M, Basualto-Alarcón C, Way GP. A morphology and secretome map of pyroptosis. Mol Biol Cell. 2025 Jun 01; 36(6):ar63.
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Nunes LGA, Weingrill RB, Fredrick SBJ, Lorca R, Lee MJ, Atif SM, Chicco AJ, Rosario FJ, Urschitz J. Trophoblast-specific Deptor knockdown enhances trophoblast nutrient transport and fetal growth in mice. Acta Physiol (Oxf). 2025 Apr; 241(4):e70012.
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