 T-Lymphocytes
"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
| Descriptor ID |
D013601
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| MeSH Number(s) |
A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
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| Concept/Terms |
T-Lymphocytes- T-Lymphocytes
- T Lymphocytes
- T-Lymphocyte
- T-Cells
- T Cells
- T-Cell
- Thymus-Dependent Lymphocytes
- Lymphocyte, Thymus-Dependent
- Lymphocytes, Thymus-Dependent
- Thymus Dependent Lymphocytes
- Thymus-Dependent Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".
This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 11 | 17 | | 1996 | 11 | 8 | 19 | | 1997 | 20 | 5 | 25 | | 1998 | 21 | 8 | 29 | | 1999 | 18 | 6 | 24 | | 2000 | 22 | 7 | 29 | | 2001 | 22 | 9 | 31 | | 2002 | 20 | 13 | 33 | | 2003 | 20 | 11 | 31 | | 2004 | 21 | 14 | 35 | | 2005 | 26 | 8 | 34 | | 2006 | 21 | 15 | 36 | | 2007 | 17 | 10 | 27 | | 2008 | 16 | 15 | 31 | | 2009 | 21 | 13 | 34 | | 2010 | 15 | 13 | 28 | | 2011 | 11 | 20 | 31 | | 2012 | 14 | 12 | 26 | | 2013 | 32 | 15 | 47 | | 2014 | 21 | 11 | 32 | | 2015 | 20 | 14 | 34 | | 2016 | 20 | 7 | 27 | | 2017 | 20 | 12 | 32 | | 2018 | 20 | 20 | 40 | | 2019 | 22 | 21 | 43 | | 2020 | 21 | 24 | 45 | | 2021 | 22 | 24 | 46 | | 2022 | 10 | 19 | 29 | | 2023 | 4 | 21 | 25 | | 2024 | 11 | 22 | 33 | | 2025 | 6 | 2 | 8 |
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Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.
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Hohenstein AC, Gallegos JB, Dang M, Groegler J, Broncucia H, Tensun FA, Waugh K, Dong F, James EA, Speake C, Steck AK, Rewers MJ, Gottlieb PA, Haskins K, Delong T, Baker RL. Novel T-Cell Reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Individuals. Diabetes. 2025 Jun 01; 74(6):933-942.
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Fry TJ. The Paradox of Acute Myeloid Leukemia Responsiveness to Adoptive T-cell Therapy. Blood Cancer Discov. 2025 May 05; 6(3):157-158.
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Pham-Danis C, Novak AJ, Danis E, McClellan SM, Leach L, Yarnell MC, Ebmeier CC, Tasian SK, Kohler ME. Restoration of LAT activity improves CAR T?cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia. Cancer Cell. 2025 Mar 10; 43(3):482-502.e9.
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Hilliard BK, Prendergast JE, Smith MJ. Dia-B-Ties: B Cells in the Islet-Immune-Cell Interface in T1D. Biomolecules. 2025 Feb 25; 15(3).
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Porazzi P, Nason S, Yang Z, Carturan A, Ghilardi G, Guruprasad P, Patel RP, Tan M, Padmanabhan AA, Lemoine J, Fardella E, Zhang Y, Pajarillo R, Chen L, Ugwuanyi O, Markowitz K, Delman D, Angelos MG, Shestova O, Isshiki Y, Blanchard T, B?guelin W, Melnick AM, Linette GP, Beatty GL, Carreno BM, Cohen IJ, Paruzzo L, Schuster SJ, Ruella M. EZH1/EZH2 inhibition enhances adoptive T?cell immunotherapy against multiple cancer models. Cancer Cell. 2025 Mar 10; 43(3):537-551.e7.
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Battram AM, Ma??-Pujol J, Moreno DF, Oliver-Cald?s A, Carpio J, Cardus O, Rodr?guez-Lobato LG, Urbano-Ispizua ?, Fern?ndez de Larrea C. Genetic disruption of Blimp-1 drastically augments the antitumor efficacy of BCMA-targeting CAR T cells. Blood Adv. 2025 Feb 11; 9(3):627-641.
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Jha V, Freed BM, Sunderhaus ER, Lee JE, Prage EB, Miglani M, Rosloniec EF, Matsuda JL, Coulombe MG, McKee AS, Roark CL. Substitution of Glutamic Acid at Position 71 of DR?1*04:01 and Collagen-Specific Tolerance Without Alloreactivity. Arthritis Rheumatol. 2025 May; 77(5):526-535.
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Borgers JSW, Lenkala D, Kohler V, Jackson EK, Linssen MD, Hymson S, McCarthy B, O'Reilly Cosgrove E, Balogh KN, Esaulova E, Starr K, Ware Y, Klobuch S, Sciuto T, Chen X, Mahimkar G, Sheen JHF, Ramesh S, Wilgenhof S, van Thienen JV, Scheiner KC, Jedema I, Rooney M, Dong JZ, Srouji JR, Juneja VR, Arieta CM, Nuijen B, Gottstein C, Finney OC, Manson K, Nijenhuis CM, Gaynor RB, DeMario M, Haanen JB, van Buuren MM. Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial. Nat Med. 2025 Mar; 31(3):881-893.
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Waibl Polania J, Hoyt-Miggelbrink A, Tomaszewski WH, Wachsmuth LP, Lorrey SJ, Wilkinson DS, Lerner E, Woroniecka K, Finlay JB, Ayasoufi K, Fecci PE. Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion. Immunity. 2025 Jan 14; 58(1):232-246.e6.
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Eljilany I, Coleman S, Tan AC, McCarter MD, Carpten J, Colman H, Naqash AR, Puzanov I, Arnold SM, Churchman ML, Spakowicz D, Salhia B, Marin J, Ganesan S, Ratan A, Shriver C, Hwu P, Dalton WS, Weiner GJ, Conejo-Garcia JR, Rodriguez P, Tarhini AA. Differential Infiltration of Key Immune T-Cell Populations Across Malignancies Varying by Immunogenic Potential and the Likelihood of Response to Immunotherapy. Cells. 2024 12 03; 13(23).
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