 T-Lymphocytes
"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
| Descriptor ID |
D013601
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| MeSH Number(s) |
A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
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| Concept/Terms |
T-Lymphocytes- T-Lymphocytes
- T Lymphocytes
- T-Lymphocyte
- T-Cells
- T Cells
- T-Cell
- Thymus-Dependent Lymphocytes
- Lymphocyte, Thymus-Dependent
- Lymphocytes, Thymus-Dependent
- Thymus Dependent Lymphocytes
- Thymus-Dependent Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".
This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 12 | 8 | 20 | | 1997 | 20 | 6 | 26 | | 1998 | 21 | 8 | 29 | | 1999 | 19 | 6 | 25 | | 2000 | 22 | 5 | 27 | | 2001 | 23 | 9 | 32 | | 2002 | 20 | 13 | 33 | | 2003 | 20 | 11 | 31 | | 2004 | 23 | 15 | 38 | | 2005 | 28 | 8 | 36 | | 2006 | 22 | 14 | 36 | | 2007 | 17 | 10 | 27 | | 2008 | 18 | 16 | 34 | | 2009 | 23 | 14 | 37 | | 2010 | 16 | 15 | 31 | | 2011 | 11 | 22 | 33 | | 2012 | 15 | 12 | 27 | | 2013 | 33 | 15 | 48 | | 2014 | 21 | 13 | 34 | | 2015 | 21 | 14 | 35 | | 2016 | 20 | 7 | 27 | | 2017 | 19 | 16 | 35 | | 2018 | 23 | 27 | 50 | | 2019 | 24 | 23 | 47 | | 2020 | 25 | 22 | 47 | | 2021 | 24 | 28 | 52 | | 2022 | 10 | 21 | 31 | | 2023 | 4 | 29 | 33 | | 2024 | 12 | 29 | 41 | | 2025 | 25 | 5 | 30 | | 2026 | 9 | 7 | 16 |
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Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.
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Magno JC, Guo J, Hall SC, Liu J, Albert GK, Carter JD, Davalos AS, Cao P, Bangar A, Drigot Z, Hudson H, Geluck T, Nevala WK, Markovic SN, Wilky BA, Davila E. Engineering T Cells with a Tumor-Reactive Chimeric T-cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses. Cancer Res. 2026 Jun 01; 86(11):2688-2702.
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Kendirli PK, Erdem S, Kisaarslan AP, Gök V, Kayhan E, Özcan A, Dogan ME, Klein C, Ünal E, Eken A. A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP). Inflamm Res. 2026 May 19; 75(1).
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Lee J, Chung YM, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026 May; 653(8116):1184-1195.
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Eken A, Johnson SA, Erdem S, Hsieh EWY. LCK'ed in: Inborn errors of immunity in LCK reveal how TCR signaling is calibrated. J Exp Med. 2026 May 04; 223(6).
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Duffy JT, Martin-Regalado A, Haupt BE, Pogue JR, Thakur A, Cota MF, Zannikou M, Misener S, Krymskaya VP, McCortney K, Miska J, Horbinski C, Simberg D, Lesniak MS, James CD, Stupp R, Balyasnikova IV. Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors. Adv Sci (Weinh). 2026 Jun; 13(35):e22391.
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Gattinoni L, Inchingolo G, Harrer DC, Susana A, Puccio S, Slavkovic-Lukic D, Natrakul DA, Strieder N, Heuser-Loy C, Baldwin JG, Fioravanti J, Ji Y, Gautam S, Suriano C, Martín-Santos A, Schelker RC, Patel N, Mann J, Goff S, Mikkilineni L, Yang JC, Kwong MLM, Patel R, Rehli M, Highfill SL, Stroncek DF, Rosenberg SA, Biasco L, Lugli E, Brudno JN, Kochenderfer JN. Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse. Cell. 2026 Jun 11; 189(12):3686-3700.e10.
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Garza B, Calhoun J, Norman PJ, Cline N, Kichula KM, Farias TDJ, Sams S, Boorgula MP, Danhorn T, Haugen BR, French JD. Tumor-infiltrating T Lymphocytes Recognize Thyroid-specific Proteins and Neo-antigens in Follicular Cell-derived Thyroid Cancers. J Clin Endocrinol Metab. 2026 Apr 22; 111(5):e1289-e1301.
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Kim D, Moon SJ, Han EL, Feng E, Murray AM, Wang J, Liu W, Kong G, June CH, Mitchell MJ. HITE: HIV Inspired Lipid Nanoparticle Platform for CAR T Cell Engineering. Nano Lett. 2026 May 06; 26(17):5668-5679.
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Carturan A, Angelos MG, Guruprasad P, Patel RP, Pajarillo R, Lee A, Espie D, Zhang Y, Chiang YH, Xie W, Rodriguez JL, Harris J, Devi P, Afolayan-Oloye OI, Xu J, Sussman JH, Elghawy O, Yang A, Barsouk A, Cho JH, Shaw CE, Singh E, Ugwuanyi O, Paruzzo L, Stella F, Liu S, Nason S, Imparato A, Rotolo A, Lemoine J, Barrett DM, Posey A, Rook AH, Pillai V, Bagg A, Pileri SA, Liu D, Tan K, Schuster SJ, Teachey DT, Porazzi P, Ruella M. Harnessing the CD2 axis to broaden and enhance the efficacy of CAR T-cell therapies. Blood. 2026 Apr 16; 147(16):1842-1856.
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Milanesi S, Lorenzini T, Marchetti T, Tintor D, Planas R, Sabet O, Malmström L, Acharya S, Williams CD, Manning ZE, Roser JH, Ehler AC, Huber M, Prader S, Vavassori S, Dutmer CM, Abbott JK, Pachlopnik Schmid J. Variants in human CD48 lead to impaired T cell immunity and increased inflammation. J Clin Invest. 2026 06 01; 136(11).
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