T-Lymphocytes
"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
| Descriptor ID |
D013601
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| MeSH Number(s) |
A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
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| Concept/Terms |
T-Lymphocytes- T-Lymphocytes
- T Lymphocytes
- T-Lymphocyte
- T-Cells
- T Cells
- T-Cell
- Thymus-Dependent Lymphocytes
- Lymphocyte, Thymus-Dependent
- Lymphocytes, Thymus-Dependent
- Thymus Dependent Lymphocytes
- Thymus-Dependent Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".
This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 11 | 17 | | 1996 | 12 | 8 | 20 | | 1997 | 20 | 5 | 25 | | 1998 | 21 | 8 | 29 | | 1999 | 18 | 6 | 24 | | 2000 | 22 | 7 | 29 | | 2001 | 23 | 9 | 32 | | 2002 | 21 | 13 | 34 | | 2003 | 20 | 11 | 31 | | 2004 | 22 | 16 | 38 | | 2005 | 27 | 8 | 35 | | 2006 | 22 | 16 | 38 | | 2007 | 18 | 11 | 29 | | 2008 | 18 | 16 | 34 | | 2009 | 23 | 14 | 37 | | 2010 | 16 | 15 | 31 | | 2011 | 11 | 21 | 32 | | 2012 | 16 | 12 | 28 | | 2013 | 33 | 15 | 48 | | 2014 | 20 | 11 | 31 | | 2015 | 21 | 15 | 36 | | 2016 | 20 | 7 | 27 | | 2017 | 20 | 13 | 33 | | 2018 | 23 | 22 | 45 | | 2019 | 24 | 23 | 47 | | 2020 | 25 | 24 | 49 | | 2021 | 23 | 28 | 51 | | 2022 | 10 | 21 | 31 | | 2023 | 4 | 28 | 32 | | 2024 | 12 | 27 | 39 | | 2025 | 12 | 3 | 15 |
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Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.
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He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Ferrannini AC, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen KH, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation. Sci Transl Med. 2025 Sep 24; 17(817):eadt7214.
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Rodríguez-Lobato LG, Cardús O, Mañé-Pujol J, Battram AM, Vaqué-Salsench S, Carpio J, Pérez-Amill L, Calderón H, Martín-Antonio B, Oliver-Caldés A, Lozano E, Moreno DF, Ortiz-Maldonado V, Salas MQ, de Daniel A, Tovar N, Cibeira MT, Rosiñol L, Bladé J, Juan M, Urbano-Ispizua Á, Engel P, Fernández de Larrea C. Bicistronic CAR T Cell against BCMA and CD229 Effectively Controls Myeloma Even When BCMA Expression Is Limited. Cancer Immunol Res. 2025 Sep 02; 13(9):1374-1390.
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Smith MJ, Boldison J, Wong FS. The Role of B Lymphocytes in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2025 Sep 02; 15(9).
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Baum HE, Santopaolo M, Francis O, Milodowski EJ, Entwistle K, Oliver E, Hitchings B, Diamond D, Thomas AC, Mitchell RE, Kibble M, Gupta K, Di Bartolo N, Klenerman P, Brown A, Morales-Aza B, Oliver J, Berger I, Toye AM, Finn A, Goenka A, Davidson AD, Ring S, Molloy L, Lewcock M, Northstone K, Roth F, Timpson NJ, Wooldridge L, Halliday A, Rivino L. Hybrid B- and T-Cell Immunity Associates With Protection Against Breakthrough Infection After Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination in Avon Longitudinal Study of Parents and Children (ALSPAC) Participants. J Infect Dis. 2025 Aug 14; 232(2):e327-e340.
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Feng Y, Haupt B, Huynh TT, Meshaw R, Martin-Regalado A, Thakur A, Duffy JT, Alzeer A, Siegel DA, Barnes A, Simberg D, Zalutsky MR, Balyasnikova IV. Longitudinal Imaging Reveals Tumor Uptake and Prolonged Retention of Bispecific T Cell-Engaging Antibody in GBM via Passive and Active Mechanisms. Clin Cancer Res. 2025 Aug 14; 31(16):3537-3549.
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Thite NG, Yarnell M, Fry TJ, Seefeldt M, Calderon CP, Randolph TW. Unsupervised Machine Learning-Based Process Analytical Tools for Near Real-Time Cell Morphology Analysis During CAR-T Cell Manufacturing. Biotechnol Bioeng. 2025 Sep; 122(9):2377-2388.
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Hohenstein AC, Gallegos JB, Dang M, Groegler J, Broncucia H, Tensun FA, Waugh K, Dong F, James EA, Speake C, Steck AK, Rewers MJ, Gottlieb PA, Haskins K, Delong T, Baker RL. Novel T-Cell Reactivities to Hybrid Insulin Peptides in Islet Autoantibody-Positive At-Risk Individuals. Diabetes. 2025 Jun 01; 74(6):933-942.
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Teles LN, Beatty LA, Hernandez AV, Mendoza MA, Wilkes ZM, Dominick VP, Argy Telias MT, Miller B, Huang CY, Bechi Genzano C, Andreopoulos FM, Dauer EA, Creusot RJ, Tomei AA. Engineered macroporous gelatin scaffolds enhance lymph node fibroblastic reticular cell identity and enable diabetogenic T cell immunomodulation. Biomaterials. 2026 Jan; 324:123460.
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Fry TJ. The Paradox of Acute Myeloid Leukemia Responsiveness to Adoptive T-cell Therapy. Blood Cancer Discov. 2025 May 05; 6(3):157-158.
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Pham-Danis C, Novak AJ, Danis E, McClellan SM, Leach L, Yarnell MC, Ebmeier CC, Tasian SK, Kohler ME. Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia. Cancer Cell. 2025 Mar 10; 43(3):482-502.e9.
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