 Gene Regulatory Networks
"Gene Regulatory Networks" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
| Descriptor ID |
D053263
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| MeSH Number(s) |
G05.360.080.689.360
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| Concept/Terms |
Gene Regulatory Networks- Gene Regulatory Networks
- Gene Regulatory Network
- Network, Gene Regulatory
- Networks, Gene Regulatory
- Regulatory Network, Gene
- Regulatory Networks, Gene
- Gene Networks
- Gene Network
- Network, Gene
- Networks, Gene
- Transcriptional Networks
- Network, Transcriptional
- Networks, Transcriptional
- Transcriptional Network
Gene Circuits- Gene Circuits
- Circuit, Gene
- Circuits, Gene
- Gene Circuit
Gene Modules- Gene Modules
- Module, Gene
- Modules, Gene
- Gene Module
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Below are MeSH descriptors whose meaning is more general than "Gene Regulatory Networks".
Below are MeSH descriptors whose meaning is more specific than "Gene Regulatory Networks".
This graph shows the total number of publications written about "Gene Regulatory Networks" by people in this website by year, and whether "Gene Regulatory Networks" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 4 | 5 | | 2008 | 1 | 1 | 2 | | 2009 | 5 | 3 | 8 | | 2010 | 0 | 7 | 7 | | 2011 | 2 | 2 | 4 | | 2012 | 4 | 4 | 8 | | 2013 | 7 | 10 | 17 | | 2014 | 4 | 11 | 15 | | 2015 | 6 | 4 | 10 | | 2016 | 8 | 9 | 17 | | 2017 | 8 | 20 | 28 | | 2018 | 7 | 11 | 18 | | 2019 | 4 | 10 | 14 | | 2020 | 6 | 9 | 15 | | 2021 | 4 | 6 | 10 | | 2022 | 1 | 5 | 6 | | 2023 | 0 | 7 | 7 | | 2024 | 4 | 9 | 13 | | 2025 | 6 | 7 | 13 | | 2026 | 3 | 2 | 5 |
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Below are the most recent publications written about "Gene Regulatory Networks" by people in Profiles.
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Nair V, Minakawa A, Smith C, Berthier CC, Hartman J, Menon R, Fermin D, Otto EA, Gisch DL, Eadon MT, Jain S, Choi YJ, Pyle L, Eichinger F, Alakwaa FM, Rose MP, Subramanian L, El Saghir J, Beamish JA, Hodgin JB, Brosius FC, Bjornstad P, Nelson PJ, Harder JL, Werner T, Kretzler M, Schaub JA. Hypoxia inducible factor network reflects kidney disease progression in diabetes and sodium-glucose co-transporters inhibition. Signal Transduct Target Ther. 2026 Apr 21; 11(1).
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Purvis IJ, Ochoa Olmos OE, Park KU, Kaufman ML, Henry CM, Schaaf C, Clise OJ, Tesdahl CD, Haas A, Brzezinski JA. A robust cis-regulatory network ensures Otx2 expression during retinal development. Development. 2026 Mar 15; 153(6).
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Lazarevic S, Perez-Cervantes C, Wang Z, Shen KM, Gadek M, Xiao J, Yamaguchi N, Hall JM, Koca Y, Chapski DJ, Rosa-Garrido M, Rubino M, Nadadur RD, McKinsey TA, Vondriska TM, Ruthenburg AJ, Pott S, Park DS, Moskowitz IP. A reduced TBX5-dependent gene regulatory network links atrial fibrillation and heart failure. Nat Cardiovasc Res. 2026 Feb; 5(2):96-117.
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Clayfield L, Malik D, Whittle J, Xu J, Mevel R, Fadlullah MZH, Patel R, Szpakowska M, Maqbool MA, Jones M, Lie-A-Ling M, Chevigne A, Paggetti J, Moussay E, Baker SM, Iqbal M, Maire P, Somervaille TCP, Ford HL, Kouskoff V, Largeot A, Lacaud G. Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia. Cell Rep. 2026 Feb 24; 45(2):116875.
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Arena KA, Kearns CA, Ahmed M, O'Rourke R, Sagerström CG, Franco SJ, Appel B. Gsx2 regulates oligodendrocyte precursor formation in the zebrafish spinal cord. Dev Biol. 2026 Mar; 531:30-44.
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Yuan H, Mancuso CA, Johnson K, Braasch I, Krishnan A. Computational strategies for cross-species knowledge transfer. Nat Methods. 2026 Feb; 23(2):312-327.
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Pavelka J, Voong CK, Schaal P, Lam MPY, Lau E. SALVE: prediction of interorgan communication with transcriptome latent space representation. Am J Physiol Heart Circ Physiol. 2025 Dec 01; 329(6):H1621-H1632.
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Ozekin YH, O'Rourke R, Bates EA. Kcnj2 regulates electrical activity-induced gene networks in embryonic mouse palate shelves. Dev Biol. 2025 Nov; 527:260-274.
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Avila JA, Benthal JT, Schafer JC, Flaherty DK, Southard-Smith EM. Single Cell Profiling in the Sox10Dom Hirschsprung Mouse Implicates Hox Genes in Enteric Neuron Trajectory Allocation. Cell Mol Gastroenterol Hepatol. 2025; 19(12):101590.
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Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM. Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC. Nat Commun. 2025 Jun 10; 16(1):5136.
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