 Ketocholesterols
"Ketocholesterols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cholesterol substituted in any position by a keto moiety. The 7-keto isomer inhibits cholesterol uptake in the coronary arteries and aorta by blocking 3-hydroxy-3-methylglutaryl-CoA reductase activity.
| Descriptor ID |
D007653
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| MeSH Number(s) |
D04.210.500.247.222.265.450 D04.210.500.247.222.284.800.750 D04.210.500.247.808.197.800.750 D10.570.938.208.825.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketocholesterols".
Below are MeSH descriptors whose meaning is more specific than "Ketocholesterols".
This graph shows the total number of publications written about "Ketocholesterols" by people in this website by year, and whether "Ketocholesterols" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketocholesterols" by people in Profiles.
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Willard KA, Elling CL, Stice SL, Brindley MA. The Oxysterol 7-Ketocholesterol Reduces Zika Virus Titers in Vero Cells and Human Neurons. Viruses. 2018 12 30; 11(1).
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Miyazaki-Anzai S, Masuda M, Demos-Davies KM, Keenan AL, Saunders SJ, Masuda R, Jablonski K, Cavasin MA, Kendrick J, Chonchol M, McKinsey TA, Levi M, Miyazaki M. Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification. J Am Heart Assoc. 2014 Jun 24; 3(3):e000949.
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Li W, Laskar A, Sultana N, Osman E, Ghosh M, Li Q, Yuan XM. Cell death induced by 7-oxysterols via lysosomal and mitochondrial pathways is p53-dependent. Free Radic Biol Med. 2012 Dec 01; 53(11):2054-61.
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King SR, Matassa AA, White EK, Walsh LP, Jo Y, Rao RM, Stocco DM, Reyland ME. Oxysterols regulate expression of the steroidogenic acute regulatory protein. J Mol Endocrinol. 2004 Apr; 32(2):507-17.
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Liu Q, Kobayashi K, Furukawa J, Inagaki J, Sakairi N, Iwado A, Yasuda T, Koike T, Voelker DR, Matsuura E. Omega-carboxyl variants of 7-ketocholesteryl esters are ligands for beta(2)-glycoprotein I and mediate antibody-dependent uptake of oxidized LDL by macrophages. J Lipid Res. 2002 Sep; 43(9):1486-95.
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