 Serine
"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
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| MeSH Number(s) |
D12.125.154.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 | | 1996 | 3 | 2 | 5 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 3 | 4 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 2 | 3 | | 2001 | 1 | 2 | 3 | | 2002 | 1 | 2 | 3 | | 2003 | 0 | 5 | 5 | | 2004 | 0 | 2 | 2 | | 2005 | 2 | 3 | 5 | | 2006 | 1 | 6 | 7 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 6 | 7 | | 2009 | 1 | 4 | 5 | | 2010 | 1 | 4 | 5 | | 2011 | 0 | 3 | 3 | | 2012 | 1 | 4 | 5 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 5 | 5 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 1 | 3 | | 2022 | 1 | 5 | 6 | | 2023 | 1 | 2 | 3 | | 2024 | 0 | 3 | 3 | | 2025 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Serine" by people in Profiles.
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Trujillo MN, Jennings EQ, Farrera DO, Kitamura N, Anderson CC, Gehrke S, Reisz JA, Johannsen M, Roede JR, D'Alessandro A, Galligan JJ. Glyoxalase 2 Coordinates de Novo Serine Metabolism. Chembiochem. 2025 Apr 01; 26(7):e202401086.
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Roychowdhury T, McNutt SW, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, De Stanchina E, Corben A, Modi S, Alpaugh ML, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation. Nat Commun. 2024 10 16; 15(1):8912.
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Rosa-Téllez S, Alcántara-Enguídanos A, Martínez-Seidel F, Casatejada-Anchel R, Saeheng S, Bailes CL, Erban A, Barbosa-Medeiros D, Alepúz P, Matus JT, Kopka J, Muñoz-Bertomeu J, Krueger S, Roje S, Fernie AR, Ros R. The serine-glycine-one-carbon metabolic network orchestrates changes in nitrogen and sulfur metabolism and shapes plant development. Plant Cell. 2024 Jan 30; 36(2):404-426.
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Saadalla A, Nandakumar V. Anti-phosphatidyl-serine/prothrombin (aPS/PT) antibodies are superior predictors of LAC presence and APS diagnoses: A single center study. Clin Chim Acta. 2024 Feb 01; 554:117761.
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Kyllo HM, Wang D, Lorca RA, Julian CG, Moore LG, Wilkening RB, Rozance PJ, Brown LD, Wesolowski SR. Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency. Am J Physiol Endocrinol Metab. 2023 06 01; 324(6):E556-E568.
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Lee E, Redzic JS, Saviola AJ, Li X, Ebmeier CC, Kutateladze TG, Hansen KC, Zhao R, Ahn N, Sluchanko NN, Eisenmesser E. Molecular insight into the specific interactions of the SARS-Coronavirus-2 nucleocapsid with RNA and host protein. Protein Sci. 2023 04; 32(4):e4603.
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Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. An atlas of substrate specificities for the human serine/threonine kinome. Nature. 2023 01; 613(7945):759-766.
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Xia C, Suriyanarayanan S, Gong Y, Fridman V, Selig M, Li J, Rutkove S, Hornemann T, Eichler F. Long-term effects of l-serine supplementation upon a mouse model of diabetic neuropathy. J Diabetes Complications. 2023 02; 37(2):108383.
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Halloran KM, Stenhouse C, Moses RM, Kramer AC, Sah N, Seo H, Lamarre SG, Johnson GA, Wu G, Bazer FW. The ovine conceptus utilizes extracellular serine, glucose, and fructose to generate formate via the one carbon metabolism pathway. Amino Acids. 2023 Jan; 55(1):125-137.
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Baixauli F, Piletic K, Puleston DJ, Villa M, Field CS, Flachsmann LJ, Quintana A, Rana N, Edwards-Hicks J, Matsushita M, Stanczak MA, Grzes KM, Kabat AM, Fabri M, Caputa G, Kelly B, Corrado M, Musa Y, Duda KJ, Mittler G, O'Sullivan D, Sesaki H, Jenuwein T, Buescher JM, Pearce EJ, Sanin DE, Pearce EL. An LKB1-mitochondria axis controls TH17 effector function. Nature. 2022 10; 610(7932):555-561.
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